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The latest news, publications and events from Canadian Blood Services’ Medical Affairs and Innovation research and education network.
Collected from September 2018      
 

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Thank you for subscribing to Canadian Blood Services' monthly Research and Education Round Up newsletter. We welcome your feedback. Please share your comments and questions with us at centreforinnovation@blood.ca 
 

Our story is changing

Join us in making the connection between the sincere generosity of donors and the heartfelt appreciation of recipients, between the profound discoveries of science and the joyful restoration of health.

Find out more about how our story is changing on blood.ca

 

A new symbol for Canada's lifeline

Based on the universal shape for infinity, the design of our new logo represents the infinite lengths to which we must always go to save lives. All the while, we must recognize the connections that link us together – from donors to recipients, from transfusion to transplantation, from hearts to minds, from one to another. A vital connection between donors and recipients right across the country.

Funding competitions now open!


BloodTechNet Award Program 

Supporting the development of innovative educational projects that network the transfusion, cellular therapy and transplantation communities in Canada.  Current competition application deadline: November 30, 2018 

James Kreppner Award 

Supporting research into the legal and regulatory aspects of (a) donation, collection, storage, and use of blood, blood products, and hematopoietic stem cells; and (b) organ and tissue donation and transplantation.
Current competition application deadline: November 30, 2018 

Kenneth J. Fyke Award 

Supporting health services and policy research in order to promote the development of evidence-based Canadian practices and policies in blood transfusion, blood stem cell transplantation, and organ and tissue transplantation for the benefit of Canadian patients. 
Current competition application deadline: November 30, 2018 

Canadian Blood Services' Graduate Fellowship Program 

Providing stipend support for young investigators who want to initiate or continue training in the field of transfusion science. Graduate students undertaking full-time research training in a Canadian institution are invited to apply. Current competition application deadline: November 30, 2018

From our Research. Education. Discovery blog 

A mission to Mars caps off summer at the Centre for Blood Research

Meet the Researcher: Dr. Jelena Holovati

 

Visit blog

New publications

 

Designing the blood supply chain: how much, how and where? Osorio AF, Brailsford SC, Smith HK, Blake J. Vox Sanguinis [Epub ahead of print] doi: 10.1111/vox.12706. 

Systematic review of rituximab for autoimmune diseases: a potential alternative to intravenous immune globulin. MacIsaac J, Siddiqi R, Jamula E, Li N, Baker S, Webert KE, Evanovitch D, Heddle NM, Arnold DM. Transfusion. 2018 Sep 23. doi: 10.1111/trf.14841. [Epub ahead of print] Review. PMID: 30244480 

Genetic deficiency of the tumor suppressor protein p53 influences erythrocyte survival. Bissinger R, Lang E, Gonzalez-Menendez I, Quintanilla-Martinez L, Ghashghaeinia M, Pelzl L, Sukkar B, Bhuyan AAM, Salker MS, Singh Y, Fehrenbacher B, Fakhri H, Umbach AT, Schaller M, Qadri SM, Lang F. Apoptosis. 2018 Sep 20. doi: 10.1007/s10495-018-1481-8. [Epub ahead of print] PMID: 30238335 

Risk-based decision making in transfusion medicine. Leach Bennett J, Devine DV. Vox Sang. 2018 Sep 19. doi: 10.1111/vox.12708. [Epub ahead of print] Review. PMID: 30232803 

Severe hemolytic disease of the fetus and newborn due to allo-anti-D in a patient with a partial DEL phenotype arising from the variant allele described as RHD*148+1T (RHD*01EL.31). Turley E, McGowan EC, Hyland CA, Schoeman EM, Flower RL, Skoll A, Delisle MF, Nelson T, Clarke G, Au N. Transfusion. 2018 Sep 17. doi: 10.1111/trf.14944. [Epub ahead of print] PMID: 30222865 

Blood manufacturing methods affect red blood cell product characteristics and immunomodulatory activity. Almizraq RJ, Norris PJ, Inglis H, Menocha S, Wirtz MR, Juffermans N, Pandey S, Spinella PC, Acker JP, Muszynski JA. Blood Adv. 2018 Sep 25;2(18):2296-2306. doi: 10.1182/bloodadvances.2018021931. PMID: 30217795 

Cardiac stress biomarkers after red blood cell transfusion in patients at risk for transfusion-associated circulatory overload: a prospective observational study. Callum JL, Cohen R, Cressman AM, Strauss R, Armali C, Lin Y, Pendergrast J, Lieberman L, Scales DC, Skeate R, Ross H, Cserti-Gazdewich C. Transfusion. 2018 Sep;58(9):2139-2148. doi: 10.1111/trf.14820. PMID: 30204946 

Extending the pre-processing holding time of whole blood beyond 48 h reduces coagulation FVIII activity and immunoglobulin G content of recovered plasmaSheffield WP, Bhakta V, Jenkins C. Transfusion and Apheresis Science, In press. doi: 10.1016/j.transci.2018.09.016 

Serpin Phage Display: The Use of a T7 System to Probe Reactive Center Loop Libraries with Different Serine Proteinases. de Souza LR, Scott BM, Bhakta V, Donkor DA, Perruzza DL, Sheffield WP. Methods Mol Biol. 2018;1826:41-64. doi: 10.1007/978-1-4939-8645-3_3. PMID: 30194592 

Apolipoprotein A-IV binds αIIbβ3 integrin and inhibits thrombosis. Xu XR, Wang Y, Adili R, Ju L, Spring CM, Jin JW, Yang H, Neves MAD, Chen P, Yang Y, Lei X, Chen Y, Gallant RC, Xu M, Zhang H, Song J, Ke P, Zhang D, Carrim N, Yu SY, Zhu G, She YM, Cyr T, Fu W, Liu G, Connelly PW, Rand ML, Adeli K, Freedman J, Lee JE, Tso P, Marchese P, Davidson WS, Jackson SP, Zhu C, Ruggeri ZM, Ni H. Nat Commun. 2018 Sep 6;9(1):3608. doi: 10.1038/s41467-018-05806-0. PMID: 30190457 

Heterotrimeric G-protein subunit Gαi2 contributes to agonist-sensitive apoptosis and degranulation in murine platelets. Cao H, Qadri SM, Lang E, Pelzl L, Umbach AT, Leiss, Birnbaumer L, Nürnberg B, Pieske B, Voelkl J, Gawaz M, Bissinger R, Lang F. Physiol Rep. 2018 Sep;6(17):e13841. doi: 10.14814/phy2.13841. PMID: 30187671 

 Assessing the risk of Babesia to the United States blood supply using a risk-based decision-making approach: Report of AABB's Ad Hoc Babesia Policy Working Group (original report). Ward SJ, Stramer SL, Szczepiorkowski ZM. Transfusion. 2018 Aug;58(8):1916-1923. doi: 10.1111/trf.14912. Epub 2018 Sep 4. PMID: 30180272 

Rivaroxaban and Apixaban Induce Clotting Factor Xa Fibrinolytic Activity. Carter RLR, Talbot K, Hur WS, Meixner SC, Van Der Gugten JG, Holmes DT, Côté HCF, Kastrup CJ, Smith TW, Lee AYY, Pryzdial ELG. J Thromb Haemost. 2018 Sep 3. doi: 10.1111/jth.14281. [Epub ahead of print] PMID: 30176116 

Screening of red blood cells for extracellular vesicle content as a product quality indicator. Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E. Transfusion. 2018 Sep;58(9):2217-2226. doi: 10.1111/trf.14782. Epub 2018 Aug 31. PMID: 30168148 

Search our publications database on blood.ca 

Upcoming events

American Society of Histocompatibility & Immunogenetics Annual Meeting
When: October 1 – 5, 2018
Where: Baltimore, MD. 

AABB 2018 Meeting
When: October 12-16, 2018
Where: Boston 
Going to AABB? Canadian Blood Services' Centre for Innovation team members will be there too! 

Canadian Transplant Summit
When: October 16-20, 2018 
Where: Ottawa 

Canadian Cardiovascular Congress 2018,
When: October 20 – 23, 2018
Where: Toronto, ON. 

2018 BC PBCO Education Session 
When: October 25, 2018,
Where: Sidney, BC | This session will also be broadcast via webinar. 

2018 Saskatchewan Transfusion Medicine Symposium
When: October 26, 2018
Where:  Regina, SK.| This symposium will also be webcast. 

Critical Care Canada Forum 2018
When: November 6-9, 2018
Where: Toronto

Earl W. Davie Symposium
When: November 15, 2018 
Where: Centre for Blood Research, Vancouver

60th American Society of Hematology (ASH) Annual Meeting and Exposition
When: December 1-4, 2018
Where: San Diego
 
View all events



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Developed in collaboration with the Canadian Blood Services Centre for Innovation. Please provide feedback on this update to Communications via Jenny Ryan jenny.ryan@blood.ca

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