ISAPP Newsletter – March 2022

The research shared in this newsletter ranges from animal to human health, as well as to basic research -- showing the variety of questions being addressed by scientists studying the microbiome, probiotics and related substances. Below you will find a study on the gut microbiomes of domestic versus feral horses, as well as a Q&A with Prof. Maria Marco, whose lab recently discovered a novel ‘hybrid’ metabolism used by a type of lactic acid bacteria.

Prof. Sarah Lebeer recently published new results showing a group of three bacterial strains that reduced inflammation and acne lesions on the skin.

We also bring you a special resource from Prof. Dan Tancredi: a statistics mini-tutorial, which sets the record straight on proper use of p-values.

Our featured resource this month is our popular prebiotics infographic, available in 14 languages!

We invite you to sign up for an upcoming ISAPP webinar on the prebiotic potential of polyphenols. Find the details below.

Domestic horses from different geographical locations harbor antibiotic resistant gut bacteria, unlike their wild counterparts

Dr. Gabriel Vinderola shares how he and a group of international colleagues, including fellow ISAPP board member Prof. Seppo Salminen, started a collaboration to study the gut microbiomes of domestic and feral horses. The groups of horses showed differences in their gut microbial communities, including their fecal resistomes.

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Bacterial genes lead researchers to discover a new way that lactic acid bacteria can make energy and thrive in their environments

Previously, researchers found something unexpected when studying a type of lactic acid bacteria called Lactiplantibacillus plantarum: they contained genes for making energy in a way that had not been previously documented. Prof. Maria Marco's lab recently published on a new kind of ‘hybrid’ metabolism in these bacteria, with features of both fermentation and respiration. In this blog post we share a Q&A with Prof. Marco.

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Promising skin probiotic could be a way to reduce antibiotic treatments for acne

Lactobacilli are frequently associated with the gut microbial community, but they may have important applications for skin as well. Prof. Sarah Lebeer’s lab recently published a study showing that three strains of lactobacilli, delivered in a topical cream, were able to modulate the skin microbiome, and reduce skin inflammation and acne lesions. The work shows the progress being made in the probiotic field in non-gut applications.

See here

Mini-tutorial on statistical analysis: Correcting a common misinterpretation of p-values

p-values are important for knowing whether a scientific study can inform a particular decision. In this blog post, Prof. Dan Tancredi cautions against a frequently observed misuse of p-values and explains how to use small p-values to evaluate whether a null hypothesis is plausible.

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This month's featured resource

Our featured resource this month is our prebiotics infographic, which provides the ISAPP definition of prebiotics and concisely summarizes their potential health effects. Thanks to ISAPP’s volunteer translators, this infographic is now available to view in 14 languages.

See here

Webinar: The prebiotic potential of polyphenols

Prebiotics offer tremendous potential for modifying the gut microbiota for health. Prebiotics such as FOS, GOS and inulin are well established, but research is accumulating on other candidate prebiotics as well. In this open access, free ISAPP webinar, Prof. Daniele Del Rio (University of Parma, Italy) and Prof. Yves Desjardins (Université Laval, Canada) will share their wealth of knowledge of polyphenols by addressing polyphenols in plants, evidence that polyphenols provide health benefits, how gut microbiota modulates the bioactivity of dietary polyphenols, and whether available knowledge about polyphenols meets expectations for prebiotic substances. Join for the talks and Q&A moderated by co-hosts Prof. Bob Hutkins and Dr. Maria Weise (TNO). The live webinar will be held April 28, 10-11 AM Eastern Daylight Time. Registration is required. The recorded webinar will be posted for those unable to make the live event.

See here

ISAPP is the International Scientific Association for Probiotics and Prebiotics.
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