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FUNDamentals — Office of Research Development
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UNC's Office of Research Development's FUNDamentals provides researchers with updates related to extramural funding, on-campus research development and other timely information in support of Carolina’s research enterprise.

Contents:

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Save the date: University Research Week October 10-14, 2022

During the week of October 10 - 14, 2022, University Research Week events will highlight the impact of research on the state of North Carolina and the exceptional achievements of Carolina researchers across many disciplines as they strive to answer: What's Next? The celebration will also honor the scientific discovery and scholarly creativity of today and our institution's 229-year history during University Day on October 12.

University Research Week is an annual, campus-wide event sponsored by the Office of the Vice Chancellor for Research and the Office of Undergraduate Research.

The form for submitting events to host during the celebration is now available. If you have any questions regarding University Research Week, or are interested in hosting an event during the celebration, contact OVCR Director of Communications Layla Dowdy or Interim Director of the Office of Undergraduate Research Bob Pleasants.

Special Funding Opportunities

 

 

North Carolina Biotechnology Center Innovation Impact Grant (IIG) & Flash Grants

The NCBC Flash Grant program identifies and energizes creative ideas that exhibit early indications of exceptional commercial potential. Flash Grants support short, tightly-focused research projects in these two categories:

  • To obtain initial exploratory, proof-of-concept, or feasibility data necessary to suggest the disruptive potential of a life sciences technology
  • To conduct the final experiment(s) needed to advance a basic life sciences research program into the translational research phase of development

The FY23 Flash Grant Cycle 1 solicitation is open to sustainability-focused projects in any life sciences sector as described below, except Class I medical devices and consumer products:

  • Sustainable agricultural research and development methods, products, and technologies (Sustainable/Regenerative AgTech)
  • Sustainable laboratory research practices, technologies, and products
  • Sustainable scaling/manufacturing of life sciences products and technologies
  • Environmental sustainability

Deadline September 14, 2022

The Innovation Impact Grant (IIG) program supports the purchase of shared use research equipment for core facilities at academic or nonprofit institutions that foster innovation within North Carolina’s life sciences ecosystem.

Priority will be given to proposals demonstrating a high impact on the applicant institution and broader life sciences research community.

Up to $150,000 may be requested; a cash match is required. Please see the application guidelines for details.

Funds are available to any North Carolina university or non-profit research institute.

IIG FAQs are viewable here: www.ncbiotech.org/grant-faq.

Deadline: Wednesday, October 12, 2022 (noon)

___________________________________________________________________
 

New funding opportunity in Clinical and Translational Science

NC TraCS is seeking proposals that focus on understanding a scientific or operational principle underlying a step of the translational research process with the goal of developing generalizable principles to accelerate translation.

The new CTS Pilot Program will support investigation focused on developing, demonstrating, and disseminating scientific and operational innovations that improve the efficiency and effectiveness of clinical translation from: identification, to first-in-human studies, to medical practice implementation, to community health dissemination—so that advances can be applied to research on any target or disease.

Short concept proposals are due October 11. More information & RFA: https://tracs.unc.edu/services/pilot-program/cts
 

___________________________________________________________________

Funding Info Session: NEW Clinical & Translational Science Pilot RFA

NC TraCS has released a new pilot RFA that is focused on translational science. Since this is a departure from our long-standing pilot RFAs focused on translational research, we are holding two information sessions for investigators interested in learning more about this new funding opportunity. Participate in the session that works best for your schedule.

September 20, 2 - 3 p.m. | REGISTER https://go.unc.edu/CTS920info

September 29, 10 - 11 a.m. | REGISTER https://go.unc.edu/CTS929info

___________________________________________________________________
 

Call for pilot award applications focused on health equity and clinical research in Southeastern NC

The Research Advisory Council, a joint committee composed of research leaders from Novant Health, NH-New Hanover Regional Medical Center, UNC Health, and UNC School of Medicine, is accepting applications for two pilot award programs that will result in awards of up to $50,000. Applications are due Oct 4.

Promoting Health Equity in Southeastern NC award program seeks to support research projects that broadly address strategies for reducing barriers and promoting optimal outcomes for historically marginalized populations through a lens of access, value, and equity. Specifically, projects should promote research to understand and improve health equity challenges relevant to the community in Southeastern North Carolina.

Promoting Clinical Research in Southeastern NC award program seeks to support clinical research focused on relevant community health challenges such as cancer, heart disease, stroke, diabetes, primary care, COVID-19, women and children’s health, substance use disorder and more. Cancer investigators are particularly encouraged to develop collaborative projects in response to this opportunity.

More information & RFAs: https://tracs.unc.edu/index.php/services/pilot-program/research-advisory-council-awards

___________________________________________________________________

The UNC NORC will award two grants of $40,000 in direct costs.

Projects may be biomedical, epidemiological, or clinical. They may include laboratory or non-laboratory research projects that focus either on human nutrition, animal work that could be translated to human nutrition, or basic research related to nutrition or obesity. Human nutrition or human obesity projects may focus on inpatient or outpatient studies or on epidemiological or community-based research that is social or behavioral in nature.
To support their projects, investigators are strongly encouraged to use one or more of the services offered by the four UNC NORC cores. We welcome applications intended to generate pilot data that will address reviewers’ comments from recently scored grants.

Pilot Award Eligibility

Faculty members and senior postdoctoral scholars at the University of North Carolina at Chapel Hill who fall into one of the following three categories are eligible to apply:
  1. Applicants must be new investigators without current or past NIH research support (R01, P01 or R24) as a PD/PI. Current or past K01 awards are acceptable. OR
  2. Applicants must be established, funded investigators with no previous work in nutritional sciences and/or obesity and who wish to test the applicability of their expertise to a nutritional science and/or obesity-related problem. OR
  3. Applicants must be established investigators in nutrition/obesity research who propose testing innovative ideas that represent a clear departure from their ongoing research interests.

Deadline: October 31, 2022

The newly revised guidelines for proposals can be found here. Complete applications must be submitted as a single PDF file by 5:00 PM ET on Monday, October 31, 2022, using the online form here. For more information about the application process, please contact Dr. John Easterbrook.
 

NC Policy Collaboratory Opioid Abatement and Recovery Research Program 2022

The primary goal of this RFP is to generate practical end products that can be used by local governments and/or the communities they serve to address the consequences of the opioid crisis. Applications are sought in two priority areas:

  1. Research and surveillance for treatment recovery, harm reduction and other opioid abatement strategies.
  2. Supporting local government spending on opioid abatement efforts.

More information about each priority area is provided in the full application instructions.

Due to the impact of the opioid crisis on communities across the State, this RFP may prioritize proposals that demonstrate effective community and/or local government engagement, particularly involving or serving underrepresented or underserved groups, with scopes and study designs that are acceptable to and directly benefit these partners. Proposers may request up to $380,000 in direct costs.

Complete application information may be found at the Collaboratory RFP Page
Deadline: October 28, 2022

CURRENT LIMITED SUBMISSION & AWARD OPPORTUNITIES

Current, up-to-date information on UNC's Limited Submissions & Award Opportunities can be found at the Limited Submissions and Awards Portal (LAMSeS)

Any limited submission that is not located within LAMSeS and has less than 45-days before the first due date will be approved to submit on a first-come, first-serve basis. Please contact limited_submission@unc.edu to verify.

Limited Submission Renewal Policy

Priority is granted to teams seeking to renew a proposal for a limited submission. Please contact limited_submission@unc.edu to confirm renewal.

Supporting UNC Faculty through Honors and Recognition


Visit our webpage for nomination deadlines! Supporting UNC Faculty: Honorific Societies and Federal Advisory Committees

The Alan T. Waterman Award

The Alan T. Waterman is the U.S. National Science Foundation’s (NSF) Highest Honor. The award recognizes an outstanding early career researcher in any field of science or engineering supported by the NSF. In addition to a medal, the awardee receives a grant of $1,000,000 to use over a five-year period for scientific research or advanced study in the mathematical, physical, biological, engineering, social, or other sciences at the institution of the recipient's choice. Congress established the award in August 1975 to mark NSF's 25th anniversary and honor the agency's first director.

NSF is seeking nominations for exceptional candidates that represent the diversity of the U.S. Nominations for the 2023 Alan T Waterman Award will be accepted from July 18 to September 16, 2022.

Eligibility and selection criteria

  • Nominees must:
    • Be U.S. citizens or permanent residents.
    • Be 40 years of age or younger OR not be more than 10 years beyond receipt of their Ph.D. by December 31st of the year they are nominated.
  • Nominees should have demonstrated exceptional individual achievements in scientific or engineering research of sufficient quality, originality, innovation and significant impact on the field to place them at the forefront of their peers.

Please visit www.nsf.gov/Waterman for information on nominations requirements and to access the nomination portal.
 

Call for Committee Member Nominations for NASEM Toward Sequencing and Mapping RNA Modifications Study

The National Academies of Sciences, Engineering, and Medicine is initiating a consensus study that seeks to understand what is needed to enhance the scientific community’s ability to detect known and unknown RNA modifications more effectively. The study committee will examine the scientific needs and current technologies for sequencing RNA modifications; current databases storing information about RNA modifications; scientific and technological hurdles in direct sequencing of RNA modifications; and identification of computational and analytic technologies, data ecosystem, policy, workforce, and infrastructure needs to support sequencing and analysis of RNA modifications.

The study will be carried out by a committee of approximately 10-12 volunteer experts in the fields of RNA biology, computational biology, molecular biology and related -omics data and technologies, sequencing technologies, biotechnology, life science policy, and bioethics. In addition, experts knowledgeable in workforce development and infrastructure needs to support large sequencing efforts will be included on the committee. These experts may be from industry, academia, nonprofit research organizations, and government laboratories.

For more information about this study, including the committee's Statement of Task, please visit the project website.
If you wish to use Twitter, you can find a click-to-tweet link here: https://ctt.ac/3I421

Please submit all nominations (for yourself and others) through the online nomination form by September 9, 2022, which includes a more detailed description of the study.”
 

2023 Canada Gairdner Awards

The Gairdner Foundation has invited the University of North Carolina at Chapel Hill to nominate outstanding biomedical or global health scientists for the 2023 Canada Gairdner Awards. Gairdner Awardees have represented the leading scientific minds in biomedicine for over 60 years. The Gairdner Foundation is dedicated to recognizing the most impactful work on human health, and to sharing it with the world. This opportunity does not limit the number of nominations per institution and is open to any eligible member of faculty. Two award categories for the $100,000 CAD prize are open to international submissions:

  • The Canada Gairdner International Award is given for transformative biomedical discovery research and is considered one of the foremost early indicators of Nobel Prize recipients
  • The Canada Gairdner Global Health Award has become the leading recognition of excellence in global health and health equity research.

Nominations for the 2023 awards are due by 11:59 pm PDT on October 1, 2022. Nominations of candidates representing under-represented communities in scientific awards and in the research community at large are strongly encouraged. All details on the awards and nomination process are available at gairdner.org

Early Notice - NIH Concept Clearances

NIH Concept Clearances
NIH Institute Councils meet three times a year - around Feb/May/Sep. The public-access portion of these council meetings includes the presentation of funding concepts for discussion and approval. Thus, concept clearances are often the earliest notice of NIH interest in a new topic format.

Council of Councils | 9/8 | Concepts on the agenda include: 
- ORIP Concept Clearance: Reissue of Resource-Related Research Projects for Development of Animal Models and Related Materials
- Informational Concept Update: National Institute of Food and Agriculture/USDA and NIH:   Dual Purpose with Dual Benefit Research in Biomedicine and Agriculture Using Agriculturally Important Large Domestic Animal Species (R01)
- New ORIP Concept Clearance: Somatic Cell Genome Editing Testing Center
- New Common Fund (CF) Concept Clearance: Human Virome Program
- New CF Concept Clearance: Advancing Health Communication Science and Practice
- New OBSSR Concept Clearance: Accelerating Behavioral and Social Science Through Ontology Development and Use
- CF Concept Clearance: Common Fund Data Ecosystem Phase 2
- CF Concept Clearance: Reissue of Molecular Transducers of Physical Activity (MoTrPAC) RFAs
- New All of Us Concept Clearance: R03/R21 to Stimulate Novel Analyses Using All of Us Research Program Data
- New ONR Concept Clearance: Food as Medicine Networks or Centers of Excellence

NCI | 8/31 | No concept clearances on the agenda

NEI | 10/14 | Agenda not yet available

NHLBI | 9/13 | No concept clearances on the agenda

NHGRI | 9/20 | Agenda not yet available

NIA | 9/8 | Concept clearance discussion is an agenda item but no concepts are listed

NIAAA | 9/8 | Topics that might be concept clearances are on the agenda but are ambiguous - they could be reports. 

NIAID | 9/12 | Concepts are listed on sub-committee agendas

AIDS Research Advisory Committee agenda
- Opportunities for HIV Cure Strategies at the Time of ART Initiation
- Pulmonary Outcomes and Sequelae after Treatment - TB (POST-TB)
- Synthetic Nucleic Acid Platforms for HIV-1 (SNAP-H)
- Rational Systematic Characterization and Selection of Adjuvants for HIV Vaccine Candidates (R-CASA)
- Innovation for HIV Vaccine Discovery (IHVD)
- Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD)
- NIH Medical Scientist Partnership Program

Allergy, Immunology, and Transplantation Subcommittee agenda
- Consortium for Food Allergy Research, Clinical Research Units (U01, Clinical Trial Optional)
- Consortium for Food Allergy Research, Clinical Research, CoFAR Leadership Center (UM1, Clinical Trial Required)
- Vaccine Adjuvant Discovery Program
- Development of Radiation/Nuclear Medical Countermeasures (MCM) and Biodosimetry Devices
- Sex Differences in Radiation/Nuclear Research Models: Underlying Pathways, Biomarkers of Inquiry, and Medical Countermeasures Responses (U01, Clinical Trial Not Allowed)

Microbiology and Infectious Diseases Subcommittee Agenda
- Sexually Transmitted Infections (STI) Cooperative Research Centers (CRC): Vaccine Development
- Advancing Development of Diagnostics for Congenital and Acquired Syphilis
- Preclinical Models of Infectious Diseases
- Genomic Centers for Infectious Diseases
- Therapeutics for Eliminating Hepatitis B Virus cccDNA
- Development of Medical Countermeasures for NIAID Priority Biodefense and Emerging Infectious Diseases
- Resources and Workforce Development for the Regional Biocontainment Laboratories

NIAMS | 9/14 | Agenda not yet available

NIBIB | 9/13 | Agenda not yet available

NICHD | 9/12 | Concepts on the agenda include: 
- Using Archived Data and Specimen Collections to Advance Maternal and Pediatric HIV-AIDS Research
- Development of Novel Nonsteroidal Contraceptive Methods 
- Centers for Research on Health Disparities in Uterine Fibroids
- Advancing Opportunities for Limb Regeneration Research
- Pediatric Critical Care and Trauma Scientist Development Program
- Translational Research in Pediatric and Obstetric Pharmacology
- NICHD High Priority Research Areas
- INCLUDE Project Initiatives

NIDCD | 9/8 | No concept clearances on the agenda

NIDCR | 9/13 | Concepts on the agenda include:
- Collaborative Science to Achieve Disruptive Innovations in Dental, Oral, and Craniofacial (DOC) Research
- Maternal Health and Dental, Oral and Craniofacial Health and Development of Their Offspring
- Understanding Persistent Oral Human Papillomavirus and Human Immunodeficiency Virus Co-infection and Its Role with Oropharyngeal Cancer Induction
- Chronic Inflammation of the Oral Cavity An Agent for Oral Mucosal Disease
- Developing Salivary Components as Therapeutics for Oral Health
- Apply Data Science in Translational Dental, Oral, and Craniofacial Research

NIDDK | 9/7 | Concept clearance discussion is an agenda item but no concepts are listed

NIDA | 9/13 | Concepts on the agenda include: 

- Patient Engagement Resource Centers
- Leveraging Inpatient Medical or Surgical Hospitalizations to Improve Outcomes for People Who Use Drugs
- Rapid Translation of Epidemiological Findings into Interventions to Prevent Substance Use and Addiction
- Rural Community-Centered Prevention and Harm Reduction Research: Responding to the Fourth Wave Opioid/Psychostimulant Epidemic and its HIV/HCV Consequences in the U.S. 
- Using Cost‐Effective Technology to Develop Accessible and Affordable Products to Reduce (or even eliminate) Disparities in Substance Use Disorder (SUD) Diagnosis and Treatment 
- Marijuana Farm and Analytics to Produce Consistent, High Quality Material to Facilitate Cannabis Research 
- Exploratory Clinical Neuroscience Research on Substance Use Disorders 
- Responsible Analyses of Complex, Large‐Scale Data
- Translating Socioenvironmental Influences on Neurocognitive Development and Addiction Risk (TransSINDA) 
- Mechanistic Research on Neuromodulation for SUD Treatment
- Advancing Psychedelics Research for Treating Addiction 
- Remote Assessment 1: Identifying and Addressing Barriers to Participant Engagement 
- Remote Assessment 2: Validation and Expansion of Remote Assessments of SUD-Relevant Behaviors
- NIDA International Program 

NIEHS | 9/13 | Concepts on the agenda include:
- Data and Metadata Standards Efforts to Promote Development and Adoption of a Harmonized Environmental Health Language
- Superfund Hazardous Substance Research and Training Program

NIGMS | 9/15 | Concepts on the agenda include:
- Limited Competition: Centers of Biomedical Research Excellence (COBRE) Phase 3 - Transitional Centers
- Modules for Enhancing Biomedical Research Workforce Training
- Maximizing Investigators Research Award (MIRA) for Early Stage Investigators
- Coordination Center for the Models of Infectious Disease Agent Study (MIDAS) Program
- Research Evaluation and Commercialization Hubs (REACH)
- IDeA Clinical and Translational Research Networks (CTRN)
- IDeA Clinical and Translational Research Development Awards (CTRD)
- Tribal IRB Development Grants
- Tribal IRB Grants​
- Diversity Enhancing National Research Service Award Institutional Training Programs for Tribal Organizations
- National Centers for Cryoelectron Microscopy (Cryo-EM)

NIMHD | 9/2 | Concepts on the agenda include:
- Latin America: Synergizing Health Research Across the Hemisphere
- Health Disparities Experienced Among Persons Living with Disabilities

NINDS | 9/7 | Concept clearance discussion is an agenda item but no concepts are listed

NINR | 9/13 |  No concept clearances on the agenda

NLM | 9/13 | Agenda not yet available

NCATS | 9/22 | Agenda not yet available

NCCIH | 9/9 | No concept clearances on the agenda

Early Notice - NSF Dear Colleague Letters

NSF Dear Colleague Letters
Dear Colleague Letters (DCLs) are released as needed by the National Science Foundation (NSF) to inform the NSF research community of relevant requests for information, upcoming opportunities, and policy changes.

August 16-  September 6, 2022, NSF released the following DCL:

  • 8/16 | Supplements for Access to Semiconductor Fabrication (ASF) | nsf22113
  • 8/18 | Provisioning Advanced Cyberinfrastructure to Further Research on the Monkeypox Virus | nsf22115
  • 8/29 | Research Coordination Networks for Semiconductors (RCN-SC) | nsf22116

CDMRP Current Funding

The Department of Defense - Congressionally Directed Medical Research Programs (CDMRP) releases periodic funding opportunities of interest to the UNC research community. In general, CDMRP programs require a Pre-Application after which, successful applicants are invited to submit a full application.

Open Funding Opportunities (link to a synopsis of open opportunities).

Breast Cancer 

  • Breakthrough Award Levels 1 & 2 | LOI due 9/22/22
  • Era of Hope Scholar Award | LOI due 9/22/22
Kidney Cancer Research Program
  • Academy of Kidney Cancer Investigators – Early-Career Scholar Award | LOI due 9/29/22
  • Nurse-Initiated Research Award | LOI due 9/29/22
  • Clinical Trial Award | LOI due 9/29/22
Melanoma Research Program 
  • Melanoma Academy Scholar Award | LOI due 9/14/22
  • Mid-Career Accelerator Award | LOI due 9/14/22
  • Team Science Award | LOI due 9/14/22
  • Focused Program Award – Rare Melanoma | LOI due 9/14/22
Peer Reviewed Cancer Research Program
  • Behavioral Health Science Award (BHSA) | LOI due 9/28/22
  • Career Development Award (CDA) – Scholar Option | LOI due 9/28/22
Reconstructive Transplant Research Program
  • Concept Award | Preproposal due 9/28/22

Solicitations for Federal Advisory Committee Nominations

 
UNC’s Offices of Federal Affairs and Research Development identify federal advisory committee openings and support faculty by submitting nomination materials on their behalf. Please email Roxana Boyd, Assistant Director of Federal Affairs (roxanaboyd@unc.edu) if you are interested in being nominated for any of the opportunities or would like to recommend a colleague for nomination.
 
           

News you can use

Lab creates wireless, wearable sensor for deep-tissue monitoring

By Shellie Edge, Applied Physical Sciences

A team led by Wubin Bai developed a novel patch that provides a safe, real-time, less invasive and low-cost way to track a patient’s recovery.

Left: Schematic illustration showing a cross-sectional view of the skin-interfaced wireless sensing patch for muscular monitoring. Right: the envisioned intelligent health care enabled by the wearable sensing patch, that closely connects users with clinical professionals over cloud-based computational systems.

https://thewell.unc.edu/2022/08/31/lab-creates-wireless-wearable-sensor/

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