Removing Senescent Cells To Treat Osteoarthritis: More evidence for the benefits of senescent cell removal emerges, as research suggests targeted clearance can alleviate osteoarthritis in mice. Source
Sirtuin 6 Improves Healthspan In Mice: Introducing extra copies of SIRT6 improves mice healthspan, while reduced levels are correlated with neurodegeneration. Source
Why Do Our Cells Contain So Much ATP?: Our cells contain a surprisingly high amount of ATP. A new paper published in Science suggests one reason is that high levels of ATP help to keep the proteins in our cell soluble. The age-related decrease in ATP may therefore contribute to protein aggregation. Source
A Worm Autopsy: What Actually Kills Worms?: C. elegans appear to die primarily as a result of bacterial invasion. Source
Scientists reverse mechanism of fatty liver disease: A group of international researchers publishing today in the journal Nature Communications, report that senescent or old cells in the liver store excessive fat because mitochondria, the batteries of the cells, become damaged and cannot effectively use the fat as a source of fuel, resulting in its storage. Source
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