 SRRR-III update
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The EOI process was a great success! Nine submissions were received, these were independently reviewed by 9 people with a range of expertise. We are pleased to announce the four groups that will be convening over the next 12-18 months to deliver important consensus recommendations as part of the Third Stroke Recovery and Rehabilitation Roundtable.
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If you haven’t read previous SRRR recommendations you should, and you can find them by clicking or scanning the QR code.
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We’re excited to announce the top 4 topics for our next Roundtable. The Task Force leads for these topic areas have put forward a compelling argument for how convening and consensus building around the topics will help advance not just our science but also pathways for better outcomes for our patients. We look forward to updating you on their progress
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Roundtable title: A translational roadmap for the use of precision non-invasive brain stimulation in stroke rehabilitation
The international roundtable for the use of non-invasive brain stimulation (NIBS) in stroke rehabilitation will focus on current evidence for the use of NIBS techniques, such as transcranial magnetic and electrical stimulation, in stroke recovery and will develop a translational pathway forward for these technologies. The aims of this roundtable will be to: 1) develop consensus recommendations for the use of preclinical translational pipelines to accelerate the identification and optimization of NIBS protocols to test in stroke rehabilitation clinical trials; 2) develop a set of guidelines for the testing, validation and reporting of prognostic biomarkers for patient selection and evaluation of precision treatment approaches for NIBS interventions in stroke rehabilitation clinical trials; and 3) develop consensus recommendations for the establishment of large-scale international NIBS clinical trial and observational databases to enable the development and validation of prediction algorithms for clinically efficacious NIBS treatment protocols and biomarkers. These aims will enable the implementation of individualized stroke rehabilitation strategies leveraging NIBS technologies, to maximize post-stroke functional outcomes. Deliverables from this roundtable will consist not only of the above consensus recommendations, but a framework for their clinical translation and an established international consortium of participating investigators and sites to launch this framework.
Roundtable Leads
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Jodi Edwards
Director of the Brain and Heart Nexus Research Program
University of Ottawa
Canada
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Christian Gerloff
Director of the Dept. of Neurology and full professor of neurology
University Medical Center Hamburg Eppendorf
Germany
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Roundtable title: Fatigue after stroke. Towards major breakthroughs
Fatigue is a major debilitating issue, affecting 50% of people living with stroke. It consistently ranks as a top research priority (ranked 4th in 2021 UK priority setting. We need consensus around terminology and measurement tools. PSF is associated with a number of biological and psychological factors, but studies report contradictory results (likely due to limitations of measurement tools). There may be different phenotypes of PSF (e.g., mental vs physical), with different underlying mechanisms and therefore different treatment targets. We will map current understanding of fatigue etiology, including relevant knowledge from other conditions for which fatigue is a problem in order to identify priority areas for future research. There are no effective interventions for fatigue. There are some pharmacological trials in progress (eg for modafinil). Better understanding of possible biological mechanisms will allow us to identify potential candidate drugs. It is highly likely that effective management of PSF fatigue will require a biopsychosocial approach. By bringing together experts from a range of disciplines and reaching consensus about definitions, measurement and key targets for future research, we will provide a clear roadmap for future research that will act to accelerate research activity in this space to achieve major breakthroughs.
Roundtable Leads
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Coralie English
Professor at University of Newcastle and Hunter Medical Research Institute
Australia
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Gillian Mead
Professor of Stroke and Elderly Care Medicine, University of Edinburgh
UK
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Roundtable title: Standardized measurement of lower limb impairment, balance control and walking ability after stroke: The consensus-based core recommendations from the Third Stroke Recovery and Rehabilitation Roundtable Task Force (SRRR III)
Knowledge about recovery of balance control and walking ability is important to select therapies and allow early supported discharge (ESD) for regaining independency in basic and extended ADLs after stroke. Unfortunately, there is no consensus in stroke recovery and rehabilitation trials how to measure lower limb impairment, sitting- and standing balance and hemiplegic gait post stroke making studies incomparable. In line with the first and second SRRR consensus meeting in which we achieved consensus on definitions, clinical outcomes and how to measure quality of movement (QoM) for the paretic upper limb (https://journals.sagepub.com/page/wso/srrr), the third meeting will address the following questions: 1. Which clinical outcomes need to be recommended for measuring lower limb impairment, sitting- and standing balance control and independent walking ability at 3 and 6 months post stroke? 2. Which clinical baseline variables are minimally needed to predict recovery of standing balance control and walking ability at 3 and 6 months post stroke? Which kinetic and kinematic metrics should be recommended as a performance assay to understand recovery in QoM of balance and gait in the first six months after stroke?
Roundtable Leads
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Gert Kwakkel
Department of Rehabilitation Medicine, Amsterdam University Medical Centers, Amsterdam
The Netherlands
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Gert Verheyden
Head of Stroke Rehabilitation Research Team at KU Leuven
Belgium
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Roundtable title: Taking control of the ‘control intervention’ in stroke recovery research .
Benefit of an experimental intervention (pharmacological/device/behavioural/multi-component) is established when the outcome is deemed better than a control intervention. Appropriate control intervention design is therefore critical, but to date has received little attention in stroke recovery literature. More careful and systematic selection of control interventions will increase the scientific rigor of stroke recovery trials. The proposed SRRR taskforce on control interventions will develop consensus recommendations to guide control intervention design, description, and reporting. In line with previous roundtable outputs, resources will be produced to support the ISRRA community to adopt and adhere to the recommendations.
Roundtable Leads
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Kate Hayward
Senior Research Fellow,
University of Melbourne and Florey Institute of Neuroscience and Mental Health
Australia
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Catherine Lang
Professor of Physical Therapy and Neurology, and Occupational Therapy Associate Director
Washington University in St Louis, MO
USA
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Keep note of our upcoming site:
www.strokerecoveryalliance.com
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For any queries about ISRRA
(e.g. membership, upcoming events, research papers published
by our team):
Contact us at:
admin@strokerecoveryalliance.com
Our email is being monitored by more than one of our members
on a daily basis. We will try to get back to you ASAP!
DON'T LET US GO TO YOUR JUNK!
Remember to add admin@strokerecoveryalliance.com to your safe email list.
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Editors from both the International Journal of Stroke and Stroke are looking for suggestions for high quality reviews. As a community committed to advancing stroke recovery and rehabilitation science and practice, it’s up to us to promote our field. To do that, we need to be pro-active in suggesting topics and review teams for these calls.
If you have an idea for a review (that you don’t need to lead), please send your ‘pitch’ to our admin email and we will forward it to the journal editors.
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An effective pitch will:
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Outline why a review of the topic is important and timely
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Propose a lead or several authors who would produce a high-quality review (narrative, scoping, systematic)
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May suggest the scope of the review
Consider the journals calling for reviews – it is unlikely that your idea will get advanced if you propose a review that has recently been published either in these journal or in other journals.
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If you have a review that is almost complete that you think is novel, timely and of excellent quality, you are welcome to submit that idea. Do state the expected timeline to completion of the review in your email, providing information about Topic, authors, and scope.
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Huge thanks for spreading the word!
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Elizabeth Lynch:
For talking about the Centres of Clinical Excellence at The Stroke Society of Australasia Conference
Julie Bernhardt:
For talking at American Congress of Rehab Medicine about collaborations – including a pitch to join ISRRA
AND
For talking about ISRRA at the World Stroke Congress on Oct 28th, 2021
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If you have been able to promote ISRRA please let us know!
You can also contact us if you require materials such as PPT presentations to facilitate promotion
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Share link to become an ISRRA member by clicking any of the following icons:
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