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Issue 06  16 December 2016
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Report from International Science Advisory Group meeting, 6 December

Andrew, Vicky and staff were very pleased to welcome colleagues from across three continents to the first face-to- face ISAG meeting, held at the EMBL-ABR Hub in Melbourne. Throughout the day the Group heard about the exciting developments in major Australian life science projects and of efforts being made by EMBL-ABR and other groups such as ABACBS to build support for bioinformatics here.

Chair, ISAG, Jason Williams stayed on to work and teach with us at the EMBL-ABR Hub and offered his reflection on the ISAG meeting:
I think the ISAG was very impressed with the progress of EMBL-ABR. One of the reasons for having such a group is to ensure that the quality of the science EMBL-ABR will enable is world-class. We certainly saw this standard in the calibre of the science being presented, the professional organisation of the meetings, and the timely workshop topics. Australia’s unique datasets and research infrastructure are of tremendous value, and we look forward to the positive impact EMBL-ABR will have in realising greater opportunities for discovery. 

A full report from the ISAG to the EMBL-ABR Executive is expected early in the new year.



ISAG members, L-R: Tony Papenfuss, Rebecca Johnson, Vivien Bonazzi, Jason Williams, Paul Flicek, Sean Grimmond, Jaap Heringa, Delphine Fleury, Mark Walker, (absent, Jenny Martin).

Andrew Lonie was extremely grateful for the Group's time and efforts: Their high calibre and expertise reflects the increasing transformation of biology into a rich data science impacting health, society and industry. We welcome their insights and advice as we work out the best way to develop this crucial network.


Andrew and Vicky also thanked key presenters on the day including Sonika Tyagi (AGRF Node), Steve Androulakis (Monash University Node), Saravanan Dayalan (Metabolomics Australia Node), Philippa Griffin (Open Data Coordinator), Torsten Seemann (Antibiotic Resistant Pathogens Project), Andrew Pask (Wallabase), Rebecca Johnson (OzMammals) and Helen Gardiner (Communications).
December workshops - presentations now available

Rafael Jimenez (Chief Technical Officer, ELIXIR Hub, UK) and Vicky Schneider (EMBL-ABR Deputy Director) were joined by Jason Williams (CyVerse) in delivering the following best practice in bioinformatics workshops in Melbourne this month. Link on each one to access full presentations and documentation:

Open Source and Software Development Best Practice

This workshop looked at CyVerse and ELIXIR Software Development Best Practices to explore how we might harmonise our efforts in this area in Australia. 


Registries in Bioinformatics: tools, datasets, standards, events & training

An introduction to existing solutions and methods for selecting and accessing these registries.

Open & Scalable Training

This session considered the demands in Australia for bioinformatics training: are they being met, how do we compare with the rest of the world, and could we scale up and share training expertise, employing the principles of open software and open data as applied to training?

 

Another very successful BioInfoSummer
28 Nov - 2 Dec

Each year Bioinfosummer, organised by the Australian Mathematical Sciences Institute (AMSI), attracts over 200 Australian students and researchers to a week-long symposium on the world of bioinformatics.

This year it was held in Adelaide, South Australia. Open Data Coordinator, Philippa Griffin, represented EMBL-ABR, delivering a comprehensive overview of the national and international research infrastructure for the life sciences and showing EMBL-ABR's activity across this landscape. She welcomed lots of 
insightful questions and comments.

Highlights of the program for Pip were Katherine Pillman's talk on differential splicing quantification in RNA-seq, Denis O'Meally's talk on the koala genome project, and Terry Speed's talk on the history of theoretical attempts to crack the genetic code. This story reminded us that even the most elegant mathematical theories about biology often don't survive encounters with biological data, said Pip.
Overall, it
was great to talk to enthusiastic students, ECRs and other speakers throughout an action-packed week, Pip said.

Our thanks to AMSI organisers for this opportunity to engage with this important life science community.

 
Link to Pip's Bioinfosummer presentation
Paul Flicek presenting on current EBI activities to the All-Hands meeting.

Report from All-Hands meeting 

7 December

This inaugural meeting, held in Melbourne at the EMBL-ABR Hub, attracted 62 participants from the bioinformatics communities across New South Wales, Queensland, Victoria, South Australia, Western Australia and Tasmania. They were joined by ISAG members who contributed to discussions about how this community might direct future bioinformatics network building activities in Australia.

Afterwards Vicky commented: It was great to see nine of the ten nodes represented and so many key experts from both dry and wet sciences present. Both Vivien's and Paul's talks highlighted several efforts taking place globally that are relevant to the EMBL-ABR community and I'm particularly looking forward to seeing how we can best access these to help expand our community, resources and activities through 2017.

Presentations from All-Hands
In Melbourne 
3-9 February 2017

Follow
@GalaxyAustralia
#GAMe_2017


Keynote speakers are now confirmed:

Dr James Taylor is the Ralph S. O’Connor Assoc Prof of Biology and Computer Science at Johns Hopkins University. He is one of the original developers of the Galaxy platform for data analysis, and his group works on extending the Galaxy platform, and understanding genomic and epigenomic regulation of gene transcription through integrated analysis of functional genomic data. James received a PhD in computer science from Penn State University, where he was involved in several vertebrate genome projects and the ENCODE project. 


Dr Björn Grüning is with the Bioinformatics Group at Albert-Ludwigs-Universität Freiburg, Germany, where he heads the Freiburg Galaxy Project. He is a prominent contributor to, and is a driving force in, the Galaxy community. In the past year alone, he helped organise the Bioconda Contribution Fest, Swiss-German Galaxy Days, the Galaxy Training Materials Contribution Fest, the Galaxy DevOps Workshop, and the Conda Dependencies Codefest, and presented and taught at GCC2016.  His research interests include data visualisation, computational chemistry, and drug discovery.

Current sponsors include AGRF, Cray, EMBL-ABR, Galaxy, University of Melbourne, VLSCI 

Register here
Thank you to all the Heads of Nodes for working with us on some tight timelines to have the Node flyers ready in time for the ISAG and All Hands meetings. To order printed copies, contact Christina Hall. All pdfs are now online and available for download.
Download Node flyers

ABACBS
The Australian Bioinformatics and Computational Biology Society (ABACBS) meeting ran in conjunction with the B3 symposium, the COMBINE symposium, and the GOBLET meeting, forming a 'Festival of Bioinformatics' in Brisbane in November. Pip Griffin, Open Data Coordinator and Sonika Tyagi, Training Coordinator both represented EMBL-ABR.

Pip reported that she very much enjoyed the opportunity to meet so many bioinformaticians from around Australia and to hear about their diverse research activities. She particularly enjoyed Nouri Ben Zakour's talk on tracking evolution of microbial pathogens, Jimmy Breen's talk on multi-omic analysis of old and young grapevine clones, and Terri Attwood's closing talk on biological data curation and linking the underlying research data in the scientific literature - (Terri was featured in an EMBL-ABR interview earlier this year).

Pip and Sonika also attended the GOBLET Best Practices in Bioinformatics Training meeting and commented on the excellent workshop on the mixOmics package for multi-omic data analysis. 

Global mapping of bioinformatics training in Australia

Combined surveys conducted by EMBL-ABR over 2016 have identified, among other things, specific demand for more training in data management and statistics. These results were presented at ABACBS.

ABACBS f1000 channel for all posters and presentations

Interview series: 

Jyoti Khadake was in Melbourne recently forming part of the International Faculty on the Data Life Cycle workshop series, as our expert on microbial genomic data and data accessibility and challenges. As someone who works in biomedical research, she sees the social and ethical considerations vary greatly amongst bioinformaticians, depending on their area of study, but that they all need to adopt the agreed standards for data curation and management which are being implemented across this discipline.



       
Link to this and all interviews in the series
PROFILE SERIES> 
EMBL-ABR: QCIF Node
         

QCIF is a consortium of seven leading Queensland universities and includes QFAB, the Queensland Facility for Advanced Bioinformatics. QCIF operates significant HPC, cloud computing and data storage resources, is part of the national eResearch infrastructure, offers a wide range of services across a broad spectrum of research domains and undertakes projects of local and national significance.
 
QFAB is an established and mature centre for computational life sciences expertise, providing expert consulting and services in bioinformatics to life sciences and health researchers throughout Queensland and beyond. The QCIF Node will collaborate nationally through its EMBL-ABR data chaperoning services and continued partnering in the development and operation of the Genomics Virtual Lab.
 
COMPUTE
The QCIF Node provides extensive computational facilities using high performance clusters, large memory nodes and Cloud resources to support bioinformatics data, tools and platforms. All researchers across Australia can access resources via QRIScompute. QRIScompute facilitates access to Nectar Cloud compute infrastructure including Euramoo - a cloud-based computer cluster built on the Nectar Cloud. FlashLite is a research computer that has been designed and optimised for data intensive computing, in particular for life science computing.
 
DATA
The QCIF Node facilitates a range of services including tailored data chaperoning and solutions for processing, managing, sharing and archiving high value data. Hosting and mirroring of national and international reference data collections such as the 1000 Genomes and the Bioplatforms Australia collections is provided.
 
PLATFORMS
The QCIF Node is part of a national collaborative effort to develop a platform for multi-omics analysis and interpretation that will initially support Bioplatforms Australia’s Antibiotic Resistance Pathogens Project. The QCIF Node is involved in the nationally funded eResearch infrastructure, med.data, which facilitates the discovery, storage and sharing of health datasets. The QCIF Node partners in the development of the Genomics Virtual Laboratory and provides user access and support throughout Queensland.
 
TRAINING
Empowering life science and health researchers to get the most out of their research data, the QCIF Node provides a wide range of training options to up-skill students and researchers in digital infrastructure usage, and in best practice data analysis in bioinformatics, biostatistics and health informatics.

FEBRUARY PROFILE > MONASH NODE, CLAYTON, VICTORIA

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