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Canadian Glycomics Network
May 2018
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May 2018
 
In this Issue: 

Made to measure sugar-like molecule could improve cancer-fighting antibodies


GlycoNet funds project to produce fucosylation inhibitor for cancer therapies     


by Bernie Poitras 

Dr. Robert Britton firmly believes every molecule is important. This chemist doesn’t want any molecule sitting unused on a laboratory shelf or in a fridge.

“I want every molecule to have a purpose – that’s my ethos for our lab,” says Britton, a GlycoNet Network Investigator and professor at Simon Fraser University.

With that spirit in mind, Britton has embarked on an ambitious project to develop carbohydrate mimics to assist cancer therapies by making them more selective in how they target and kill cancer cells.

Read more...

Science, scenery, socks and social networking


Third Annual Canadian Glycomics Symposium & AGM wraps up
in majestic Canadian Rockies


by Bernie Poitras 

More than 225 participants took in the 2018 Canadian Glycomics Symposium and Annual General Meeting (AGM) May 7-11 in scenic Banff.

“This is an important event for the Canadian glycomics community because it’s the only national event where we can network, review projects and collaborate face to face about our ongoing projects, and also hear about cutting-edge science from outside of Canada,” says Todd Lowary, Scientific Director, GlycoNet. “This whole week really underscores the value we place on collaboration and sharing information to achieve scientific breakthroughs. We get work done, but we also have some fun too.”

The week began with the AGM on May 7 and 8 with project presentations from Network Investigators and skills development workshops for HQP trainees.

Read more...

48Hour Discovery sign license agreement with TumorGenesis Inc. 


Precision Therapeutics Inc. (NASDAQ:AIPT) (“Precision” or “the Company”), formerly Skyline Medical, announced today that its wholly owned subsidiary, TumorGenesis Inc., has secured a license agreement with 48Hour Discovery (“48HD”) which grants it access to 48HD’s ligand discovery technology.

This follows a license agreement with SyntArray, LLC, announced on March 13th, and is the latest milestone in the Company’s strategy to bring together ground-breaking technologies to develop the next generation of patient derived (“PDx”) tumor models for precision cancer therapy and drug development.

Read full news release...

GlycoNet Board Chair launches new biotech company in Canada 


We are delighted to congratulate our Chair, Frank Gleeson on the founding and launch of a new entrant on Canada’s biotechnology scene – Satellos Bioscience Inc.

Frank has teamed up with his long-time colleague Dr. Michael Rudnicki — the Scientific Director of a fellow NCE, the Stemcell Network of Canada — and Canada’s premier healthcare investment bank Bloom Burton as co-founders of the company.

Based on a series of landmark discoveries in Dr. Rudnicki’s lab elucidating mechanisms which regulate muscle stem cell division and differentiation, Satellos aims to harness these intrinsic mechanisms using small molecules to create a new therapeutic paradigm.

More specifically, Satellos has discovered a novel target which modulates the orientation by which stem cells divide and replenish (called polarity) and shown its potential relevance to the treatment of Duchenne Muscular Dystrophy (DMD), a severe genetic disease of children that currently leads to death in early adulthood. Satellos has completed a seed round of funding to advance its drug discovery and development activities in DMD and other musculoskeletal diseases, and to expand its polarity regulating platform into neuronal cell regeneration.

The company closed a seed round of financing at the beginning of May.


We want your opinion!
Fill out the 2018 Canadian Glycomics Symposium Survey

 

SMRTS Webinar: Write the Right Grant - June 11


Hosted by the McMaster Institute for Research on Aging
Speaker: Dr. Parminder Raina, McMaster University
11 a.m. - 12 p.m. MDT

Writing successful grants is part science and part art form. What are the metrics for success? What’s the best way to incorporate your research plan and team members? How can you convincingly “sell” the funder?

This webinar will share approaches to articulating the vision and impact of your research to the review committee, and will include examples of successful proposals as well as submissions that were not funded. Learn best practices and strategies to optimize your chances for success.

Registration link: http://bit.ly/writetherightgrant
Session number: 665 349 304
Session password: mira

Congrats to the Twitter photo contest winners!
Dr. Warren Wakarchuk (@wakarchuk) & Alysha Burnett (@lyshburnett)
 
Apply to serve on the 2018-2019 GTA-EC
Click here
Applications will be accepted until June 8th at 4:00 pm MST
For more information please contact Ryan Snitynsky
 
Trainees at 2018 AGM and Symposium
HQP Training Awards: Application Deadlines

A friendly reminder to HQP to submit their applications for training awards. These are a great opportunity to broaden your training experiences and extend your network.

GlycoNet Supported Awards
Research Exchange Program



Advanced Training Opportunity Program (ATOP) Award
Summer Awards for Undergraduate Students

Mitacs Supported Industrial Internships
       September 15, 2018
       January 15, 2019
       May 15, 2019

       January 15, 2019
       February 1, 2019
Mitacs Industrial Internships – National        Ongoing basis
Mitacs Globalink Partnership Award – International        Ongoing basis
 
For detailed information about each award and access to application forms, please follow the link provided below:  
Are you interested in writing blogs on professional development?
  Feel free to contact us for details on how to get started!
Email Ali or Hanna
Akay Akohwarien, University of Saskatchewan
 
Where do you work, what is your position and who is your supervisor?
"I am a master's student in chemistry at the University of Saskatchewan with Dr. David Palmer as my supervisor."

Which project do you work on?
"My project involves the synthesis of novel candidates and PET precursor molecules for studying Glucocerebrosidase (an enzyme that is associated with Gaucher’s and Parkinson’s disease)."

If you have previously attended the AGM/Symposium, what was your experience?
"The AGM/Symposium of 2018 is my first experience at a GlycoNet hosted conference."

Where do you see yourself in the future?
"Some of the most enjoyable aspects of my work are teaching chemistry labs and attending conferences where I present my research. Both of these have provided an opportunity for science communication. In the future, I see myself teaching in some form. I would like to do a PhD in pharmaceutical chemistry and lecture at the university level, be it in Canada or Nigeria (my home country)."
 
What does glycomics mean to you?
"When I think about macromolecules, particularly enzymes, I am so fascinated by their complexities. Enzymes have evolved to have different domains, catalytic efficiency, substrate selectivities, etc. Since the learning is endless, there's always something new to discover in both research and other aspects of life. What this says to me, is to live a life driven by curiosity."

What is your favourite quote?
"Be the change you wish to see in the world” – Gandhi. I particularly like this quote because it emphasizes giving back to one's community and the need to engage with things in our world. I have been fortunate to be part of social justice work outside of campus here in Saskatoon. My work on/off campus makes my life fulfilling."
 
Based on your experience what advice would you give to junior trainees?
"Research and graduate school are steep learning experiences, particularly if you are "fresh" from undergraduate. But, that's ok. Prioritizing self-motivation, time management, self-care is crucial for staying and doing well in the graduate program. Also, do no linger too much on failures, learn from it and move on! There are things that would have been helpful to know when I started."
 
GlycoNet members in the news

Congratulations to all those recently published!

                                                                                                                                             
Selected publications:

Remember to cite the GlycoNet doi: 10.13039/501100009056 

We want to hear from you! 
Communicating your research findings is an important responsibility as a scientist. GlycoNet is here to support and promote communication of your research, but we need your help. Send photos, successes, milestones and information about awards and press coverage that you've received to glyconet@ualberta.ca.
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