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Cardiac Surgery Evidence Update

March 2017

End of life care for adults
Quality standard [QS13] Published date: November 2011 Last updated: March 2017

Care of dying adults in the last days of life
Quality standard [QS144] Published date: March 2017 
Leicester Publications

Common congenital cardiac disease with uncommon postoperative complication.

A Phase I study to determine the pharmacokinetic profile, safety and tolerability of sildenafil (Revatio) in cardiac surgery: the REVAKI-1 study

New topic: Percutaneous coronary intervention (PCI) procedure

Topic: Percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) for STEMI
Change: single-vessel PCI associated with similar risk of in-hospital mortality, but decreased risk of postprocedural complications compared to multivessel PCI in patients with hemodynamically stable STEMI (Am J Cardiol 2016 Oct 1)

Topic: Stenting during percutaneous coronary intervention (PCI)
Change: restenting with everolimus-eluting and zotarolimus-eluting stents associated with similar rate of major adverse cardiovascular events in adults with drug-eluting stent restenosis (Eur Heart J 2016 Dec 1)

Topic: Glycemic goals in type 1 diabetes
Change: intensive insulin therapy might decrease long-term rate of cardiovascular events in patients with type 1 diabetes (Diabetes Care 2016 May)
Cochrane Systematic Reviews
Other Systematic Reviews

To access full text you may have to log in to your NHS Athens account (click here to register for free). If full text is not available then please email us to request a copy.

Acute Normovolemic Hemodilution Reduces Allogeneic Red Blood Cell Transfusion in Cardiac Surgery: A Systematic Review and Meta-analysis of Randomized Trials.

Additional mitral valve procedure and coronary artery bypass grafting versus isolated coronary artery bypass grafting in the management of significant functional ischemic mitral regurgitation: a meta-analysis.

Administration of lidocaine to prevent cognitive deficit in patients undergoing coronary artery bypass grafting and valve plasty: a systematic review and meta-analysis.

Body Mass Index and Mortality Among Adults Undergoing Cardiac Surgery: A Nationwide Study With a Systematic Review and Meta-Analysis.

Cardiac surgery as a stressor and the response of the vulnerable older adult.

Clinical effectiveness of individual patient education in heart surgery patients: A systematic review and meta-analysis.

Clinical Outcomes of Remote Ischemic Preconditioning Prior to Cardiac Surgery: A Meta-Analysis of Randomized Controlled Trials.

Computerised insulin dosing calculators for the management of continuous insulin infusions after cardiac surgery: A systematic review and meta-analysis.

Defining the role of perioperative statin treatment in patients after cardiac surgery: A meta-analysis and systematic review of 20 randomized controlled trials.

Dexmedetomidine vs propofol sedation reduces delirium in patients after cardiac surgery: A meta-analysis with trial sequential analysis of randomized controlled trials.

Effects of early mobilisation in patients after cardiac surgery: a systematic review.

Efficacy and safety of vitamin C for atrial fibrillation after cardiac surgery: A meta-analysis with trial sequential analysis of randomized controlled trials.

Efficacy of N-Acetylcysteine in Preventing Acute Kidney Injury After Cardiac Surgery: A Meta-Analysis Study.

Goal directed fluid therapy decreases postoperative morbidity but not mortality in major non-cardiac surgery: a meta-analysis and trial sequential analysis of randomized controlled trials.

Mental Health Among Parents of Children With Critical Congenital Heart Defects: A Systematic Review.

The negative chronotropic effect during lumbar spine surgery: A systemic review and aggregation of an emerging model of spinal cardiac reflex.

"Obesity paradox" in transcatheter aortic valve implantation.

Perioperative Retinal Artery Occlusion: Risk Factors in Cardiac Surgery from the United States National Inpatient Sample 1998-2013.

Predictors of total morbidity burden on days 3, 5 and 8 after cardiac surgery.

Preoperative Antihypertensive Medication in Relation to Postoperative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Meta-Analysis.

Preoperative Statin Treatment for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery: A Meta-Analysis of Randomised Controlled Trials.

Risk prediction models for delirium in the intensive care unit after cardiac surgery: a systematic review and independent external validation.

Role of statins in delirium prevention in critical ill and cardiac surgery patients: A systematic review and meta-analysis.

Seizures associated with tranexamic acid for cardiac surgery: a meta-analysis of randomized and non-randomized studies.

The Society of Thoracic Surgeons Expert Consensus for the Resuscitation of Patients Who Arrest After Cardiac Surgery.

Systematic review of a patient care bundle in reducing staphylococcal infections in cardiac and orthopaedic surgery.

A systematic review of postoperative cognitive decline following open and endovascular aortic aneurysm surgery.

Systematic review on the predictive ability of frailty assessment measures in cardiac surgery.

The use of therapeutic magnesium for neuroprotection during global cerebral ischemia associated with cardiac arrest and cardiac surgery in adults: a systematic review.  (Joanna Briggs Institute)
We would like to know...  

...if journal clubs improve patient care and decision making?   Do they help put evidence into practice?

If you attend a journal club, please fill in our 12 question survey at http://bit.ly/2j7VfHh.
News and reports

100000 Genomes Project

An NHS project, an excellent opportunity for patients with rare conditions (including some congenital heart conditions), and certain cancers, and their families, to obtain a genetic diagnosis by genomic sequencing. It aims to sequence 100,000 genomes from NHS patients by 2018. 

Overall, this project aims to improve and personalise patient treatment and care, develop a genomic medicine service for the NHS and find new scientific discoveries and medical insights.

More information here.  

UHL project members have produced “Eligibility Wheels” as a simple guide to help clinicians identify potential participants to join the 100,000 Genomes Project.   The wheels bring together conditions that would be seen by a physician in a clinic setting. They can be displayed in clinical areas where most useful, such as on consultation room noticeboards or in toggled booklets.  For assistance with collating specialty specific  printouts (laminated for display or toggled) please make contact (details below).  Contact will be made with the relevant specialities soon. You can download the Eligibility Wheels from the following link: https://www.genomicseducation.hee.nhs.uk/taught-courses/eligibility-wheels-library/ .  

Please share this information with other colleagues that see patients who may be eligible to participate in this project.
 
If you have any further enquiries, please contact the Leicester recruitment team via email: genomesproject@uhl-tr.nhs.uk  or by telephone on: 0116 258 6968.  
 

Mycobacterium chimaera Spread from Heating and Cooling Units in Heart Surgery  (a letter to the NEJM)

Responding to domestic abuse: a resource for health professionals. (Department of Health)

Fair care for trans patients: an RCN guide for nursing and health care professionals.

Transition from Children’s to Adult Community Services Learning Resource (Queen's Nursing Institute)
Can you offer help with statistics?

The Library is compiling a list of people who can offer colleagues help with doing statistics.  We have already compiled some resource sheets, available from here.  Some people have access to help (for example, through a local University, from other members of the research team, or from the sponsor or organiser of the research). But some do not.  Could you help?

People in search of help would contact the Library, and the Library would forward their enquiry to people on the list.
 
To join this list, and receive requests for help, please fill in this form at
 
http://bit.ly/2jF227j  
 
You can find out a bit more about the scheme there too.
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UHL Clinical Librarian Service · Education Centre · Glenfield Hospital · Leicester, LE3 9QP · United Kingdom

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