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2022 CeZAP Infectious Diseases Symposium
October 7, 2022
8:30 am - 5:30 pm
The Inn at Virginia Tech
Keynote speakers include:
Jennifer McQuiston
Deputy Director, Division of High Consequence Pathogens and Pathology
Centers for Disease Control and Prevention
T. Jake Liang
NIH Distinguished Investigator and Member of National Academy of Medicine, NIH
Sue VandeWoude
Director of One Health Institute and Member of National Academy of Sciences, Colorado State University
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Congratulations to the following CeZAP Affiliated Faculty Members on receiving the following promotions:
Promotion to associate professor with tenure
- Lauren Childs, mathematics
- Rebecca Hester, science, technology, and society
Promotion to professor
- Zhaomin Yang, biological sciences
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Leigh-Anne Krometis was recenlty awarded The Universities Council on Water Resources (UCOWR)
Mid Career award for Applied Water Research
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Recent Publications by CeZAP Affiliated Faculty
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EGR1 Upregulation during Encephalitic Viral Infections Contributes to Inflammation and Cell Death Lehman C, Smith A, Kelly J, Jacobs JL, Dinman JD, Kehn-Hall K. Viruses DOI: 10.3390/v14061210
Genome size distributions in bacteria and archaea are strongly linked to evolutionary history at broad phylogenetic scales Martinez-Gutierrez CA, Aylward FO. PLoS Genet DOI: 10.1371/journal.pgen.1010220
Sarcoptic mange: An emerging panzootic in wildlife Escobar LE, Carver S, Cross PC, Rossi L, Almberg ES, Yabsley MJ, Niedringhaus KD, Van Wick P, Dominguez-Villegas E, Gakuya F, Xie Y, Angelone S, Gortázar C, Astorga F. Transbound Emerg Dis
DOI: 10.1111/tbed.14082
Relating Eulerian and Lagrangian spatial models for vector-host disease dynamics through a fundamental matrix Bernal E, Saucedo O, Tien J. J Math Biol
DOI: 10.1007/s00285-022-01761-z
Integrating Environmental Dimensions of "One Health" to Combat Antimicrobial Resistance: Essential Research Needs. Jin L, Pruden A, Boehm AB, Alvarez PJJ, Raskin L, Kohn T, Li X. Environ Sci Technol DOI: 10.1021/acs.est.2c01651
Investigating plant disease outbreaks with long-read metagenomics: sensitive detection and highly resolved phylogenetic reconstruction applied to Xylella fastidiosa. Johnson MA, Liu H, Bush E, Sharma P, Yang S, Mazloom R, Heath LS, Nita M, Li S, Vinatzer BA .Microb Genom
DOI: 10.1099/mgen.0.000822
Stress Hormones Epinephrine and Corticosterone Selectively Reactivate HSV-1 and HSV-2 in Sympathetic and Sensory Neurons Goswami P, Ives AM, Abbott ARN, Bertke AS. Viruses
DOI: 10.3390/v14051115
Behavioral and postural analyses establish sleep-like states for mosquitoes that can impact host landing and blood feeding. Ajayi OM, Marlman JM, Gleitz LA, Smith ES, Piller BD, Krupa JA, Vinauger C, Benoit JB. J Exp Bio DOI: 10.1242/jeb.244032
Species-Specificity in Thermopreference and CO2-Gated Heat-Seeking in Culex Mosquitoes Reinhold JM, Chandrasegaran K, Oker H, Crespo JE, Vinauger C, Lahondère C. Insects DOI: 10.3390/insects13010092
Thermal biology of invasive Aedes mosquitoes in the context of climate change. Lahondère C, Bonizzoni M. Curr Opin Insect Sci DOI: 10.1016/j.cois.2022.100920
Particle-mediated Histotripsy for the Targeted Treatment of Catheter-based Medical Device Biofilms Childers C, Edsall C, Mehochko I, Mustafa W, Durmaz Y, Klibanov A, Rao J, Vlaisavljevich E. BME Frontiers
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Antibiotic perturbation of gut bacteria does not significantly alter host responses to ocular disease in a songbird species
Weitzman CL, Belden LK, May M, Langager MM, Dalloul RA, Hawley DM. PeerJ
DOI: 10.7717/peerj.13559
Hepatitis E virus infects brain microvascular endothelial cells, crosses the blood-brain barrier, and invades the central nervious system Tian D, Li W, Heffron CL, Wang B, Mahsoub HM, Sooryanarain H, Hassebroek AM, Clark-Deener S, LeRoith T, Meng XJ Proc Natl Acad Sci U S A DOI: 10.1073/pnas.2201862119
Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors.
Fritzemeier R, Foster D, Peralta A, Payette M, Kharel Y, Huang T, Lynch KR, Santos WL. J Med Chem DOI: 10.1021/acs.jmedchem.1c02171
Ligand-free copper-catalyzed borylative defluorination: access to gem-difluoroallyl boronic acid derivatives. Gates AM, Jos S, Santos WL. Org Biomol Chem DOI: 10.1039/d1ob01533h
Long-read metagenomic sequencing reveals shifts in associations of antibiotic resistance genes with mobile genetic elements from sewage to activated sludge. Dai D, Brown C, Bürgmann H, Larsson DGJ, Nambi I, Zhang T, Flach CF, Pruden A, Vikesland PJ. Microbiome
DOI: 10.1186/s40168-021-01216-5
Occurrence of opportunistic pathogens in private wells after major flooding events: A four state molecular survey. Mapili K, Rhoads WJ, Coughter M, Pieper KJ, Edwards MA, Pruden A. Sci Total Environ
DOI: 10.1016/j.scitotenv.2022.153901
Establishment of a gnotobiotic pig model of Clostridioides difficile infection and disease Nyblade C, Parreno V, Zhou P, Hensley C, Oakes V, Mahsoub HM, Kiley K, Frazier M, Frazier A, Zhang Y, Feng H, Yuan L. Gut Pathog DOI: 10.1186/s13099-022-00496-y
Successful restoration of archived ovine formalin fixed paraffin-embedded tissue DNA and single nucleotide polymorphism analysis. Kravitz A, Tyler R, Manohar BM, Ronald BSM, Collins MT, Sriranganathan N. Vet Res Commun DOI: 10.1007/s11259-022-09937-0
A Reduced F420-Dependent Nitrite Reductase in an Anaerobic Methanotrophic Archaeon Heryakusuma C, Susanti D, Yu H, Li Z, Purwantini E, Hettich RL, Orphan VJ, Mukhopadhyay B. J Bacteriol
DOI: 10.1128/jb.00078-22
Simulations of cross-amyloid aggregation of amyloid-β and islet amyloid polypeptide fragments Kawecki GE, King KM, Cramer NA, Bevan DR, Brown AM. Biophys J
DOI: 10.1016/j.bpj.2022.05.007
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Help us advertise the ID IGEP program and recruit students.
Please consider showing this slide at the end of any upcoming conference presentations and /or in any undergraduate classes you are teaching.
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COVID-19 Outreach Activities by CeZAP Affiliated Faculty Linsey Marr
COVID-19 Publications by CeZAP Affiliated Faculty
Vaccine Effectiveness during Outbreak of COVID-19 Alpha (B.1.1.7) Variant in Men’s Correctional Facility, United States. Silverman RA, Ceci A, Cohen A, Helmick M, Short E, Bordwine P, Friedlander MJ, and Finkielstein CV. Emerg Infect Dis. DOI: 10.3201/eid2807.220091
Modeling waning and boosting of COVID-19 in Canada with vaccination Childs LM, Dick DW, Feng Z, Heffernan J, Li J, Rost G. Epidemics DOI: 10.1016/j.epidem.2022.100583
Filtration evaluation of expired elastomeric P-100 filter cartridges after months of real-world use during the coronavirus disease 2019 (COVID-19) pandemic.
Baffoe-Bonnie AW, Zhang KS, Pan J, Simpkins K, Marr LC. Infect Control Hosp Epidemiol. DOI: 10.1017/ice.2021.104
Effect of Surface Porosity on SARS-CoV-2 Fomite Infectivity. Hosseini M, Poon LLM, Chin AWH, Ducker WA. ACS Omega DOI: 10.1021/acsomega.1c06880
Untangling the changing impact of non-pharmaceutical interventions and vaccination on European COVID-19 trajectories. Ge Y, Zhang WB, Wu X, Ruktanonchai CW, Liu H, Wang J, Song Y, Liu M, Yan W, Yang J, Cleary E, Qader SH, Atuhaire F, Ruktanonchai NW, Tatem AJ, Lai S. Nat Commun DOI: 10.1038/s41467-022-30897-1
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Recent Research Grants Awarded to CeZAP Affiliated Faculty
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- “Development and characterization of a sublethal-sequelae mouse model of EEEV infection”
- PI Kylene Kehn-Hall, Co-PI: Michelle Theus (Virginia Tech) and Barney Bishop (George Mason University)
- TOTAL AWARD: $2,171,347 (DIRECT: $1,599,400; INDIRECT: $571,947)
The major goals of this project are 1) Determine the cognitive impact of EEEV infection. 2) Identify circulating correlates of neuropathology. 3) Determine the host responses that contribute to EEEV-induced cognitive defects, and 4) Perform proof-of-concept therapeutic testing in the EEEV neurological sequelae model.
- NIH National Cancer Institute, National Institutes of Health"Deploying Histropsy Based Tumor Ablation Strategies to Treat Pancreatic Cancer"
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Outreach activities by CeZAP affiliated faculty
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Lijuan Yuan recently gave an invited seminar at the US Association for Gnotobiotics. "Perfecting the gnotobiotic pig model system for the study of human enteric viruses and vaccines"
The following CeZAP affiliated faculty were recently featured on Podcasts:
The People's Pharmacy The Peoples Perspecitve on Medicine
Show 1227: What Do You Need to Know About Airborne Viruses?
- Linsey Marr discusses how ventilation is crucial when it comes to preventing the spread of airborne viruses. Why is nobody listening? Learn how to protect yourself! LINK TO PODCAST>>
Ticktective: A Straight-Forward Explanation of the Complications With Lyme Diagnostics and a Potential New Direct Detection Test
- Brandon Jutras explains why there are no accurate tests for Lyme disease available and how his research is looking to change that LINK TO PODCAST>>
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To Foster and Promote a Cohesive and Synergistic Environment for Interdisciplinary and Collaborative Research
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