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Cardiology Evidence Update

March 2017
 

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ENDURALIFE powered CRT-D devices for treating heart failure
Medical technologies guidance [MTG33] Published date: March 2017

End of life care for adults
Quality standard [QS13] Published date: November 2011 Last updated: March 2017
 
Care of dying adults in the last days of life
Quality standard [QS144] Published date: March 2017 
Cochrane Systematic Reviews

Practice changing updates

TopicPercutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) for STEMI
Change: single-vessel PCI associated with similar risk of in-hospital mortality, but decreased risk of postprocedural complications compared to multivessel PCI in patients with hemodynamically stable STEMI (Am J Cardiol 2016 Oct 1)
 
Topic: Cardiac arrest in adults
Change: tracheal intubation during first 15 minutes of resuscitation associated with reduced survival to discharge in adults with in-hospital cardiac arrest (JAMA 2017 Feb 7)

UpToDate

These topics have been updated:

MRI in patients with pacemakers or implantable cardioverter-defibrillators (March 2017)

Switching MI patients from ticagrelor to clopidogrel (March 2017)

Other Systematic Reviews

To access full text you may have to log in to your NHS Athens account (click here to register for free). If full text is not available then please email us to request a copy.

Oral anticoagulants for primary prevention, treatment and secondary prevention of venous thromboembolic disease, and for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis and cost-effectiveness analysis. (NIHR Health Technology Assessment)

Effectiveness of expanded cardiac rehabilitation in patients diagnosed with coronary heart disease: a systematic review protocol. (Joanna Briggs Institute Systematic Review)



Accuracy and precision of non-invasive cardiac output monitoring devices in perioperative medicine: a systematic review and meta-analysis.
 
Antibiotic prophylaxis for infective endocarditis: a systematic review and meta-analysis.
 
Are cardiovascular risk factors also associated with the incidence of atrial fibrillation? A systematic review and field synopsis of 23 factors in 32 population based cohorts of 20 million participants.

Bivalirudin versus heparin in women undergoing percutaneous coronary intervention: A systematic review and meta-analysis of randomized clinical trials.

Bleeding events associated with a low dose (110 mg) versus a high dose (150 mg) of dabigatran in patients treated for atrial fibrillation: a systematic review and meta-analysis.
 
Comparison of late mortality after transcatheter aortic valve implantation versus surgical aortic valve replacement: Insights from a meta-analysis.

Cost-effectiveness of a text message programme for the prevention of recurrent cardiovascular events.

Device-associated thrombus formation after left atrial appendage occlusion: A systematic review of events reported with the Watchman, the Amplatzer Cardiac Plug and the Amulet.
 
Direct Oral Anticoagulants in Patients With Atrial Fibrillation and Valvular Heart Disease Other Than Significant Mitral Stenosis and Mechanical Valves: A Meta-Analysis.
 
Duration of dual antiplatelet therapy in acute coronary syndrome.
 
Factors related to self-care behaviours in heart failure: A systematic review of European Heart Failure Self-Care Behaviour Scale studies.

Heart Rhythm Society: expert consensus statements
Part 1Part 2.
 
Intravascular ultrasound-guided vs angiography-guided drug-eluting stent implantation in complex coronary lesions: Meta-analysis of randomized trials.
 
Meta-Analysis of Randomized Clinical Trials Comparing Biodegradable Polymer Drug-Eluting Stent to Second-Generation Durable Polymer Drug-Eluting Stents.
 
Meta-Analysis of Randomized Control Trials Comparing Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Significant Left Main Coronary Narrowing.

Natriuretic peptides in the evaluation and management of degenerative mitral regurgitation: a systematic review.
 
Outcomes in hypertrophic cardiomyopathy patients with and without atrial fibrillation: a survival meta-analysis.

Outcomes of Coronary Artery Bypass and Stents for Unprotected Left Main Coronary Stenosis.

Pacing as a Treatment for Reflex-Mediated (Vasovagal, Situational, or Carotid Sinus Hypersensitivity) Syncope: A Systematic Review for the 2017 ACC/AHA/HRS Guideline for the Evaluation and Management of Patients with Syncope: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.
 
Patient values and preferences for antithrombotic therapy in atrial fibrillation. A Narrative Systematic Review.
 
Percutaneous Ventricular Assist Devices: A Health Technology Assessment.
 
Potential Deaths Averted and Serious Adverse Events Incurred from Adoption of the SPRINT Intensive Blood Pressure Regimen in the U.S.: Projections from NHANES.
 
Pre-Implantation Balloon Aortic Valvuloplasty and Clinical Outcomes Following Transcatheter Aortic Valve Implantation: A Propensity Score Analysis of the UK Registry.
 
The prevalence of frailty in heart failure: A systematic review and meta-analysis.
 
Pulmonary Embolism and Atrial Fibrillation: Two Sides of the Same Coin? A Systematic Review.
 
Strategies to improve self-management in heart failure patients.
 
Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies.
 
Tai Chi Exercise for Patients with Chronic Heart Failure: A Meta-analysis of Randomized Controlled Trials.

Vitamin C for preventing atrial fibrillation in high risk patients: a systematic review and meta-analysis.
Leicester Publications

To access full text you may have to log in to your NHS Athens account (click here to register for free). If full text is not available then please email us to request a copy.

Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.

The CAPS Study: incidence, management and outcomes of cardiac arrest in pregnancy in the UK: a prospective, descriptive study.
 
Cardiovascular magnetic resonance evaluation of symptomatic severe aortic stenosis: association of circumferential myocardial strain and mortality.
 
Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) Study.

Development and validation of multivariable models to predict mortality and hospitalization in patients with heart failure.

Impact of failed mitral valve repair on hospital outcome of redo mitral valve procedures†.

Inadequacy of existing clinical prediction models for predicting mortality after transcatheter aortic valve implantation.

Initial Experience of a Second-Generation Self-Expanding Transcatheter Aortic Valve: The UK & Ireland Evolut R Implanters' Registry.

An interactive platform to guide catheter ablation in human persistent atrial fibrillation using dominant frequency, organization and phase mapping.

Myocardial strain and symptom severity in severe aortic stenosis: insights from cardiovascular magnetic resonance.

Native T1 mapping: inter-study, inter-observer and inter-center reproducibility in hemodialysis patients.

Post-Carotid Endarterectomy Hypertension. Part 1: Association with Pre-operative Clinical, Imaging, and Physiological Parameters.

Prognostic Role of Molecular Forms of B-Type Natriuretic Peptide in Acute Heart Failure.

A risk scoring system to predict coronary stent thrombosis.

Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.

Unwarranted Variation in the Quality of Care for Patients With Diseases of the Thoracic Aorta.
 
We would like to know...  

...if journal clubs improve patient care and decision making?   Do they help put evidence into practice?

If you attend a journal club, please fill in our 12 question survey at http://bit.ly/2j7VfHh.
NHS Behind the Headlines - media stories explained

Ibuprofen claimed to raise cardiac arrest risk by a third

Regular activity may help some people stay "fat and fit"

Early warning signs of some cases of heart attacks 'being missed'
Can you offer help with statistics?

The Library is compiling a list of people who can offer colleagues help with doing statistics.  We have already compiled some resource sheets, available from here.  Some people have access to help (for example, through a local University, from other members of the research team, or from the sponsor or organiser of the research). But some do not.  Could you help?

People in search of help would contact the Library, and the Library would forward their enquiry to people on the list.
 
To join this list, and receive requests for help, please fill in this form at
 
http://bit.ly/2jF227j  
 
You can find out a bit more about the scheme there too.
News and Reports
 
100000 Genomes Project

An NHS project, an excellent opportunity for patients with rare conditions and certain cancers, and their families, to obtain a genetic diagnosis by genomic sequencing. It aims to sequence 100,000 genomes from NHS patients by 2018. 

Overall, this project aims to improve and personalise patient treatment and care, develop a genomic medicine service for the NHS and find new scientific discoveries and medical insights.

More information here.

UHL project members have produced “Eligibility Wheels” as a simple guide to help clinicians identify potential participants to join the 100,000 Genomes Project.   The wheels bring together conditions that would be seen by a physician in a clinic setting. They can be displayed in clinical areas where most useful, such as on consultation room noticeboards or in toggled booklets.  For assistance with collating specialty specific  printouts (laminated for display or toggled) please make contact (details below).  Contact will be made with the relevant specialities soon. You can download the Eligibility Wheels from the following link: https://www.genomicseducation.hee.nhs.uk/taught-courses/eligibility-wheels-library/ .  

Please share this information with other colleagues that see patients who may be eligible to participate in this project.
 
If you have any further enquiries, please contact the Leicester recruitment team via email: genomesproject@uhl-tr.nhs.uk  or by telephone on: 0116 258 6968.  
 

The 66th Annual Scientific Session and Expo of the American College of Cardiology takes place in Washington DC from March 17th - 19th.

NHS England confirms Riociguat will be available under certain circumstances for treatment of pulmonary hypertension.

Tackling high hlood pressure through community pharmacy (Pharmacy Voice and Public Health England)

Resuscitation to recovery: A National Framework to improve care of people with out-of-hospital cardiac arrest (OHCA) in England 

Responding to domestic abuse: a resource for health professionals. (Department of Health)

Fair care for trans patients: an RCN guide for nursing and health care professionals.

Transition from Children’s to Adult Community Services Learning Resource (Queen's Nursing Institute)
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