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Newsletter #118
November 23th, 2017
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Editorial

Dear friends,

In this newsletter, we highlight a new idea in the literature about dysbiosis, which takes inspiration from Tolstoy's Anna Karenina -- that healthy microbiomes might be similar, but that each dysbiotic microbiome might be dysbiotic in its own way.

Descriptions of three recent human studies follow: (1) a study on how supplementation with Bifidobacterium strains may modulate the faecal microbiota in healthy infants during the first year of life; (2) a publication showing that gut microbiota composition is associated with simultaneous use of multiple drugs in hospitalized older adults; and (3) an observational study showing how omega-3 fatty acids correlate with gut microbiota composition in middle-aged and elderly women.

The GMFH publishing team

New hypothesis: ‘All healthy microbiomes are similar; each dysbiotic microbiome is dysbiotic in its own way’
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Supplementation with Bifidobacterium strains may modulate the faecal microbiota and metabolites of healthy infants during the first year of life


It is suspected that early-life gut microbiota colonization can result in long-lasting consequences that may increase the risk of chronic diseases in adulthood. The first 3 years of life appear to represent the most critical...


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Gut microbiota composition is associated with the simultaneous use of multiple drugs in hospitalized older adults


Previous studies have found that ageing is related to decreased gut microbiota diversity and increased opportunistic pathogens together with a low-grade inflammatory state, which may lead to an increased morbidity and frailty. By contrast, long-lived...


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Observational study shows omega-3 fatty acids correlate with gut microbiota composition in women


Dietary components’ effects on host health are thought to be mediated in part by their specific effects on the gut microbiome. Probiotics and prebiotics are the most studied substrates, whereas little is known about the...


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