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Co-founded by GlycoNet Investigator, the biopharma company is developing a semi-synthetic vaccine in the preclinical phase.
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48Hour Discovery aims to develop clinically useful compounds by December 2020.
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Network Investigator teams up with researchers to look for action against deadly human virus.
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GlycoNet Investigators are looking for lead antiviral compounds for more effective COVID-19 treatments.
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Dr. Dawn Bowdish, Network Investigator, was interviewed in the latest Scientific American.
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Network Investigator Dr. Burrows gives a commentary on Global News.
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We have worked to transition the in-person poster session from the now-canceled Symposium to a virtual event where researchers can interact and network through live presentations. Learn more >>
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GlycoNet is providing support for collaborations between academic researchers, public and not-for-profit sectors, and industry to address unmet healthcare needs. We encourage researchers who have innovative glycomics solutions for COVID-19 to apply ASAP. Next application deadline is June 15, 2020. Learn more >>
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What's good about pursuing a post-doc and what are some cautionary tales?
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Dr. Rahfeld has a passion for CAZymes. Find out why.
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Selected publications:
Remember to cite the GlycoNet doi: 10.13039/501100009056
- Nitz M, Willis L. A new ELISA assay demonstrates sex differences in the concentration of serum polysialic acid. 2020, Analytical Biochemistry.
- Walia J. Liver transplantation for Gaucher disease presenting as neonatal cholestasis: Case report and literature review. 2020, Pediatric Transplantation.
- Strynadka N. Structure of the Peptidoglycan Synthase Activator LpoP in Pseudomonas aeruginosa. 2020, Structure.
- Brockhausen I. Inhibition of bacterial growth and galactosyltransferase activity of WbwC by α, ω-bis(3-alkyl-1H-imidazolium)alkane salts: Effect of varying carbon content. 2020, Bioorganic & Medicinal Chemistry.
- Guo T, Chakraberty R, Cairo C. Isoenzyme-Selective Inhibitors of Human Neuraminidases Reveal Distinct Effects on Cell Migration. 2020, ACS Chemical Biology.
- St-Pierre G, Rancourt A, Sato S. Metazoan Soluble β-Galactoside-Binding Lectins, Galectins: Methods for Purification, Characterization of Their Carbohydrate-Binding Specificity, and Probing Their Ligands. 2020, Methods in Molecular Biology.
- Shoichet M. Inverse Electron-Demand Diels-Alder Methylcellulose Hydrogels Enable the Co-Delivery of Chondroitinase ABC and Neural Progenitor Cells. 2020, Biomacromolecules.
- Brumer H. Synergy between Cell Surface Glycosidases and Glycan-Binding Proteins Dictates the Utilization of Specific Beta(1,3)-Glucans by Human Gut Bacteroides. 2020, mBio.
- Perreault H. Mass spectrometric analysis of core fucosylation and sequence variation in a human-camelid monoclonal antibody. Molecular Omics, 2020.
- Burnett A, Weadge J. The Escherichia coli cellulose synthase subunit G (BcsG) is a Zn2+-dependent phosphoethanolamine transferase. Journal of Biological Chemistry, 2020.
- Ovchinnikova O, Lowary T, Kimber M, Whitfield C. A bifunctional O-antigen polymerase structure reveals a new glycosyltransferase family. Nature Chemical Biology, 2020.
- Snarr B, Lehoux M, Sheppard D. What Are the Functions of Chitin Deacetylases in Aspergillus fumigatus? 2020, Frontiers in Cellular and Infection Microbiology.
- Deen M, Shen D, Vocadlo D. Selective fluorogenic β-glucocerebrosidase substrates for convenient analysis of enzyme activity in cell and tissue homogenates. 2020, ACS Chemical Biology.
- Lowary T. The endogenous galactofuranosidase GlfH1 hydrolyzes mycobacterial arabinogalactan. 2020, Journal of Biological Chemistry.
- Vocadlo D, Deen M, Tan HY, Shen D. A direct fluorescent activity assay for glycosyltransferases enables convenient high-throughput screening: Application to O-GlcNAc Transferase. 2020, Angewandte Chemie International Edition.
- LeMauff F. Exopolysaccharides and Biofilms. 2020, Current Topics in Microbiology and Immunology.
- Vinogradov E. A cell wall-associated polysaccharide is required for bacteriophage adsorption to the Streptococcus thermophilus cell surface. 2020, Molecular Microbiology.
- Zhu JS, Jakeman D. A missense variant remote from the active site impairs stability of human phosphoglucomutase 1. 2020, Journal of Inherited Metabolic Disease.
- MacLachlan M. Iridescent Cellulose Nanocrystal Films Modified with Hydroxypropyl Cellulose. 2020, Biomacromolecules.
- Wang W, Sychantha D, Wright G. Evolution-guided discovery of antibiotics that inhibit peptidoglycan remodelling. 2020, Nature.
- Vinogradov E, Logan S. In vitro Production and Immunogenicity of a Clostridium Difficile Spore-Specific BclA3 Glycopeptide Conjugate Vaccine. 2020, Vaccines.
- Zandberg W. 3D biofilms: in search of the polysaccharides holding together lichen symbioses. 2020, FEMS Microbiology Letters.
- Pshezhetsky A. Brain Pathology in Mucopolysaccharidoses (MPS) Patients with Neurological Forms. 2020, Journal of Clinical Medicine.
- Castagner B. Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers. 2020, Nature Communications.
- Dostie S, Prévost M, Nemer M, Guindon Y. Identification of a C3'-nitrile nucleoside analogue inhibitor of pancreatic cancer cell line growth. 2020, Bioorganic & Medicinal Chemistry Letters.
- Lehoux M, Howell PL, Sheppard D. Reducing Aspergillus fumigatus Virulence through Targeted Dysregulation of the Conidiation Pathway. 2020, mBio.
- Schweizer F, Arthur G. Syntheses of L-Rhamnose-Linked Amino Glycerolipids and Their Cytotoxic Activities against Human Cancer Cells. 2020, Molecules.
- Zandberg W. Influence of sulfonated and diet-derived human milk oligosaccharides on the infant microbiome and immune markers. 2020, Journal of Biological Chemistry.
- Pshezhetsky A. Molecular Bases of Neurodegeneration and Cognitive Decline, the Major Burden of Sanfilippo Disease. 2020, Journal of Clinical Medicine.
- Rini J. Trimeric HIV-1 gp140 fused with APRIL, BAFF, and CD40L on the mucosal gp140-specific antibody responses in mice. 2020, Vaccine.
- Vinogradov E. Antibody Binding to the O-Specific Antigen of Pseudomonas aeruginosa O6 Inhibits Cell Growth. 2020, Antimicrobial Agents and Chemotherapy.
- Morrison Z, Nitz M. TBAF Effects 3,6-Anhydro Formation from 6-O-Tosyl Pyranosides. 2020, Organic Letters.
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