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Dear all,
Welcome to this first edition of our monthly newsletter with all updates and latest news regarding the SPOT-studies! The SPOT-studies aim to improve the care for women with preeclampsia in Ghana.
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SPOT-studies overview
- To externally validate the fullPIERS and miniPIERS prediction models, and develop a simple, user friendly, numeric Severe Pre-eclampsia adverse Outcome Triage (SPOT) score to assist clinical decision making in severe early pre-eclampsia (SPOT-VAL).
- To quantify the relationship between fetal (and maternal) APOL1 status and preeclampsia and assess whether this can predict pre-eclampsia (SPOT-BIO).
- To understand the views on ‘good care’ of various stakeholders in the care of Hypertension Disorders in Pregnancy (HDP): health professionals, health management and pregnant women themselves.
- To assess impact of SPOT-score combined with shared-decision making tool implementation (SPOT-impact).
SPOT-study Timeline
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Updates
SPOT-BIO coordinator Nana Ampofo: has successfully completed the Clinical Research Monitoring summer school in Utrecht, Netherlands.
Start Daily Krijnen: she joined our research group as coordinator and will be conducting her own substudy on mental health issues.
Start Mona Zeevaert: she recently joined the Cesarean section study group at Korle-Bu Teaching Hospital, and will support the normotensive cohort study activities as part of a collaboration between our two groups.
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News
SPOT-BIO launched in 3 hospitals: Greater Accra Regional Hospital, Korle-Bu Teaching Hospital and La General Hospital. Eastern Region Hospital Koforidua will start this week with recruitments.
Dutch Research Council Grant for SPOT-impact:
Research on Routes for Consortia (NWA-ORC) granted a total of €1.3 million to the SPOT-Impact study, which aims to develop a shared decision making tool for risk assessment for pregnant women with preeclampsia in Ghana.
Consortium members: UMC Utrecht, University of Amsterdam, Ghana Health Services, University of Ghana, Korle-Bu Teaching Hospital, University of Tennessee, University of British Columbia, Share-Net, FIGO, and the Action of Preeclampsia Ghana (APEC-GH)
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Recruitment process
Research assistants and nurses have been recruited and trained for the fetal sample collection and follow up in Ridge, Korle-Bu, La General and Koforidua.
SPOT-VAL: SPOT-BIO:
Ridge Hospital: 311 women 96 women
Korle Bu Teaching Hospital: 232 women 36 women
La General Hospital: 169 women 30 women
Lekma Hospital: 17 women
Tema Hospital: 41 women
Koforidua: 8 women 8 women
Total: 778 women
Almost there! Soon we will start with the recruitment of the control group which includes 1600 normotensive women.
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Ghana Health Services, Accra, Ghana
- Dr. Emmanuel K. Srofenyoh, MBChB MPhil FWACS
- Dr. Fred Pobee, MBChB FWACS
- Dr. Sylvia Deganus, MBChB MPH FWACS
- Dr. Hellen Akaba, MBChB MPH FWACS
- Dr. Ama Tamatey, MBChB FWACS
- Dr. Patrick Aboagye, MB-BCH MPH Dip. RH
- Dr. Kwame Anim-Boamah, MBChB MBA FWACS
- Prof. Dr. Irene Agyepong, MBChB PhD
- Dr. Evelyn K. Ansah, MBChB PhD
- Dr. Edward Antwi, MBChB PhD
- Dr. Maame Yaa Essel, MBChB
- Mr. Nana K.A. Ampofo, BSc
UMC Utrecht, The Netherlands
- Dr. Joyce Browne, MD PhD
- Prof. Dr. Diederick Grobbee, MD PhD FESC
- Dr. Kerstin Klipstein-Grobusch, PhD
- Prof. Dr. Arie Franx, MD PhD
- Ms. Ilja van der Geest, Ms. Tessa van Otterloo, Ms. Lisa Kraneburg, Ms. Connie Rees, Ms. Daily Krijnen, Ms. Mona Zeevaert
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Korle-Bu Teaching Hospital
- Dr. Kwame Adu-Bonsaffoh, MD MPhil FWACS, University of Ghana Medical School
University of British Columbia, Vancouver
University of Tennessee (APOL1 substudy)
- Dr. Claire Simpson, PhD
- Prof. Robert Davis, MD MPH
- Ms. Alana Tonya Smith, Sr. RA
H3Africa Kidney Network
(APOL1 substudy)
- Dr. Vincent Boima, MBChB
- Dr. Dwoama Adu, MBChB
- Dr. Charlotte Osafo, MBChB
University of Ghana, Noguchi
- Dr. Mary Amoakoh-Coleman, MBChB PhD
- Dr. Daniel Arhinful, PhD
- Dr. Hannah Brown Amoakoh (joint collaboration with UMCU)
University of Amsterdam
(Quality of care)
- Dr. Bregje de Kok, Dr. Trudie Gerrits, Ms. Asra Vestering
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