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I hope this Future of Health and Medicine update finds you well. The pace of change in healthcare has been dramatically catalyzed by COVID-19; for a greater awareness of 'how' see the recent news and publications I've curated below. Chronic diseases are however still with us, and our featured xMed talk explores new approaches to stopping neurodegenerative disease.
Preventing Alzheimer's: Our lifespan has outpaced our brain's healthspan. Harvard professor of neurology Rudolph Tanzi has been at the leading edge of neuroscience as co-director of the Center for Brain Health at Mass General Hospital. His work illuminates the key role of neuroinflammation in Alzheimer's disease and the potential to stop it before symptoms emerge. Like cholesterol and heart disease, waiting for late-stage disease to initiate statin therapy is too late. Leveraging primary prevention and early detection modalities (i.e. imaging, polygenenic risk scores, to blood tests & eye-tracking modalities) and an early response will be key. In Dr. Tanzi's terrific talk at Exponential Medicine 2019, he explores the biology, new therapy approaches, including leveraging 3D brain organoid dish models, to developing an understanding and bring a future with personalized treatment, targeting the right pathology, with the right interventions at the right time. Dr. Tanzi closes with lessons on how to protect your brain, summarized by SHIELD (Sleep, Handling stress, Interaction with others, Exercise, Learning new things, and Diet).
TOP NEWS, INITIATIVES & RESOURCES
Initiatives & News From Exponential Medicine Faculty
What Do Your Genetics Have to Do With Your Chances of Dying From Coronavirus? (David Ewing Dunan, Vanity Fair)
OneSharedWorld - Declaration of Interdependence (Jamie Metzl)
Dispatch #8 | The Great Pause (Jordan Shlain)
End Well Innovation Virtual Pitch Competition (Shoshana Ungerleider, EndWell Project)
COVID-19 The Nurse Response: On Life Support - See You Now Podcast (Shawna Butler)
The Big Picture
Three potential futures for Covid-19: recurring small outbreaks, a monster wave, or a persistent crisis (STAT)
COVID-19 Simulator- An interactive tool to inform COVID-19 intervention policy decisions
What the Coronavirus Models Can’t See (NYMag)
Coronavirus: Prevent Seeding and Spreading (Tomas Pueyo)
For refugees, a plea: You can’t beat a pandemic by leaving people out (CS Monitor)
9 ways Covid-19 may forever upend the U.S. health care industry (STAT)
Triage & Diagnostics
CRISPR–Cas12-based detection of SARS-CoV-2 (Nature)
Rising to the COVID-19 Challenge: Rapid Acceleration of Diagnostics (NIH)
How What You Flush Is Helping Track The Coronavirus (NPR)
What Do Your Genetics Have to Do With Your Chances of Dying From Coronavirus? (Vanity Fair)
Doctors are using AI to triage covid-19 patients. The tools may be here to stay (MIT)
Spot the Coronavirus Doctor Robot Dog Will See You Now (WIRED)
Drugs & Vaccines
The Coronavirus Vaccine Is on Track to Be the Fastest Ever Developed (New Yorker)
China's COVID-19 vaccine trial shows promising results (Lancet)
Coronavirus Vaccine Infographic (Nature)
T cells found in COVID-19 patients ‘bode well’ for long-term immunity (Science)
The best treatment for COVID-19 may be a cocktail of medicines (Boston Globe)
To counter the pandemic, clinicians bank on repurposed drugs (PNAS)
UCSF team has discovered drugs that block coronavirus, paving way for 'a better drug sooner' (SF Chronicle)
A real-time dashboard of clinical trials for COVID-19 (Lancet)
In Race for a Coronavirus Vaccine, an Oxford Group Leaps Ahead (NYTimes)
Hospitals and Healthcare Delivery
What the Coronavirus Crisis Reveals About American Medicine (New Yorker)
Hospitals Knew How to Make Money. Then Coronavirus Happened. (NYTimes)
CVS and UPS to Use Drones to Deliver Prescriptions in a Retirement Community (NBC)
NVIDIA’s chief scientist developed a low-cost, open-source ventilator (Engadget)
Telehealth’s future is bright. Here’s what it’ll look like in 2025 (Fast Company)
Digital Health
Covid-19 pandemic accelerates digital health reforms (FT)
A Pandemic Benefit: The Expansion of Telemedicine (NYTimes)
App Shows Promise in Tracking New Coronavirus Cases, Study Finds (NYTimes)
Electric Stimulation Gives Robot-Assistive Surgery a Sense of Touch (MedGadget)
Akili's digital therapeutic launches early for housebound children with ADHD (MobiHealth)
SafeDistance Device to Help Return to Normal (MedGadget)
Apple, Google's contact tracing API goes live (MobiHealth)
Neuroscience + Mental Health
Preventing a Parallel Pandemic — A National Strategy to Protect Clinicians’ Well-Being (NEJM)
A Neuroscience Startup Uses Helmets to Measure Brain Activity (Bloomberg)
Psychedelic Pioneer Rick Doblin On FDA Trials Of MDMA: Most Important Reality Check Of MAPS’ 34-Year History (Forbes)
A secret experiment revealed: In a medical first, doctors treat Parkinson’s with a novel brain cell transplant (STAT)
When Algorithms Are Running the Asylum (Neo.Life)
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