Editorial

Dear friends,

We begin this edition of our newsletter with a new article, written by the GMFH Editorial Board Coordinator, René van den Wijngaard, about the first study to clearly demonstrate the concept of keystone species in the context of reducing IBD risk through early-life interventions in genetically prone offspring.

Next up, Joël Doré and Andreu Prados highlight the most significant learnings from the 10th Gut Microbiota for Health World Summit, which took place on March 12 and 13 in Washington DC (USA), and how they might affect clinical practice in the foreseeable future.

You will also come across a new article that explores what we know so far about the role of the gut microbiota in diverticulitis and discusses two recent clinical trials on the role of probiotics in managing acute uncomplicated diverticulitis.

Finally, Prof. Ted Dinan from University College Cork (Ireland), met the GMFH team to talk about the evidence for the influence of the gut microbiota
on brain and behavior and potential gut microbiome-targeted interventions
that have benefits for mental health.

Happy reading!
The GMFH publishing team

Keystone Bacteroides strain restitution
leads to microbiome recovery and reduced risk
of colitis in genetically susceptible mice

New findings in mice have found a keystone Bacteroides
strain that reduces colitis risk when engrafted during early
life in a gut microbiome disrupted by antibiotics.

The gut microbiome in personalized
nutrition and medicine: takeaways
from the 2022 GMFH Summit

This post highlights the major learnings from the conference and
how they might impact clinical practice in the foreseeable future.

Probiotics with an anti-inflammatory effect may
reduce abdominal pain and hours of hospitalization
in adult patients with acute uncomplicated diverticulitis

This article explores what we know so far about the role of the gut microbiota
in diverticulitis and discusses two recent clinical trials on the role of probiotics
in managing acute uncomplicated diverticulitis.

The brain-gut-microbiota axis involves
different routes of communication and
can be targeted to influence brain and behavior

The gut-brain connection is largely shaped by the composition and function
of gut-dwelling microbial communities. This review article addresses how the
brain and gut communicate and considers potential psychobiotic therapies.

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