Electrodes Placed in Brain May Offer Way of ‘Sensing’ Parkinson’s Arrival
Sep 16, 2020 07:00 am | Diana Campelo Delgado
 Engineers with Michigan State University (MSU) are developing diamond-based electrodes that might detect early warning signs of neurodegenerative diseases such as Parkinson’s in a living brain. MSU researchers Wen Li and Erin Purcell have received $3.4 million in funding from the National Institutes of Health and an MSU Strategic Partnership Grant to conduct preclinical work evaluating the safety, durability, […]
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Supernus Submits SPN-830 Apomorphine Infusion Pump for FDA Approval
Sep 16, 2020 07:00 am | Marisa Wexler
 Supernus Pharmaceuticals has submitted a new drug application to the U.S. Food and Drug Administration (FDA) seeking approval of SPN-830, its apomorphine infusion pump, the company said. If approved, the pump will be used for the continuous treatment of on-off episodes in adults with Parkinson’s disease who continue to experience motor symptoms after treatment with oral levodopa and […]
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Kynmobi Safe, Effective for ‘Off’ Periods Over Long Term, Ongoing Trial Reports
Sep 15, 2020 07:00 am | Marisa Wexler
 Sunovion‘s Kynmobi (apomorphine hydrochloride), a sublingual film treatment for “off” episodes in people with Parkinson’s disease, has a manageable safety profile and maintains efficacy over up to nearly a year of use, interim data from an ongoing Phase 3 trial show. Findings were presented at MDS Virtual Congress 2020 in the study, “A Long-Term Safety, Tolerability, […]
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Research Shows How PARK7 Gene Mutations Cause Early Onset Parkinson’s
Sep 15, 2020 07:00 am | Steve Bryson PhD
 Mutations in the PARK7 gene, known to cause early onset Parkinson’s disease, result in low levels of a protein called DJ-1 that is essential for nerve cell health, a study revealed. In fixing a protein processing malfunction in cells derived from members of a single family who carried a particular mutation in this gene, a team […]
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4th-generation DBS System, Vercise Genus, Available in Europe
Sep 14, 2020 07:00 am | Marisa Wexler
 Vercise Genus, a fourth-generation system for deep brain stimulation (DBS) made by Boston Scientific, has received CE marking and is now commercially available in Europe. A treatment approach for Parkinson’s disease, DBS involves surgically implanting a neurostimulator to deliver electrical impulses to targeted regions of the brain that control movement, pain, mood, and the like. […]
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Disturbed Sleep Tied to Cognitive Problems in Parkinson’s Patients
Sep 14, 2020 07:00 am | Ines Martins, PhD
 Disturbed sleep, like that due to sleep apnea, significantly associates with poorer cognition in Parkinson’s disease patients, particularly in the domains of attention, executive function, and memory, a study reported. The study, “Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s Disease,” was published in the journal Frontiers in Neuroscience. In addition to […]
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Preventing Conductor Malfunction During a ‘Perfect Storm’
Sep 11, 2020 09:00 am | Dr. C
 It was one of those “perfect storm” weeks, when everything came together in a cumulative effect to make life miserable. Too much stress on my system makes it exceedingly difficult to use the conductor due to malfunctions. This only happens to me a few times a year, but it is disabling when it does. The […]
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Hidrox, an Olive Extract, Eased Parkinson’s Symptoms in Mice, Study Finds
Sep 11, 2020 07:00 am | Ines Martins, PhD
 Hidrox, a compound extracted from olives, can significantly ease Parkinson’s motor symptoms, reduce alpha synuclein buildup, and slow neurodegeneration in animal models of the disease, a recent study has found. Though Hidrox is known mostly for its antioxidant effects, its benefits in Parkinson’s went beyond a decline in oxidative stress; brain inflammation, inflammasome signaling, and […]
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Newly Launched Valted Seq Working to Discover Disease Pathways, Biomarkers
Sep 11, 2020 07:00 am | Forest Ray, PhD
 D&D Pharmatech has launched a new company called Valted Seq, aimed at discovering pathways and biomarkers relevant to neurodegenerative diseases such as Parkinson’s. To this end, the company claims in a press release to have created the world’s largest repository of single-cell sequencing data. This data comes from high-quality, clinically characterized brain tissues of patients […]
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What the ‘Sandwich Generation’ Tells Us About Heroes
Sep 10, 2020 03:00 pm | Sherri Woodbridge
 I heard something recently that was new to me — that we are living in “sandwich times.” In other words, this is the “sandwich generation.” It’s a time in history when many are simultaneously caring for both a child at home and a parent. Caring for a so-called normal child or adult can be difficult […]
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