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The latest news, publications and events from Canadian Blood Services’ Medical Affairs and Innovation research and education network.
Collected from May 2020

We hope this newsletter finds you safe and healthy. 

We welcome your feedback and encourage you to let us know what you would like to see in upcoming editions. Please share your comments and questions with us at centreforinnovation@blood.ca  

Upcoming events

Webinar series: Psychological First Aid, Grief and Loss, and Moral Distress in response to COVID-19 Part 3: Moral Distress During COVID-19   |  June 2, 2020 

LearnTransfusion Series: U of T Rounds: CBS Inventory/Future 
June 18, 2020 | Toronto/Webinar 

LearnTransfusion Series: Topic Teaching: New TRALI criteria 
June 23, 2020 | Toronto/Webinar 

Postponed: 
36th International Congress of the ISBT scheduled to take place in Barcelona in June 2020 has been postponed. 

View all events

New resources

COVID-19 resources

Other educational resources: 


Deceased organ donor management: clinical tools and resources  National data reports for Canadian Blood Services' interprovincial organ sharing programs:  Canadian Eye and Tissue Data Committee report:

Best Practices: 

Kudos 

Congratulations to Canadian Blood Services' Dr. Alan Lazarus who has been awarded the 2020 Ortho Award by the Canadian Society for Transfusion Medicine (CSTM) for his work to understand the mechanism of action of IVIg in disease. You can read more about Dr. Lazarus’ work and the Ortho Award in our May 26 R.E.D. Blog: Canadian Blood Services scientist Alan Lazarus honoured by the Canadian transfusion community

Funding opportunities from
Canadian Blood Services 

 
Supporting innovative research to improve the efficient and appropriate utilization of blood products. 
Application deadline: July 17, 2020
 
Salary support for young investigators.
Application deadline: July 17, 2020

Funding recipients 


Congratulations to all recently announced funding recipients!

      MSM Plasma Research Program:
  • Dr. William Fisher and Dr. Jennie Haw (Western University and Canadian Blood Services) 
  • Dr. Jacqueline Gahagan (Dalhousie University) 
  • Dr. Justin Presseau (Ottawa Hospital Research Institute) 
  • Dr. Joanne Otis (Université de Québec à Montréal) 

In the news

New publications

Each month we feature recent publications from the Canadian Blood Services’ research and education network. At the heart of this network are our staff scientists and medical experts, whose expertise range from microbiology to immunology, coagulation to cryopreservation, hematopathology to anesthesiology and much more. Learn more about Our Research Team.
 

Comparative Seasonalities of Influenza A, B and 'Common Cold' Coronaviruses - Setting the Scene for SARS-CoV-2 Infections and Possible Unexpected Host Immune Interactions 
Liu Y, Lam TTY, Lai FYL, Krajden M, Drews SJ, Hatchette TF, Fraaij PLA, van Kamen JJA, Badarch D, Nymadawa P, Tee KK, Lee HK, Koay ESC, Jennings L, Koopmas M, Tang JW. J Infect. 2020;S0163-4453(20)30243-7. [published online ahead of print, 2020 Apr 29] doi:10.1016/j.jinf.2020.04.032.  PMID: 32360499  

Current Techniques and the Future of Lung Preservation 
Lautner LJ, Freed DH, Nagendran J, Acker JP. Cryobiology. 2020;S0011-2240(20)30135-8.[published online ahead of print, 2020 Apr 29] doi:10.1016/j.cryobiol.2020.04.009. PMID: 32361000  

Transfusion-transmitted and Community-Acquired Cytomegalovirus: Infection in Seronegative Solid Organ Transplant Recipients Receiving 
Mabilangan C, Burton C, Nahirniak S, O'Brien S, Preiksaitis J. Am J Transplant. 2020;10.1111/ajt.16066. doi:10.1111/ajt.16066.[published online ahead of print, 2020 May 19]. PMID: 32428296 

Vox Sanguinis International Forum on Donor Incentives: Summary 
Zeller MP, Ellingham D, Devine D, Lozano M, Lewis P, Zhiburt E, van der Linde L, Goldman M, Nakamura A, Inoue S, Takikawa M, Nakajima K, Turek P, Řeháček V, Sakashita AM, Kutner JM, Karim FA, Hindawi S, Jayasekara SBA, Merz EM, Gross S, Woimant G, Djoudi R, Byabazaire KD, Irving DO, Abdrakhmanova S, Khalykova A, Yilmaz S, Örűç NE, Huaynalaya IP, Ramirez LAS, Chuhriiev A.  Vox Sang. 2020;115(4):339‐344. doi:10.1111/vox.12868. PMID: 32394471  

Vox Sanguinis International Forum on the Selection and Preparation of Blood Components for Intrauterine Transfusion: Summary 
Clarke G, Bodnar M, Lozano M, Nadarajan VS, Lee C, Baud D, Canellini G, Gleich-Nagel T, Torres OW, Rey PL, Bub CB, Kutner JM, Castilho L, Saifee NH, Delaney M, Nester T, Wikman A, Tiblad E, Pierelli L, Matteocci A, Maresca M, Maisonneuve E, Cortey A, Jouannic JM, Fornells J, Albersen A, Haas, MD, Oepkes D, Lierbman L. Vox Sang. 2020;10.1111/vox.12901. [published online ahead of print, 2020 May 12]. doi:10.1111/vox.12901. PMID: 32400093  

Utilising Red Cell Antigen Genotyping and Serological Phenotyping in Sickle Cell Disease Patients to Risk-Stratify Patients for Alloimmunisation Risk 
Shih AW, Yan MTS, Elahie AL, Barty RL, Liu Y, Berardi P, Azzam M, Siddiqui R, Parvizian MK, Mcdougall T, Heddle NM, Al-Habsi KS, Goldman M, Cote J, Athale U, Verhovsek MM. Transfus Med. 2020;10.1111/tme.12685. [published online ahead of print, 2020 May 20]. doi:10.1111/tme.12685. 

Variability in deceased donor care in Canada: a report of the Canada-DONATE cohort study. 
D'Aragon F, Lamontagne F, Cook D, Dhanani S, Keenan S, Chassé M, English S, Burns KEA, Frenette AJ, Ball I, Boyd JG, Masse MH, Breau R, Akhtar A, Kramer A, Rochwerg B, Lauzier F, Kutsogiannis DJ, Ibrahim Q, Hand L, Zhou Q, Meade MO; Canadian Critical Care Trials Group and the Canadian Donation and Transplant Research Program. Can J Anaesth. 2020 May 8. doi: 10.1007/s12630-020-01692-7.  PMID: 32385825  

Venous limb gangrene and pulseless electrical activity (PEA) cardiac arrest during management of deep-vein thrombosis and progressive limb ischemic necrosis following vascular surgery. 
Avram AT, Blostein MD, Hirsch AM, Warkentin TE. Am J Hematol. 2020 Jun;95(6):712-7. doi: 10.1002/ajh.25768. Online ahead of print. PMID: 32112441 

GRADE Guidelines 28: Use of GRADE for the assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks
Foroutan F, Guyatt G, Zuk V, Vandvik PO, Alba AC, Mustafa R, Vernooij R, Arevalo-Rodriguez I, Munn Z, Roshanov P, Riley R, Schandelmaier S, Kuijpers T, Siemieniuk R, Canelo-Aybar C, Schunemann H, Iorio A. J Clin Epidemiol. May 2020; 121:62-70. doi: 10.1016/j.jclinepi.2019.12.023. Online ahead of print. PMID: 31982539 

Increased cytotoxic potential of CD8+ T cells in immune thrombocytopenia. 
Vrbensky JR, Arnold DM, Kelton JG, Smith JW, Jaffer AM, Larché M, Clare R, Ivetic N, Nazy I. Br J Hematol. 2020 Mar;188(5):e72-e76. doi: 10.1111/bjh.16334. Online ahead of print. PMID: 31850531    

Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion
Heddle NM, Cardoso M, van der Meer PF. Transfusion. 2020 May 6. doi: 10.1111/trf.15779. [Epub ahead of print] PMID: 32378230  

A crosswalk tabular review on methods and outcomes from randomized clinical trials using pathogen reduced platelets. 
Rebulla P, Graban F, van der Meer PF, Heddle NM, McCullough J. Transfusion. 2020 Apr 23. doi: 10.1111/trf.15791 [Epub ahead of print]  PMID: 32324294  

Platelet Factor 4 Interactions with Short Heparin Oligomers: Implications for Folding and Assembly
Niu C, Yang Y, Huynh A, Nazy I, Kaltashov IA.  Biophys J. 2020 Apr 21. doi: 10.1016/j.bpj.2020.04.012 [Epub ahead of print]  PMID: 32348723  

HIT: still stringing us along. 
Warkentin TE. Blood. 2020 Apr 9;135(15):1193-4. doi: 10.1182/blood.2020005157   PMID: 32271906  

Combination of two complementary automated rapid assays for diagnosis of heparin-induced thrombocytopenia (HIT). 
Warkentin TE, Sheppard JI, Smith JW, Li N, Moore JC, Arnold DM, Nazy I. J Thromb Haemost. 2020 Mar 13. doi: 10.1111/jth.14794 [Epub ahead of print] PMID: 32167669  

  

 Search our publications database on blood.ca 

 

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Developed in collaboration with Canadian Blood Services' Centre for Innovation. Please share your feedback with centreforinnovation@blood.ca

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