UCSF CCMBM Cores: Featured Services

CCMBM Cores:
Featured Services

The Core Center for Musculoskeletal Biology & Medicine (CCMBM) defines itself by emphasizing musculoskeletal-specific events, grants, and services that are critical to its members but not available elsewhere in the university system.

ACKNOWLEDGING THE CCMBM

If you have received a CCMBM grant, formed a collaboration at one of our events, or used one of our cores, please acknowledge the CCMBM in related publications and presentations. We suggest stating:

Research reported in this publication was supported by the UCSF Core Center for Musculoskeletal Biology and Medicine (CCMBM) of the National Institute of Health's National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the award number P30AR066262 .

UPCOMING CCMBM EVENTS

CCMBM Tools and Technology Grant - Application deadline is November 18, 5:00pm.

Awards are up to $5,000 to encourage utilization or services available through the CCMBM Cores.

Research topics should be translational in nature within the musculoskeletal field. The goal of this grant mechanism is to encourage utilization of the many cutting-edge technologies or services now available through the CCMBM cores.

Priority will be placed on proposals requesting T/T funds to add the use of a new technology/ core service to an existing or recently-proposed project. Proposals requesting funds to support new project ideas should apply to the CCMBM Pilot and Feasibility Grant Program that will open in early 2020.

Specific Aims Review - Increase your chances of being funded for the next cycle of NIH R01 and K grants! Have CCMBM established investigators give you personalized feedback on your specific aims page that can help focus your aims and improve your overall application for funding opportunities.

Review appointments are limited and only available for CCMBM members (check if you are a member) at the following locations:

1. General sign up (Mission Bay, 1700 Owens)

2. Ortho-related sign up (Parnassus, Medical Sciences)

3. Radiology-related sign up (Mission Bay, Mission Hall)

CCMBM IMAGING CORE

There’s a new scanner in town! With support from the CCMBM, the Department of Radiology and Biomedical Imaging has purchased a new-generation in vivo human HR-pQCT scanner: the XtremeCT II. The XtremeCT II has increased spatial resolution, lower scan time, and the capability to scan the knee. These example images show the improved spatial resolution and the unprecedented high-res in vivo knee images produced by the XtremeCT II. The Imaging Core will be looking for research partners as this machine comes online – please contact us if you have a potential application for this new imaging tool! The XtremeCT II will be in place by January 2020. For more information, please contact Imaging Core Director, Galateia Kazakia at galateia.kazakia@ucsf.edu.

Figure 1. Sagittal view through the knee imaged on the XCT II (Courtesy of Manske et al, University of Calgary).

Figure 2. Images of a spatial resolution phantom obtained on the XCT I (A), the XCT II in “XCT I mode” (B), the XCT II at standard 61 µm voxel size (C), and the XCT II at high res 30 µm voxel size (D). (Courtesy of Steve Boyd, University of Calgary)

CCMBM EBSD CORE

Epi core consulting: Shovel Ready data sets? Do you have a data set that is ready for analysis? Perhaps a set of patients in your clinic? The Epi Core can provide help to turn your sow’s ear into a silk purse. We can provide data management help to clean the data and then work with you to provide analyses for your next abstract or paper. .
Through CTSI and Epi Core, we can provide up to 5-6 hours of help at no charge to CCMBM members. If you are interested, please contact Lucy Wu at Lwu@psg.ucsf.edu, for more information and an application form.

CCMBM SBB CORE

		Are you looking for routine chemical assay results from small animal samples? The Skeletal Biology Core now has a clinical Vet Axcel available for service. The Vet Axcel is capable of running up to 15 serum samples at a time, with tests that determine levels of calcium, phophorous, albumin, alkaline phosphatase, BUN, creatinine and magnesium. These results can be great supplemental data for researchers’ projects. The Vet Axcel requires 50µl of serum per sample to run the entirety of the assay panel.
If interested, please contact Nicolas Szeto, SBB Core Manager, at nicholas.szeto@ucsf.edu for more information.

ACKNOWLEDGING THE CCMBM