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CRE Network Newsletter #17 - September 2019
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The CRE is an NHMRC funded venture between two of the leading hubs in stroke research in Australia - The Florey Institute of Neuroscience and Mental Health in Heidelberg and the Hunter Medical Research Institute in Newcastle.

SSA 2019

Our researchers put on a great show of their research in Canberra at SSA recently. There were many presentations ranging from pre-clinical work, therapy dose, the Stroke Recovery Roundtable through to data linkage projects. We were pleased that they also scooped a number of awards.
Prof Julie Bernhardt was presented with the SSA mentor award at the gala dinner in Parliament House. Dr Liz Lynch won the New Investigator Award, Dr Charlotte Ermine received a SSA Bursary Award and Dr Andrew Bivard was awarded the SSA-Boehringer Ingelheim Acute Stroke Research Innovation Grant.
Top left (l-r): Dr Marie-Louise Bird, Dr Liz Lynch (front), Dr Erin Godecke, Prof Dominique Cadilhac, Prof Julie Bernhardt, Nat Fini, Dr Sharon Kramer
Top right: Prof Julie Bernhardt with her SSA mentor award
Bottom left: Lady Lynne Cosgrove, General Sir Peter Cosgrove, Prof Julie Bernhardt
Bottom right: Dr Liz Lynch with her New Investigator Award

Event and seminar dates


16 October
Optimising Health Environments, Melbourne

28 and 29 October
International Stroke Recovery and Rehabilitation Alliance (ISRRA) meeting, Geelong

30 October
ISRRA Stroke Showcase - World leading research and an opportunity to meet the researchers, The Florey, Heidelberg

28 November
National Stroke Data and Quality Improvement Workshop, Sydney

29 November
CRE Seminar: Kate Hayward

10 December
CRE Consumer Forum, The Florey, Heidelberg

6th Optimising Health Environments Forum, Parkville
Wednesday, 16 October

The 6th Optimising Health Environments forum promises to be a great day showcasing research in that space.

The aim of this one-day forum is to bring together individuals from a range of backgrounds with an interest in health environments to share knowledge and build collaborative links. Registration is free and includes morning tea, lunch and afternoon tea.
 
DATE/TIME: Wednesday, 16 October 2019, 8:30am (registration) – 5:00pm
 
LOCATION: Ian Potter Auditorium, Ground Floor, Kenneth Myer Building
The Florey, Melbourne Brain Centre, The University of Melbourne
30 Royal Parade, Parkville, 3052
                               
REGISTRATION: Register via this link

RSVP: 5pm on Monday, 7 October

If you require any further information or have any questions, please feel free to email Sarah-May Blaschke


To read the program click here.

SSA 2019 Pre-Conference Rehab Day
10 September

Our Rehab Day on Tuesday 10 September in Canberra went very well (apart from a few technical hitches). With the topic of 'New Frontiers in Stroke Rehabilitation and Recovery' our line-up of speakers included Prof Miranda Rose and Dr Pamela Duncan. There were 82 people registered to attend.
You can catch the highlights on Twitter moments:

Dr Pam Duncan
Dr Annie Hill and Prod Chris Bladin
Dr Brooke Ryan, Dr Rachelle Pitt, Dr Viv Fu, Dr Emma Power

In 2020 the SSA conference will be in Perth in 2020 and it will be the 30th scientific meeting. Put the date in your diary now. Look out for another pre-conference Rehab Day.

Date: 8 to 11 September 2020.

Access Anywhere - Recordings now available

Our Access Anywhere Stroke Tele-Rehab Day can now be viewed on our Facebook page and on YouTube (Part 1 and Part 2).

A/Prof David Clarke Seminar recording

The recording of A/Prof David Clarke's early August seminar is available for viewing on YouTube. The title of the seminar was Co-production - on trend or adding value? A/Prof Clarke is from Leeds University (UK) and was in Australia to speak at Smart Strokes as an invited speaker.

PhD Opportunity at University of Melbourne

Photo by Good Free Photos on Unsplash
A PhD opportunity is available for either a full time or part time domestic PhD candidate at the University of Melbourne.

Topic: Physical activity for glycaemic control and bone mass after stroke

Outline: Poor glycaemic control and accelerated bone loss contribute to the development of diabetes, secondary stroke and heightened risk of bone fracture after stroke. Promisingly, weight bearing exercise and reduction in sedentary time are associated with reduced bone loss and improved glycaemic control within the first 6 months of stroke.

This PhD project will focus on developing and piloting a multisite physical activity program to address these issues in people with stroke, to support the development of clinical guidelines. You will be working as part of a dynamic research team across The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australian Institute of Musculoskeletal Science (AIMSS), Western Health and St Vincent’s Hospital Melbourne.

This project is also supported by a national collaboration of researchers and clinicians (including the “ACTivity to Improve Outcomes after Stroke [ACTIOnS]” collaboration).

Supervisors: Associate Professor Cathy Said, Associate Professor Elif Ekinci and Dr Karen Borschmann.

Eligibility:
  • Physiotherapist or Accredited Exercise Physiologist with relevant clinical experience – ideally in stroke.
  • The successful applicant must also meet eligibility requirements for enrolment in University of Melbourne Research Higher Degree.

Scholarship: A student stipend is available, $31200 (tax free) for one year full time or $15,600 (taxed) for 2 years part time, with the expectation that the candidate will be competitive to seek further scholarship opportunities.

Further information: Please contact A/Prof Cathy Said for further information.

To apply: Click here for details.

PhD Opportunity at University of Tasmania

Fitness and Mobility Exercise after stroke – A scalable national approach
 
We are looking for a PhD student for this funded project to work with Dr Marie-Louise Bird and a team of clinician scientists in stroke recovery and rehabilitation.
 
This project would suit a health professional with a clinical qualification. The project is based in the School of Health Sciences, University of Tasmania at the Launceston campus. The successful applicant would be expected to be located in Tasmania for data collection within one year of starting the PhD.
 
There is opportunity to apply for a scholarship for a full-time student who can enroll before the end of the year. Funds to carry out the project have been secured.
 
Aims and Objectives:
The overall aim of this research is to improve our understanding of facilitators and barriers to the scaling-up the delivery of evidence-based community exercise programs for those living with stroke. This is part of a staged series of work that has specific objectives to:
  • Provide and evaluate a cascading style of training of physiotherapist or exercise physiologist and fitness instructor pairs in six different communities across Australia and evaluate the effectiveness of this training on subsequent scale-up of programs.
  • Conduct an implementation evaluation of the exercise programs that communities run.
  • Assess health and other outcomes of community participants in the exercise programs.
 
Please contact Dr Marie-Louise Bird if you would like more information on the project or information on putting in an expression of interest.

Second Stroke Recovery and Rehabilitation Roundtable - publications out soon

More Stroke Recovery and Rehabilitation Roundtable (SRRR) papers will be out soon. 

In Geelong, the International Stroke Recovery and Rehabilitation Alliance will meet in October. The aim of the ISRRA meeting is to build partnerships and make plans to progress the important work of the SRRR.

MIDAS2 (Modafinil in Debilitating Fatigue
After Stroke 2) (repeat entry)

 
The phase III MIDAS2 trial  is now underway and has been enrolling participants for just over a year!

The trial was initially opened at 3 centres:  The Royal Adelaide Hospital (SA), Royal Melbourne Hospital – City campus (Parkville, Victoria) and John Hunter Hospital – New Lambton (NSW). However, there are now 14 participating centres nationally.
MIDAS2 has a target of 300 participants and is recruiting actively across the Australia.
 
MIDAS2 is a Multicentre, prospective, randomised, placebo controlled, double-blind, parallel group phase III trial with an adaptive sample size re-estimation in stroke survivors enrolled 3 or more months  after their event. The primary objective is to test the hypothesis that in stroke survivors, 200mg of modafinil taken once daily for at least 56 days significantly improves participant quality of life compared to placebo, due to the improvement of severe and persisting fatigue after stroke.
If you have seen a patient who meets the below criteria, they may be eligible for the MIDAS2 trial:
  1. Has had a STROKE at least 3 months ago,
  2. Has severe, persistent and debilitating FATIGUE and
  3. Has a modified Rankin Scale (mRS) < 3
You can access more information about the study on ANZCTR or here, or contact one of the study researchers Dr Andrew Bivard by email.
This study is being supported by The Greater Charitable Foundation.

Re-imagining Stroke Environments with Virtual Reality (RiSE-VR)
Research Participants needed (repeat entry)

Photo by JESHOOTS.COM on Unsplash
Michelle Shannon, a PhD student at The Florey, is seeking research participants for a virtual reality study.

This project is examining how responses and behaviours of stroke survivors can be influenced by hospital ward physical environment. There is limited scientific knowledge informing the design of hospital environments for people who have had a stroke. You are eligible for this study if you have had a stroke and are discharged from hospital at least 1 month.

Researchers from The Florey Institute and Swinburne University are exploring the responses of stroke survivors to a novel patient room design immersive virtual reality experience (VR).

Participation involves completing 2 VR sessions lasting 60 minutes each, and answering some questionnaires. This will be followed by a single interview with you to gather further details from you about the VR experience.

Researchers will measure your responses using preference and emotional ratings while using the VR experience. Your physical responses will also be tracked using a pulse and blood pressure probe, and a wearable motion sensor. This study will run for 2 years at The Florey Institute, Melbourne.

If you are interested in participating in the study please email Michelle.

Researchers are seeking health professionals to provide their views on discharge planning for stroke survivors (repeat entry)

Dear Stroke Clinician,
 
We need your help in answering our research question!
 
What is current practice amongst Australian healthcare professionals of coordinated discharge planning for people who have had a stroke?
 
Going home after a stroke is a significant milestone in the stroke recovery journey.  To transition home successfully, patient-centred discharge planning is essential and results in reduced anxiety and depression, improved satisfaction with health care, continuity of care and general wellbeing. Successful discharge planning also improves compliance with community-based rehabilitation, and reduces length of stay, risk of rehospitalisation following discharge and risk of secondary stroke. As such, the provision of a stroke discharge care plan is recommended internationally in stroke clinical guidelines and standards. Ideally this process should be coordinated between acute and specialist care providers and primary care.
Our study aims to determine healthcare professionals’ knowledge, confidence and satisfaction in coordinated discharge planning post stroke and perceived barriers and facilitators in current practice.
 
If you are interested in participating, please click on the link below to access the SurveyMonkey survey.  Once you open the link you will be able to provide consent before completing the survey.
 
https://scuau.qualtrics.com/jfe/form/SV_4GBPqtCUXUb9CoR
 
Participation in this project is entirely voluntary. The project has received ethical clearance from The University of Queensland and Southern Cross University.
 
We would also appreciate if you could forward this onto any colleagues currently working with people who have had a stroke in any setting, who you think might be interested in participating in this project.
 
If you have any questions, I can be contacted on +61 7 3413 7687 or r.pitt1@uq.edu.au.
 
Kind regards,
 
Dr Rachelle Pitt

Victorian Stroke Telemedicine

The Victorian Stroke Telemedicine (VST) service launched their  new educational resources during Stroke Week (2 - 8 September).

Tele-etiquette, or web-side manner, is a set of standards to consider when using telemedicine for clinical consultations.

VST has produced a short video which highlights the key concepts of tele-etiquette we feel are important: Environment; Technology; Appearance and Communication (ETAC).

When using telemedicine in your clinical practice, ask yourself, "Are you ETAC ready?"

Find out more about VST at their website. Recently they treated their 5000th patient. An amazing milestone.

Towards an integrated national data platform for stroke

Monique Kilkenny will be speaking about the innovative national stroke data linkage program. She is driving this program that links data from the Registry with administrative data across the continuum of stroke care. This will enable an integrated national data platform for stroke. Monique is a Senior Research fellow/NHMRC Research Fellow within the Stroke & Ageing Research Group (Monash University). She is an emerging leader in stroke and collaborates with other leaders in the field of stroke research. Her expertise is particularly recognised in her expertise for analysing large and complex datasets.

When
Wednesday, 25 September, 2019 12:00 PM - 12:40 PM AEST
Where: Via webinar
Registration: https://register.gotowebinar.com/register/2825500092835417100

HMRI Open Day
11 October 2019, 10am to 3pm

HMRI have been busy planning to make this year even bigger and better than before. This is your chance to see what goes on behind the lab doors, meet their incredible researchers and find out what research is happening in Newcastle.
  • We have something for everyone with attractions including:
  • Hands-on Health and Medical Research Expo
  • Interactive Science Sessions and Activities
  • Science Meets Fiction Talk
  • Laboratory Tours
  • Research and Discovery Public Seminars
  • And much more.....
Free shuttle buses are running all day from McDonald Jones Stadium and we have a range of food and drink available for the duration of the event. The HMRI cafe and BBQ will be serving from 10am to 3pm on Level 4. Don't forget to wear your comfortable shoes and clothes, bring your water and hat - and get set for a huge day!

Find out more and register here.
You are invited to register for Seminar # 3
 
Who benefits, and why? Person-specific and practice-related predictors of naming treatment response in aphasia
Presentation by Associate Professor Mike Dickey, Department of Communication Science and Disorders University of Pittsburgh, USA
 
DATE: Wednesday 25 September 2019
TIME: 3.00 -4.00pm(AEST) (presentation)
TIME: 4.00 -4.30pm (network opportunity)
 
VENUES:
  • La Trobe University, Bundoora Campus, HS1-203, (Health Sciences 1, Level 2, Room 203)
  • Zoom event from The University of Sydney, Cumberland Campus N block, Room N104
  • Remote attendees: Webinar link provided on registration (Limited to 100 connections)
RSVP essential - Register here
 
Previous Seminar Recordings
Seminar 1 & 2 recordings are available on the Aphasia CRE website
If you attended Seminar 2 with Prof Sabine Corsten, all Slido questions were answered and added to the end of the Seminar 2 recording.

World Stroke Day - 29 October 2019

For World Stroke Day the World Stroke Organisation will launch their #DontBeTheOne campaign. Find out more about how this campaign supports their ambitious stroke prevention strategy in The Lancet editorial.
'The WSO campaign will use a three-pronged approach. First, to raise awareness and allow self-assessment and monitoring of stroke risk. Second, to encourage adoption of a polypill (with generic low-dose blood pressure and lipid lowering medications) in people at high risk. And third, to engage health professionals to help tackle modifiable risk factors.'
People will be encouraged to use the mobile phone app - Stroke Riskometer™ to determine their risk of stroke.
EDITORIAL, Global prevention of stroke: focus on the individual?, The Lancet Neurology, (2019), 18(10);903. doi.org/10.1016/S1474-4422(19)30317-5

Stride 4 Stroke

Stride4Stroke is the Stroke Foundation’s signature event, where we encourage our community to get active during the month of November and help prevent, treat and beat stroke. Simply pick an activity, set your personal goal and complete it anytime between 1 to 30 November.
Find some friends and raise money for this great organisation.
Be part of this unique collaboration as ESO and WSO join forces to try to improve stroke care globally. Submit your work and present it at the largest stroke conference to date.

Submission guidelines and abstract topics can be found on our website.

Abstract Submission Deadline: 15 January 2020 
PROGRAM ANNOUNCED - 7th NATIONAL BRAIN INJURY CONFERENCE

Held in partnership with the Melbourne Disability Institute, Brain Injury Australia has released the program for its 7th National Brain Injury Conference.
When: Monday 28 and Tuesday 29 October 2019
Where: Melbourne School of Design on The University of Melbourne's Parkville campus
Early Bird: Before Thursday 26 September

The Conference includes presentations and panel discussions devoted to: 
  • breakthroughs in neurotrauma research; 
  • concussion and “mild” traumatic brain injury (TBI); 
  • brain injury in Aboriginal and Torres Strait Islander communities; 
  • TBI and "challenging behaviours"; 
  • what works in cognitive rehabilitation; 
  • people with a brain injury and the criminal justice system; 
  • domestic and family violence and brain injury; 
  • inflicted TBI in children/ “shaken baby syndrome”; 
  • helmets - their efficacy, innovations in design and materials; and
  • employment for people with a brain injury.
Click here to register.

View the full conference program here.

International Year of Indigenous Languages

From over in the west we have some words from the indigenous Noongar people. To find out more about their language click here.

Yonga – Kangaroo
Weitj – Emu
Ngarniny – Eat, Eating
Ngarngk – Mother, sun
Ke-ning/Ke-niny – Dance
Kedalak – Night time
Kedalup – Daytime
Keip/Kep/Keipa – Water (fresh)

2019 is the International Year of Indigenous Languages.


Radio National has a 'Word Up' project that 'shares the diverse languages of black Australia from Anmatyerre to Arrernte, from Bidjara to Bundjalung, from Nyungar to Ngaanyatjarra, from Yankunytjatjara to Yorta Yorta—one word at a time.'

Facebook 

On Facebook we have 328 followers. Click here to keep up to date with the CRE's activities and research. Also hear about the stroke theme at The Florey.

Twitter (@strokeCRE)

Twitter is a terrific way to keep up to date with stroke research. Find us here. Since our last network newsletter we have added over 200 more followers and total 2,842 followers.

Publications

Our publications are added regularly to the CRE's website. View them all on our publications page.
Wendy Hendrickx, Carlos Riveros, Torunn Askim, Johannes B.J. Bussmann, Michele L. Callisaya, Sebastien F.M. Chastin, Catherine M. Dean, Victor E. Ezeugwu, Taryn M. Jones, Suzanne S. Kuys, Niruthikha Mahendran, Trish J. Manns, Gillian Mead, Sarah A. Moore, Lorna Paul, Martijn F. Pisters, David H. Saunders, Dawn B. Simpson, Zoë Tieges, Olaf Verschuren & Coralie English (2019) Identifying factors associated with sedentary time after stroke. Secondary analysis of pooled data from nine primary studiesTopics in Stroke Rehabilitation, 26:5, 327-334, DOI: 10.1080/10749357.2019.1601419

Toby B. Cumming, Leonid Churilov, Janice Collier, Geoffrey Donnan, Fiona Ellery, Helen Dewey, Peter Langhorne, Richard I. Lindley, Marj Moodie, Amanda G. Thrift, Julie Bernhardt, on behalf of the AVERT Trial Collaboration group (2019). Early mobilization and quality of life after strokeNeurology  93 (7) e717-e728; DOI:10.1212/WNL.0000000000007937

Sarah R. Valkenborghs, Robin Callister, Milanka M. Visser, Michael Nilsson & Paulette van Vliet (2019) Interventions combined with task-specific training to improve upper limb motor recovery following stroke: a systematic review with meta-analysesPhysical Therapy Reviews, DOI: 10.1080/10833196.2019.1597439

Hayward KS, Kramer S, Thijs V, Ratcliffe J, Ward NS, Corbett D, Jolliffe L, Brodtmann A, Cloud G, Kaffenberger T, Bernhardt J, Lannin NA (2019). A systematic review protocol of timing, efficacy and cost effectiveness of upper limb therapy for motor recovery post-strokeBMC Systematic Reviews, 8, 187. doi: 10.1186/s13643-019-1093-6

Samantha Robertson, Rohan Grimley, Chris Anstey and Ingrid Rosbergen (2019) Acute stroke patients not meeting their nutrition requirements: Investigating nutrition within the enriched environmentClinical Nutrition, DOI: 10.1016/j.clnu.2019.06.009

Shannon Taylor Sarah Jane Wallace Sarah Elizabeth Wallace (2019) High-Technology Augmentative and Alternative Communication in Poststroke Aphasia: A Review of the Factors That Contribute to Successful Augmentative and Alternative Communication Use
Perspectives of the ASHA Special Interest Groups, 4 (3):464-473 DOI: 10.1044/2019_PERS-SIG2-2018-0016

Sanchez Bezanilla, S., Nilsson, M., Walker, F. R., & Ong, L. K. (2019) Can We Use 2,3,5-Triphenyltetrazolium Chloride-Stained Brain Slices for Other Purposes? The Application of Western BlottingFront. Mol. Neurosci. 12:181. DOI: 10.3389/fnmol.2019.00181

Sanchez Bezanilla, S., TeBay, C., Nilsson, M., Walker, F. R., & Ong, L. K. (2019) Visual discrimination impairment after experimental stroke is associated with disturbances in the polarization of the astrocytic aquaporin-4 and increased accumulation of neurotoxic proteins. Exp. Neurol. 318, 232–243. DOI: 10.1016/j.expneurol.2019.05.001

Peter Goodin, Gemma Lamp, Rishma Vidyasagar, et al. (2019) , “Correlated Resting-State Functional MRI Activity of Frontostriatal, Thalamic, Temporal, and Cerebellar Brain Regions Differentiates Stroke Survivors with High Compared to Low Depressive Symptom ScoresNeural Plasticity, vol. 2019, Article ID 2357107, 12 pages, DOI: 10.1155/2019/2357107

Wallace, S.J., Baker, C., Brandenburg, C., Bryant, L., Le Dorze, G., Power, E., . . . Trebilcock, M. (2019). A how-to guide to aphasia services: celebrating Professor Linda Worrall’s contribution to the fieldAphasiology, 33(7), 888-902. DOI: 10.1080/02687038.2019.1609774

Menn, L., Corsten, S., Lauer, N., & Wallace, S. J. (2019). The Effectiveness of Biographical Approaches in Long-Term Care: A Systematic ReviewThe Gerontologist. DOI: 10.1093/geront/gnz074

Denham AMJ, Guillaumier A, McCrabb S,...Spratt NJ, Pollack M,...Callister R,...et al (2019).
Development of an online secondary preention programme for stroke survivors: Prevent 2nd StrokeBMJ Innovations DOI: 10.1136/bmjinnov-2017-000257

Lipson-Smith, R., Churilov, L., Newton, C., Zeeman, H., & Bernhardt, J. (2019). A framework for designing inpatient stroke rehabilitation facilities: a new approach using interdisciplinary value-focused thinkingHealth Environments Research and Design Journal, 1-17. doi:10.1177/1937586719831450

Bernhardt, J., Borschmann, K. N., Kwakkel, G., Burridge, J. H., Eng, J. J., Walker, M. F., Bird, M.-L., Cramer, S. C., Hayward, K. S., O'Sullivan, M. J., Clarkson, A. N., Corbett, D., & for the SRRR2 Collaboration. (2019). Setting the scene for the Second Stroke Recovery and Rehabilitation RoundtableInternational Journal of Stroke. doi: 10.1177/1747493019851287

Gao, L., Sheppard, L., Wu, O., Churilov, L., Mohebbi, M., Collier, J., Bernhardt, J., Ellery, F., Dewey, H., Moodie, M., & The AVERT Trial Collaboration group. (2019). Economic evaluation of a phase III randomised controlled trial of very early mobilisation after stroke (AVERT)BMJ Open, 9, e026230. doi: 10.1136/bmjopen-2018-026230

Rethnam, V., Bernhardt, J., Dewey, H., Moodie, M., Johns, H., Gao, L., Collier, J., Ellery, F., Churilov, L., on behalf of AVERT Trial Collaboration group. (2019.) Utility-Weighted modified Rankin Scale: still too crude to be a truly patient-centric primary outcome measure? Int J Stroke. doi:10.1177/1747493019830583 (ePub 12 Feb 19)

Shipley, J., Luker, J., Thijs, V., & Bernhardt, J. (2019). How can stroke care be improved for younger service users? A qualitative study on the unmet needs of younger adults in inpatient and outpatient stroke care in AustraliaDisability & Rehabilitation. doi: 10.1080/09638288.2018.1534278 (ePub 7 Jan 19)

Tanya A. Rose, Sarah J. Wallace & Sibin Leow (2019) Family members’ experiences and preferences for receiving aphasia information during early phases in the continuum of care, International Journal of Speech-Language Pathology, DOI: 10.1080/17549507.2019.1651396

Can you help? 

Do you want to participate in research? Send us comments on our research? Want to join in CRE activities? Then stay on this mailing list.
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