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| Comparison of Days Alive Out of Hospital With Initial Invasive vs Conservative Management: A Prespecified Analysis of the ISCHEMIA Trial. |
White HD, O'Brien SM, Alexander KP, Boden WE, Bangalore S, Li J, Manjunath CN, Lopez-Sendon JL, Peteiro J, Gosselin G, Berger JS, Maggioni AP, Reynolds HR, Hochman JS, Maron DJ.
JAMA Cardiol. 2021 Sep 1;6(9):1023-1031. doi: 10.1001/jamacardio.2021.1651. |
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| Regulatory variants in TCF7L2 are associated with thoracic aortic aneurysm. |
Roychowdhury T, Lu H, Hornsby WE, Crone B, Wang GT, Guo DC, Sendamarai AK, Devineni P, Lin M, Zhou W, Graham SE, Wolford BN, Surakka I, Wang Z, Chang L, Zhang J, Mathis M, Brummett CM, Melendez TL, Shea MJ, Kim KM, Deeb GM, Patel HJ, Eliason J, Eagle KA, Yang B, Ganesh SK, Brumpton B, Åsvold BO, Skogholt AH, Hveem K; VA Million Veteran Program, Pyarajan S, Klarin D, Tsao PS, Damrauer SM, Leal SM, Milewicz DM, Chen YE, Garcia-Barrio MT, Willer CJ.
Am J Hum Genet. 2021 Sep 2;108(9):1578-1589. doi: 10.1016/j.ajhg.2021.06.016. |
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| Trans-lesional fractional flow reserve gradient as derived from coronary CT improves patient management: ADVANCE registry. |
Takagi H, Leipsic JA, McNamara N, Martin I, Fairbairn TA, Akasaka T, Nørgaard BL, Berman DS, Chinnaiyan K, Hurwitz-Koweek LM, Pontone G, Kawasaki T, Rønnow Sand NP, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, Mullen S, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Douglas PS, Patel MR, Nieman K, Ihdayhid AR.
J Cardiovasc Comput Tomogr. 2021 Sep 2:S1934-5925(21)00418-4. doi: 10.1016/j.jcct.2021.08.003. |
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| Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis. |
Jiang Z, Zhao M, Voilquin L, Jung Y, Aikio MA, Sahai T, Dou FY, Roche AM, Carcamo-Orive I, Knowles JW, Wabitsch M, Appel EA, Maikawa CL, Camporez JP, Shulman GI, Tsai L, Rosen ED, Gardner CD, Spiegelman BM, Svensson KJ.
Cell Metab. 2021 Sep 7;33(9):1836-1852.e11. doi: 10.1016/j.cmet.2021.07.010. |
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| Worldwide differences in primary prevention implantable cardioverter defibrillator utilization and outcomes in hypertrophic cardiomyopathy. |
Nauffal V, Marstrand P, Han L, Parikh VN, Helms AS, Ingles J, Jacoby D, Lakdawala NK, Kapur S, Michels M, Owens AT, Ashley EA, Pereira AC, Rossano JW, Saberi S, Semsarian C, Ware JS, Wittekind SG, Day S, Olivotto I, Ho CY.
Eur Heart J. 2021 Sep 7:ehab598. doi: 10.1093/eurheartj/ehab598. |
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| Response by Shah et al to Letter Regarding Article, "Cell-Free DNA to Detect Heart Allograft Acute Rejection". |
Shah P, Agbor-Enoh S, Tunc I, Hsu S, Russell S, Feller E, Shah K, Rodrigo ME, Najjar SS, Kong H, Pirooznia M, Fideli U, Bikineyeva A, Marishta A, Bhatti K, Yang Y, Mutebi C, Yu K, Kyoo Jang M, Marboe C, Berry GJ, Valantine HA; GRAfT (Genomic Research Alliance for Transplantation) Investigators.
Circulation. 2021 Sep 7;144(10):e198-e199. doi: 10.1161/CIRCULATIONAHA.121.055697. |
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| Dynamic Myocardial Perfusion CT for the Detection of Hemodynamically Significant Coronary Artery Disease. |
Nous FMA, Geisler T, Kruk MBP, Alkadhi H, Kitagawa K, Vliegenthart R, Hell MM, Hausleiter J, Nguyen PK, Budde RPJ, Nikolaou K, Kepka C, Manka R, Sakuma H, Malik SB, Coenen A, Zijlstra F, Klotz E, van der Harst P, Artzner C, Dedic A, Pugliese F, Bamberg F, Nieman K.
JACC Cardiovasc Imaging. 2021 Sep 8:S1936-878X(21)00621-5. doi: 10.1016/j.jcmg.2021.07.021. |
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| World regional differences in outcomes for patients with peripheral artery disease: Insights from the EUCLID trial. |
Norgren L, North R, Baumgartner I, Berger JS, Blomster JI, Hiatt WR, Jones WS, Katona BG, Mahaffey KW, Mulder H, Patel MR, Rockhold FW, Fowkes FGR.
Vasc Med. 2021 Sep 13:1358863X211038620. doi: 10.1177/1358863X211038620. |
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| Association Among Local Hemodynamic Parameters Derived From CT Angiography and Their Comparable Implications in Development of Acute Coronary Syndrome. |
Yang S, Choi G, Zhang J, Lee JM, Hwang D, Doh JH, Nam CW, Shin ES, Cho YS, Choi SY, Chun EJ, Nørgaard BL, Nieman K, Otake H, Penicka M, Bruyne B, Kubo T, Akasaka T, Taylor CA, Koo BK.
Front Cardiovasc Med. 2021 Sep 13;8:713835. doi: 10.3389/fcvm.2021.713835. |
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| Effects of initial invasive vs. initial conservative treatment strategies on recurrent and total cardiovascular events in the ISCHEMIA trial. |
Lopez-Sendon JL, Cyr DD, Mark DB, Bangalore S, Huang Z, White HD, Alexander KP, Li J, Nair RG, Demkow M, Peteiro J, Wander GS, Demchenko EA, Gamma R, Gadkari M, Poh KK, Nageh T, Stone PH, Keltai M, Sidhu M, Newman JD, Boden WE, Reynolds HR, Chaitman BR, Hochman JS, Maron DJ, O'Brien SM.
Eur Heart J. 2021 Sep 13:ehab509. doi: 10.1093/eurheartj/ehab509. |
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| Increased tissue stiffness triggers contractile dysfunction and telomere shortening in dystrophic cardiomyocytes. |
Chang ACY, Pardon G, Chang ACH, Wu H, Ong SG, Eguchi A, Ancel S, Holbrook C, Ramunas J, Ribeiro AJS, LaGory EL, Wang H, Koleckar K, Giaccia A, Mack DL, Childers MK, Denning C, Day JW, Wu JC, Pruitt BL, Blau HM.
Stem Cell Reports. 2021 Sep 14;16(9):2169-2181. doi: 10.1016/j.stemcr.2021.04.018. |
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| High-Intensity Statins Benefit High-Risk Patients: Why and How to Do Better. |
Grundy SM, Stone NJ, Blumenthal RS, Braun LT, Heidenreich PA, Lloyd-Jones D, Orringer CE, Saseen JJ, Smith SC Jr, Sperling LS, Virani SS.
Mayo Clin Proc. 2021 Sep 14:S0025-6196(21)00434-1. doi: 10.1016/j.mayocp.2021.02.032. |
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| Outcomes of Participants with Diabetes in the ISCHEMIA Trials. |
Newman JD, Anthopolos R, Mancini GBJ, Bangalore S, Reynolds HR, Kunichoff DF, Senior R, Peteiro J, Bhargava B, Garg P, Escobedo J, Doerr R, Mazurek T, Gonzalez-Juanatey J, Gajos G, Briguori C, Cheng H, Vertes A, Mahajan S, Guzman LA, Keltai M, Maggioni AP, Stone GW, Berger JS, Rosenberg YD, Boden WE, Chaitman BR, Fleg JL, Hochman JS, Maron DJ.
Circulation. 2021 Sep 15. doi: 10.1161/CIRCULATIONAHA.121.054439. |
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| peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. |
Mulorz J, Shayan M, Hu C, Alcazar C, Chan AHP, Briggs M, Wen Y, Walvekar AP, Ramasubramanian AK, Spin JM, Chen B, Tsao PS, Huang NF.
Biomater Sci. 2021 Sep 15. doi: 10.1039/d1bm00685a. |
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| Association of Myocardial Blood Flow Reserve With Adverse Left Ventricular Remodeling in Patients With Aortic Stenosis: The Microvascular Disease in Aortic Stenosis (MIDAS) Study. |
Zhou W, Sun YP, Divakaran S, Bajaj NS, Gupta A, Chandra A, Morgan V, Barrett L, Martell L, Bibbo CF, Hainer J, Lewis EF, Taqueti VR, Dorbala S, Blankstein R, Slomka P, Shah PB, Kaneko T, Adler DS, O'Gara P, Di Carli MF.
JAMA Cardiol. 2021 Sep 15. doi: 10.1001/jamacardio.2021.3396. |
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| An integrated approach to identify environmental modulators of genetic risk factors for complex traits. |
Balliu B, Carcamo-Orive I, Gloudemans MJ, Nachun DC, Durrant MG, Gazal S, Park CY, Knowles DA, Wabitsch M, Quertermous T, Knowles JW, Montgomery SB.
Am J Hum Genet. 2021 Sep 22:S0002-9297(21)00335-9. doi: 10.1016/j.ajhg.2021.08.014. |
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| A Missense Variant in the IL-6 Receptor and Protection from Peripheral Artery Disease. |
Levin MG, Klarin D, Georgakis MK, Lynch J, Liao KP, Voight BF, O'Donnell CJ, Chang KM, Assimes TL, Tsao PS, Damrauer SM.
Circ Res. 2021 Sep 22. doi: 10.1161/CIRCRESAHA.121.319589. |
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| Valsartan in early-stage hypertrophic cardiomyopathy: a randomized phase 2 trial. |
Ho CY, Day SM, Axelsson A, Russell MW, Zahka K, Lever HM, Pereira AC, Colan SD, Margossian R, Murphy AM, Canter C, Bach RG, Wheeler MT, Rossano JW, Owens AT, Bundgaard H, Benson L, Mestroni L, Taylor MRG, Patel AR, Wilmot I, Thrush P, Vargas JD, Soslow JH, Becker JR, Seidman CE, Lakdawala NK, Cirino AL; VANISH Investigators, Burns KM, McMurray JJV, MacRae CA, Solomon SD, Orav EJ, Braunwald E.
Nat Med. 2021 Sep 23. doi: 10.1038/s41591-021-01505-4. |
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| Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death. |
Walsh R, Adler A, Amin AS, Abiusi E, Care M, Bikker H, Amenta S, Feilotter H, Nannenberg EA, Mazzarotto F, Trevisan V, Garcia J, Hershberger RE, Perez MV, Sturm AC, Ware JS, Zareba W, Novelli V, Wilde AAM, Gollob MH.
Eur Heart J. 2021 Sep 24:ehab687. doi: 10.1093/eurheartj/ehab687. |
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| Termination Based on Event Accrual in Per Protocol Versus Intention to Treat in the ROCKET AF Trial. |
Carnicelli AP, Hellkamp AS, Mahaffey KW, Singer DE, Breithardt G, Halperin JL, Hankey GJ, Piccini JP, Becker RC, Nessel CC, Berkowitz SD, Fox KAA, Califf RM, Patel MR.
J Am Heart Assoc. 2021 Sep 25:e022485. doi: 10.1161/JAHA.121.022485. |
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| Predictors of Outcome in the ISCHEMIA-CKD Trial: Anatomy versus Ischemia. |
Bainey KR, Fleg JL, Hochman JS, Kunichoff DF, Anthopolos R, Chernyavskiy AM, Demkow M, Lopez-Quijano JM, Escobedo J, Poh KK, Ramos RB, Lima EG, Schuchlenz H, Ali ZA, Stone GW, Maron DJ, O'Brien SM, Spertus JA, Bangalore S.
Am Heart J. 2021 Sep 25:S0002-8703(21)00237-4. doi: 10.1016/j.ahj.2021.09.008. |
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| Arrhythmias Other Than Atrial Fibrillation in Those With an Irregular Pulse Detected With a Smartwatch: Findings From the Apple Heart Study. |
Perino AC, Gummidipundi SE, Lee J, Hedlin H, Garcia A, Ferris T, Balasubramanian V, Gardner RM, Cheung L, Hung G, Granger CB, Kowey P, Rumsfeld JS, Russo AM, True Hills M, Talati N, Nag D, Tsay D, Desai S, Desai M, Mahaffey KW, Turakhia MP, Perez MV; Apple Heart Study Investigators.
Circ Arrhythm Electrophysiol. 2021 Sep 27:CIRCEP121010063. doi: 10.1161/CIRCEP.121.010063. |
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| Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity. |
Reynolds HR, Shaw LJ, Min JK, Page CB, Berman DS, Chaitman BR, Picard MH, Kwong RY, O'Brien SM, Huang Z, Mark DB, Nath RK, Dwivedi SK, Smanio PEP, Stone PH, Held C, Keltai M, Bangalore S, Newman JD, Spertus JA, Stone GW, Maron DJ, Hochman JS.
Circulation. 2021 Sep 28;144(13):1024-1038. doi: 10.1161/CIRCULATIONAHA.120.049755. |
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| Natural History of Patients With Ischemia and No Obstructive Coronary Artery Disease: The CIAO-ISCHEMIA Study. |
Reynolds HR, Picard MH, Spertus JA, Peteiro J, Lopez Sendon JL, Senior R, El-Hajjar MC, Celutkiene J, Shapiro MD, Pellikka PA, Kunichoff DF, Anthopolos R, Alfakih K, Abdul-Nour K, Khouri M, Bershtein L, De Belder M, Poh KK, Beltrame JF, Min JK, Fleg JL, Li Y, Maron DJ, Hochman JS.
Circulation. 2021 Sep 28;144(13):1008-1023. doi: 10.1161/CIRCULATIONAHA.120.046791. |
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| Phenotypic Expression, Natural History and Risk Stratification of Cardiomyopathy Caused by Filamin C Truncating Variants. |
Gigli M, Stolfo D, Graw S, Merlo M, Gregorio C, Chen SN, Dal Ferro M, Paldino A, De Angelis G, Brun F, Jirikowic J, Salcedo EE, Turja S, Fatkin D, Johnson R, van Tintelen JP, Te Riele ASJM, Wilde A, Lakdawala NK, Picard K, Miani D, Muser D, Severini GM, Calkins H, James CA, Murray B, Tichnell C, Parikh VN, Ashley EA, Reuter C, Song J, Judge D, McKenna WJ, Taylor MRG, Sinagra G, Mestroni L.
Circulation. 2021 Sep 30. doi: 10.1161/CIRCULATIONAHA.121.053521. |
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| Epigenetic Age and the Risk of Incident Atrial Fibrillation. |
Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, Skanes AC, Bartz TM, Perez MV, Taylor KD, Lubitz SA, Ellinor PT, Lunetta KL, Pankow JS, Paré G, Sotoodehnia N, Benjamin EJ, Horvath S, Marcus GM.
Circulation. 2021 Sep 30. doi: 10.1161/CIRCULATIONAHA.121.056456. |
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| Substrate Characterization and Outcomes of Ventricular Tachycardia Ablation in TTN (Titin)Cardiomyopathy: A Multicenter Study. |
Enriquez A, Liang J, Smietana J, Muser D, Salazar P, Shah R, Badhwar N, Bogun F, Marchlinski F, Garcia F, Baranchuk A, Tung R, Redfearn D, Santangeli P.
Circ Arrhythm Electrophysiol. 2021 Sep;14(9):e010006. doi: 10.1161/CIRCEP.121.010006. |
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| Dosing of Direct Oral Anticoagulants in Patients with Moderate Chronic Kidney Disease in US Clinical Practice: Results from the Outcomes Registry for Better Informed Treatment of AF (ORBIT-AF II). |
Jackson LR 2nd, Schrader P, Thomas L, Steinberg BA, Blanco R, Allen LA, Fonarow GC, Freeman JV, Gersh BJ, Kowey PR, Mahaffey KW, Naccarelli G, Reiffel J, Singer DE, Peterson ED, Piccini JP; Outcomes Registry for Better Informed Treatment of Atrial Fibrillation (ORBIT-AF) II Investigators and Patients.
Am J Cardiovasc Drugs. 2021 Sep;21(5):553-561. doi: 10.1007/s40256-021-00473-x. |
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| Impact of thoracotomy approach on right ventricular failure and length of stay in left ventricular assist device implants: an intermacs registry analysis. |
Lampert BC, Teuteberg JJ, Cowger J, Mokadam NA, Cantor RS, Benza RL, Ganapathi AM, Myers SL, Hiesinger W, Woo J, Pagani F, Kirklin JK, Whitson BA.
J Heart Lung Transplant. 2021 Sep;40(9):981-989. doi: 10.1016/j.healun.2021.05.022. |
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| Coronavirus disease 2019 in heart transplant recipients: Risk factors, immunosuppression, and outcomes. |
Genuardi MV, Moss N, Najjar SS, Houston BA, Shore S, Vorovich E, Atluri P, Molina M, Chambers S, Sharkoski T, Hsich E, Estep JD, Owens AT, Alexander KM, Chaudhry SP, Garcia-Cortes R, Molina E, Rodrigo M, Wald MJ, Margulies KB, Hanff TC, Zimmer R, Kilic A, Mclean R, Vidula H, Dodd K, Blumberg EA, Mazurek JA, Goldberg LR, Alvarez-Garcia J, Mancini D, Teuteberg JJ, Tedford RJ, Birati EY.
J Heart Lung Transplant. 2021 Sep;40(9):926-935. doi: 10.1016/j.healun.2021.05.006. |
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| Intravascular ultrasound predictors of long-term outcomes following ABSORB bioresorbable scaffold implantation: A pooled analysis of the ABSORB III and ABSORB Japan trials. |
Nishi T, Okada K, Kitahara H, Kameda R, Ikutomi M, Imura S, Hollak MB, Yock PG, Popma JJ, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Ellis SG, Kereiakes DJ, Stone GW, Honda Y, Kimura T; ABSORB III and ABSORB Japan Investigators.
J Cardiol. 2021 Sep;78(3):224-229. doi: 10.1016/j.jjcc.2021.03.005. |
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| Improving Right Ventricular Function by Increasing BMP Signaling with FK506. |
Boehm M, Tian X, Ali MK, Mao Y, Ichimura K, Zhao M, Kuramoto K, Dannewitz Prosseda S, Fajardo G, Dufva MJ, Qin X, Kheyfets VO, Bernstein D, Reddy S, Metzger RJ, Zamanian RT, Haddad F, Spiekerkoetter E.
Am J Respir Cell Mol Biol. 2021 Sep;65(3):272-287. doi: 10.1165/rcmb.2020-0528OC. |
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| Associations of Insulin Resistance With Systolic and Diastolic Blood Pressure: A Study From the HCHS/SOL. |
Quesada O, Claggett B, Rodriguez F, Cai J, Moncrieft AE, Garcia K, Del Rios Rivera M, Hanna DB, Daviglus ML, Talavera GA, Bairey Merz CN, Solomon SD, Cheng S, Bello NA.
Hypertension. 2021 Sep;78(3):716-725. doi: 10.1161/HYPERTENSIONAHA.120.16905. |
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| Renal denervation in hypertension patients: Proceedings from an expert consensus roundtable cosponsored by SCAI and NKF. |
Kandzari DE, Townsend RR, Bakris G, Basile J, Bloch MJ, Cohen DL, East C, Ferdinand KC, Fisher N, Kirtane A, Lee DP, Puckrein G, Rader F, Vassalotti JA, Weber MA, Willis K, Secemsky E.
Catheter Cardiovasc Interv. 2021 Sep;98(3):416-426. doi: 10.1002/ccd.29884. |
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| Long-Term Exposures to Air Pollution and the Risk of Atrial Fibrillation in the Women's Health Initiative Cohort. |
Hart JE, Hohensee C, Laden F, Holland I, Whitsel EA, Wellenius GA, Winkelmayer WC, Sarto GE, Warsinger Martin L, Manson JE, Greenland P, Kaufman J, Albert C, Perez MV.
Environ Health Perspect. 2021 Sep;129(9):97007. doi: 10.1289/EHP7683. Epub 2021 Sep 15. |
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| CTA pulmonary artery enlargement in patients with severe aortic stenosis: Prognostic impact after TAVR. |
Turner VL, Jubran A, Kim JB, Maret E, Moneghetti KJ, Haddad F, Amsallem M, Codari M, Hinostroza V, Mastrodicasa D, Sailer AM, Kobayashi Y, Nishi T, Yeung AC, Watkins AC, Lee AM, Miller DC, Fischbein MP, Fearon WF, Willemink MJ, Fleischmann D.
J Cardiovasc Comput Tomogr. 2021 Sep-Oct;15(5):431-440. doi: 10.1016/j.jcct.2021.03.004. |
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