R & D Status November 2015
 Human African Trypanosomiasis
SCYX-7158 progresses to Phase II/III trial in DRC, while the fexinidazole trial is ready for extension to Phase IIIb including new patient groups not yet included in the current trial. » |
 Leishmaniasis
VL&PKDL: Preparation of two Phase II PoC studies to assess fexinidazole/miltefosine combination and two treatments (AmBisome monotherapy and in combination with miltefosine) for PKDL.
CL: Phase II trial on Anfoleish progresses, while Phase II PoC study on new combination treatments is under preparation. » |
 Chagas disease
Preparations underway for Phase II PoC study of benznidazole monotherapy in new doses and durations and benznidazole / fosravuconazole combination regimens, in Argentina and Bolivia. » |
 Filarial diseases
A macrofilaricide drug is ready for testing in human volunteers in a Phase I study. » |
 Paediatric HIV
Large-scale implementation study on LPV/r pellets with NRTI FDC and preparation of Phase I study in human volunteers to test 4-in-1 LPV/r based FDC granules. » |
 Mycetoma
Preparation is underway for a Phase II PoC study to assess fosravuconazole in patients with eumycetoma in Sudan. » |
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