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Cardiovascular Medicine Monthly Newsletter October 2020 | View Online
Hearty News
Cardiovascular Medicine Monthly Newsletter
October 2020
Appointments and Promotions
Faculty
Promotions
Phillip Yang MD was promoted to Professor of Medicine (MCL - Cardiovascular Medicine) on October 1, 2020. 
Welcome back to Stanford!
Hannah Valantine MD MRCP is back at Stanford after serving as the Chief Officer for Scientific Workforce Diversity at the NIH for the last 6 years. She is resuming her appointment as Professor (MCL - Cardiovascular Medicine) as of October 1, 2020. Welcome back, Hannah!
Congratulations and good luck!
Myriam Amsallem MD PhD has accepted a position at Facebook as Clinical Lead starting October 25, 2020.
Robert Wirka MD has accepted a position as Assistant Professor of Medicine in the Department of Cell Biology and Physiology at University of North Carolina.
New Sponsored Awards
Subcontracts
Phillip Yang
University of Miami (Subcontract)
“A Phase IIB, randomized, placebo-controlled, multicenter study of the comparative efficacy and safety of transendocardial injection of allogeneic mesenchymal stem cells versus placebo in patients with non-ischemic dilated cardiomyopathy (DCM II Trial)”
May 1, 2020 – April 30, 2024
Clinical Trials
David Lee
Medtronic Vascular, Inc. (Clinical trial)
“Global Clinical Study of Renal Denervation in the distal main and first order branch renal arteries using the Symplicity SpyralTM multi-electrode renal denervation system (SPYRAL DYSTAL)
September 1, 2020 – August 31, 2025
Ronald Witteles
Ionis Pharmaceuticals, Inc. (Clinical trial)
“Phase 3 Global, Double-Blind, Randomized, Placebo‑Controlled Study to Evaluate the Efficacy and Safety of ION-682884 in Patients with Transthyretin‑Mediated Amyloid Cardiomyopathy (ATTR CM) [CA]”
October 7, 2020 – October 6, 2024
Staff Updates
New appointments
Sarah Abramowitz, Life Science Research Professional 1, is working in Dr. Wheeler's Lab on models of rare disease. Sarah started on September 28th.
Yuko Tada, Basic Life Research Scientist, is working with Dr. Phillip Yang on various MRI research projects. Yuko started on October 4th.
Our Team in the News
SEP 11, 2020
Read more
Drs. June Rhee and Joseph Wu along with other researchers find potential cure for deadly iron-overload disease.
View More Team News
Cardiology Fellowship Program
Fellowship Awards and Publications
Awards and Grants
Jennifer Woo received a NIH F32 on Novel Computational Methods for Detecting Early Right Ventricular Failure in the Tetralogy of Fallot Population starting September 1st.
Publications
The Impact of Novel Coronavirus COVID‐19 on Non‐Communicable Disease Patients and Health Systems: A Review
Chang AY, Cullen MR, Harrington RA, Barry M.
Journal of Internal Medicine. 2020 5 Oct. doi: 10.1111/joim.13184.
Trends in Readmission and Mortality Rates Following Heart Failure Hospitalization in the Veterans Affairs Health Care System From 2007 to 2017.
Parizo JT, Kohsaka S, Sandhu AT, Patel J, Heidenreich PA.
JAMA Cardiol. 2020 Sep 1;5(9):1042-1047. doi: 10.1001/jamacardio.2020.2028.
Wearables for arrhythmia care: Challenges and future prospects.
Sarraju A, Turakhia M.
CV Digital Health Journal. 2020 Sept 20. doi.org/10.1016/j.cvdjj.2020.09.001
Machine learning and atherosclerotic cardiovascular disease risk prediction in a multi-ethnic population.
Ward A, Sarraju A, Chung, S. et al. 
npj Digit. Med. 3, 125 (2020 Sep 23). doi.org/10.1038/s41746-020-00331-1
Upcoming Events and Conferences
Register today!
MyHeart Counts 5K/10K is going virtual this year!

Rescheduled dates:
Saturday, October 24, 2020
Sunday, October 25, 2020
 
CV Med Quarterly Socials – On HOLD until further notice
Featured Cardiovascular Medicine Conferences
All conferences via Zoom until further notice.
Frontiers in CV Science
Tuesdays | 12:30pm - 1:30pm
Li Ka Shing Center, Stanford
Starting back on September 15, 2020

 
Cardiology Grand Rounds 
Thursdays | 8:00am - 9:00am
Falk Cardiovascular Research Center
Library
Starting back on September 17, 2020
 
Additional Cardiovascular Medicine CME information:
https://med.stanford.edu/cme/find-a-course/cvmedicine.html
Complete list of Stanford CME courses:
https://med.stanford.edu/cme/learning-opportunities/live.html
Additional Conferences October - December:
https://med.stanford.edu/cme/learning-opportunities/live.html
Cardiovascular Research Foundation - Transcatheter CV Therapeutics 2020
Dates: October 14-18, 2020
Register: TCT 2020
31st Annual Cardiovascular Interventions 
Date: November 10-13, 2020
Register: CV Interventions
American Heart Association - Scientific Sessions
Date: November 13-17, 2020
Register: AHA
Keystone Symposia
Date: Various dates
Register: Keystone
Upcoming Funding Opportunities
Need help applying for a grant?
If you are thinking about applying for a grant, email Pete Silva.
AHA grants:
https://professional.heart.org/professional/ResearchPrograms
/ApplicationInformation/UCM_316909_Application-Information.jsp
Continuous Submissions
Intermountain-Stanford Collaboration Grant
Request for Letters of Intent for Travel Grants Letters of intent may be submitted at any time.
Applicants will be notified within 21 days of submission.
Award Amount: Reimburse actual costs
Intermountain-Stanford
Cardiovascular Imaging Postdoctoral Fellowship Training at Stanford (T32)
CV Imaging
Training in Myocardial Biology at Stanford (T32)
TIMBS
Mechanism and Innovation in Cardiovascular Disease (T32)
Vascular 
November
R01 - Renewal/Resubmission/Revision
Clinical Trial Not Allowed
Deadline – November 5, 2020 | PA-20-185
Clinical Trial Required
Deadline – November 5, 2020 | PA-20-183
K08 Career Development Grants - Renewal/Resubmission/Revision
Clinical Trial Not Allowed
Deadline – November 12, 2020 | PA-20-203
Clinical Trial Required
Deadline – November 12, 2020 | PA-20-202
K99 Pathway to Independence - Renewal/Resubmission/Revision
Clinical Trial Not Allowed
Deadline – November 12, 2020 | PA-20-188
Clinical Trial Required
Deadline – November 12, 2020 | PA-20-187
December
F32 - Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship
Deadline – December 8, 2020 | PA-19-188
January/February
R01 - New application
Clinical Trial Not Allowed
Deadline – February 5, 2021 | PA-20-185
Clinical Trial Required
Deadline – February 5, 2021 | PA-20-183
K08 Career Development Grants - New application
Clinical Trial Not Allowed
Deadline – February 12, 2021 | PA-20-203
Clinical Trial Required
Deadline – February 12, 2021 | PA-20-202
K99 Pathway to Independence - New application
Clinical Trial Not Allowed
Deadline – February 12, 2021 | PA-20-188
Clinical Trial Required
Deadline – February 12, 2021 | PA-20-187
Faculty Publications
Included in this newsletter are publications from our cardiovascular medicine faculty for September 2020.
SEPTEMBER
Hydroxychloroquine, Coronavirus Disease 2019, and QT Prolongation.
Bonow RO, Hernandez AF, Turakhia M.
JAMA Cardiol. 2020 Sep 1;5(9):986-987. doi: 10.1001/jamacardio.2020.1782.
Trends in Readmission and Mortality Rates Following Heart Failure Hospitalization in the Veterans Affairs Health Care System From 2007 to 2017.
Parizo JT, Kohsaka S, Sandhu AT, Patel J, Heidenreich PA.
JAMA Cardiol. 2020 Sep 1;5(9):1042-1047. doi: 10.1001/jamacardio.2020.2028.
Sex-specific genetic effects across biomarkers.
Flynn E, Tanigawa Y, Rodriguez F, Altman RB, Sinnott-Armstrong N, Rivas MA.
Eur J Hum Genet. 2020 Sep 1. doi: 10.1038/s41431-020-00712-w.
Integrating the ABC-Bleeding Risk Score Into Practice.
Yong CM, Bittl JA.
JAMA Netw Open. 2020 Sep 1;3(9):e2016126. doi: 10.1001/jamanetworkopen.2020.16126.
Risk Prediction Tool for Assessing the Probability of Death or Myocardial Infarction in Patients With Stable Coronary Artery Disease.
Boden WE, Hartigan PM, Mancini J, Teo KK, Chaitman BR, Maron DJ, Kostuk WJ, Hartigan JA, Dada M, Spertus JA, Bates ER, Weintraub WS; COURAGE Trial Investigators.
Am J Cardiol. 2020 Sep 1;130:1-6. doi: 10.1016/j.amjcard.2020.05.046.
Independent and cumulative association of clinical and morphological heart failure with long-term outcome after percutaneous coronary intervention.
Kimura M, Kohno T, Sawano M, Heidenreich PA, Ueda I, Takahashi T, Matsubara T, Ueno K, Hayashida K, Yuasa S, Ohki T, Fukuda K, Kohsaka S.
J Cardiol. 2020 Sep 1:S0914-5087(20)30208-2. doi: 10.1016/j.jjcc.2020.06.014.
Cardiac procedural deferral during the coronavirus (COVID-19) pandemic.
Yong CM, Ang L, Welt FGP, Gummidipundi S, Henry TD, Pinto DS, Cox D, Wang P, Asch S, Mahmud E, Fearon WF; Society for Cardiovascular Angiography and Interventions (SCAI) and the American College of Cardiology (ACC) Interventional Council.
Catheter Cardiovasc Interv. 2020 Sep 3. doi: 10.1002/ccd.29262.
Invasive or Conservative Strategy for Stable Coronary Disease. Reply.
Maron DJ, Hochman JS.
N Engl J Med. 2020 Sep 3;383(10):e66. doi: 10.1056/NEJMc2024008.
Apelin increases atrial conduction velocity, refractoriness, and prevents inducibility of atrial fibrillation.
Kim YM, Lakin R, Zhang H, Liu J, Sachedina A, Singh M, Wilson E, Perez M, Verma S, Quertermous T, Olgin J, Backx PH, Ashley EA.
JCI Insight. 2020 Sep 3;5(17):126525. doi: 10.1172/jci.insight.126525.
Scaffold underexpansion and late lumen loss after bioresorbable scaffold implantation: Insights from ABSORB JAPAN trial.
Okada K, Honda Y, Kitahara H, Ikutomi M, Kameda R, Brooke Hollak M, Yock PG, Popma JJ, Kusano H, Cheong WF, Sudhir K, Fitzgerald PJ, Kimura T; ABSORB Japan Investigators.
Int J Cardiol Heart Vasc. 2020 Sep 4;31:100623. doi: 10.1016/j.ijcha.2020.100623.
Copy number variant hotspots in Han Taiwanese population induced pluripotent stem cell lines - lessons from establishing the Taiwan human disease iPSC Consortium Bank.
Huang CY, Li LH, Hsu WT, Cheng YC, Nicholson MW, Liu CL, Ting CY, Ko HW, Syu SH, Wen CH, Yan Z, Huang HP, Su HL, Chiang PM, Shen CN, Chen HF, Yen BLJ, Lu HE, Hwang SM, Chiou SH, Ho HN, Wu JY, Kamp TJ, Wu JC, Hsieh PCH.
J Biomed Sci. 2020 Sep 4;27(1):92. doi: 10.1186/s12929-020-00682-7.
Chromosome 1q21.2 and additional loci influence risk of spontaneous coronary artery dissection and myocardial infarction.
Saw J, Yang ML, Trinder M, Tcheandjieu C, Xu C, Starovoytov A, Birt I, Mathis MR, Hunker KL, Schmidt EM, Jackson L, Fendrikova-Mahlay N, Zawistowski M, Brummett CM, Zoellner S, Katz A, Coleman DM, Swan K, O'Donnell CJ; Million Veteran Program, Zhou X, Li JZ, Gornik HL, Assimes TL, Stanley JC, Brunham LR, Ganesh SK.
Nat Commun. 2020 Sep 4;11(1):4432. doi: 10.1038/s41467-020-17558-x.
Associations Between Depressive Symptoms and HFpEF-Related Outcomes.
Chandra A, Alcala MAD, Claggett B, Desai AS, Fang JC, Heitner JF, Liu J, Pitt B, Solomon SD, Pfeffer MA, Lewis EF.
JACC Heart Fail. 2020 Sep 4:S2213-1779(20)30386-3. doi: 10.1016/j.jchf.2020.06.010.
An Irregular Rhythm: What Is the Mechanism?
Higuchi S, Kumar UN, Badhwar N, Tchou P, Scheinman MM.
JACC Clin Electrophysiol. 2020 Sep;6(9):1205-1211. doi: 10.1016/j.jacep.2020.08.006.
iPSC Modeling of RBM20-Deficient DCM Identifies Upregulation of RBM20 as a Therapeutic Strategy.
Briganti F, Sun H, Wei W, Wu J, Zhu C, Liss M, Karakikes I, Rego S, Cipriano A, Snyder M, Meder B, Xu Z, Millat G, Gotthardt M, Mercola M, Steinmetz LM.
Cell Rep. 2020 Sep 8;32(10):108117. doi: 10.1016/j.celrep.2020.108117.
Multi-task deep learning for cardiac rhythm detection in wearable devices.
Torres-Soto J, Ashley EA.
NPJ Digit Med. 2020 Sep 9;3:116. doi: 10.1038/s41746-020-00320-4.
Management of Coronary Disease in Patients with Advanced Kidney Disease. Reply.
Bangalore S, Maron DJ, Hochman JS.
N Engl J Med. 2020 Sep 10;383(11):1091-1092. doi: 10.1056/NEJMc2024023.
Primary Prevention Trial Designs Using Coronary Imaging: A National Heart, Lung, and Blood Institute Workshop.
Greenland P, Michos ED, Redmond N, Fine LJ, Alexander KP, Ambrosius WT, Bibbins-Domingo K, Blaha MJ, Blankstein R, Fortmann SP, Khera A, Lloyd-Jones DM, Maron DJ, Min JK, Muhlestein JB, Nasir K, Sterling MR, Thanassoulis G.
JACC Cardiovasc Imaging. 2020 Sep 11:S1936-878X(20)30650-1. doi: 10.1016/j.jcmg.2020.06.042.
The relationship between circulating lipids and breast cancer risk: A Mendelian randomization study.
Johnson KE, Siewert KM, Klarin D, Damrauer SM; VA Million Veteran Program, Chang KM, Tsao PS, Assimes TL, Maxwell KN, Voight BF.
PLoS Med. 2020 Sep 11;17(9):e1003302. doi: 10.1371/journal.pmed.1003302.
Transcriptomic signatures across human tissues identify functional rare genetic variation.
Ferraro NM, Strober BJ, Einson J, Abell NS, Aguet F, Barbeira AN, Brandt M, Bucan M, Castel SE, Davis JR, Greenwald E, Hess GT, Hilliard AT, Kember RL, Kotis B, Park Y, Peloso G, Ramdas S, Scott AJ, Smail C, Tsang EK, Zekavat SM, Ziosi M, Aradhana; TOPMed Lipids Working Group, Ardlie KG, Assimes TL, Bassik MC, Brown CD, Correa A, Hall I, Im HK, Li X, Natarajan P; GTEx Consortium, Lappalainen T, Mohammadi P, Montgomery SB, Battle A.
Science. 2020 Sep 11;369(6509):eaaz5900. doi: 10.1126/science.aaz5900.
Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity.
McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL Jr, Kass RS, Cashman JR, Mercola M.
Cell Stem Cell. 2020 Sep 12:S1934-5909(20)30399-4. doi: 10.1016/j.stem.2020.08.003.
Subclinical Heart Dysfunction in Relation to Metabolic and Inflammatory Markers: a Community-Based Study.
Cauwenberghs N, Sabovčik F, Eline V, Kobayashi Y, Haddad F, Budts W, Kuznetsova T.
Am J Hypertens. 2020 Sep 12:hpaa150. doi: 10.1093/ajh/hpaa150.
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.
Olivotto I, Oreziak A, Barriales-Villa R, Abraham TP, Masri A, Garcia-Pavia P, Saberi S, Lakdawala NK, Wheeler MT, Owens A, Kubanek M, Wojakowski W, Jensen MK, Gimeno-Blanes J, Afshar K, Myers J, Hegde SM, Solomon SD, Sehnert AJ, Zhang D, Li W, Bhattacharya M, Edelberg JM, Waldman CB, Lester SJ, Wang A, Ho CY, Jacoby D; EXPLORER-HCM study investigators.
Lancet. 2020 Sep 12;396(10253):759-769. doi: 10.1016/S0140-6736(20)31792-X.
Association of Health Status Scores With Cardiovascular and Limb Outcomes in Patients With Symptomatic Peripheral Artery Disease: Insights From the EUCLID (Examining Use of Ticagrelor in Symptomatic Peripheral Artery Disease) Trial.
Rymer JA, Mulder H, Smolderen KG, Hiatt WR, Conte MS, Berger JS, Norgren L, Mahaffey KW, Baumgartner I, Fowkes FG, Katona BG, Rockhold F, Jones WS, Patel MR.
J Am Heart Assoc. 2020 Sep 13:e016573. doi: 10.1161/JAHA.120.016573.
When is Coronary Revascularization Complete?
Fearon WF, Ahn JM.
Circ Cardiovasc Interv. 2020 Sep;13(9):e009889. doi: 10.1161/CIRCINTERVENTIONS.120.009889. 
Temporal Trend of Age at Diagnosis in Hypertrophic Cardiomyopathy: An Analysis of the International Sarcomeric Human Cardiomyopathy Registry.
Canepa M, Fumagalli C, Tini G, Vincent-Tompkins J, Day SM, Ashley EA, Mazzarotto F, Ware JS, Michels M, Jacoby D, Ho CY, Olivotto I; SHaRe Investigators.
Circ Heart Fail. 2020 Sep;13(9):e007230. doi: 10.1161/CIRCHEARTFAILURE.120.007230.
Using Discontinuity to Cross the Quality Chasm.
Heidenreich PA.
Circ Cardiovasc Interv. 2020 Sep;13(9):e009887. doi: 10.1161/CIRCINTERVENTIONS.120.009887.
Procedural Patterns and Safety of Atrial Fibrillation Ablation: Findings From Get With The Guidelines-Atrial Fibrillation.
Loring Z, Holmes DN, Matsouaka RA, Curtis AB, Day JD, Desai N, Ellenbogen KA, Feld GK, Fonarow GC, Frankel DS, Hurwitz JL, Knight BP, Joglar JA, Russo AM, Sidhu MS, Turakhia MP, Lewis WR, Piccini JP.
Circ Arrhythm Electrophysiol. 2020 Sep;13(9):e007944. doi: 10.1161/CIRCEP.119.007944.
Association of Hypertension and Arterial Blood Pressure on Limb and Cardiovascular Outcomes in Symptomatic Peripheral Artery Disease: The EUCLID Trial.
Fudim M, Hopley CW, Huang Z, Kavanagh S, Rockhold FW, Baumgartner I, Berger JS, Blomster JI, Fowkes FGR, Katona BG, Mahaffey KW, Norgren L, Ostrom C, Patel MR, Jones WS, Hiatt WR.
Circ Cardiovasc Qual Outcomes. 2020 Sep;13(9):e006512. doi: 10.1161/CIRCOUTCOMES.120.006512.
Trends in Left Ventricular Ejection Fraction for Patients With a New Diagnosis of Heart Failure.
Tisdale RL, Haddad F, Kohsaka S, Heidenreich PA.
Circ Heart Fail. 2020 Sep;13(9):e006743. doi: 10.1161/CIRCHEARTFAILURE.119.006743.
A Novel Recessive Mutation in SPEG Causes Early Onset Dilated Cardiomyopathy.
Levitas A, Muhammad E, Zhang Y, Perea Gil I, Serrano R, Diaz N, Arafat M, Gavidia AA, Kapiloff MS, Mercola M, Etzion Y, Parvari R, Karakikes I.
PLoS Genet. 2020 Sep 14;16(9):e1009000. doi: 10.1371/journal.pgen.1009000.
Single-Cell RNA-seq Unveils Unique Transcriptomic Signatures of Organ-Specific Endothelial Cells.
Paik DT, Tian L, Williams IM, Rhee S, Zhang H, Liu C, Mishra R, Wu SM, Red-Horse K, Wu JC.
Circulation. 2020 Sep 15. doi: 10.1161/CIRCULATIONAHA.119.041433.
Current Evidence and Recommendations for Coronary CTA First in Evaluation of Stable Coronary Artery Disease.
Poon M, Lesser JR, Biga C, Blankstein R, Kramer CM, Min JK, Noack PS, Farrow C, Hoffman U, Murillo J, Nieman K, Shaw LJ.
J Am Coll Cardiol. 2020 Sep 15;76(11):1358-1362. doi: 10.1016/j.jacc.2020.06.078.
Readability of Online Patient Educational Materials for Coronary Artery Calcium Scans and Implications for Health Disparities.
Rodriguez F, Ngo S, Baird G, Balla S, Miles R, Garg M.
J Am Heart Assoc. 2020 Sep 15;9(18):e017372. doi: 10.1161/JAHA.120.017372.
Association of Adverse Pregnancy Outcomes With Risk of Atherosclerotic Cardiovascular Disease in Postmenopausal Women.
Søndergaard MM, Hlatky MA, Stefanick ML, Vittinghoff E, Nah G, Allison M, Gemmill A, Van Horn L, Park K, Salmoirago-Blotcher E, Sattari M, Sealy-Jefferson S, Shadyab AH, Valdiviezo C, Manson JE, Parikh NI.
JAMA Cardiol. 2020 Sep 16. doi: 10.1001/jamacardio.2020.4097.
A Path Forward.
Elkind MSV, Harrington RA, Lloyd-Jones DM.
J Am Heart Assoc. 2020 Sep 17:e018288. doi: 10.1161/JAHA.120.019210.
COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives.
Nishiga M, Wang DW, Han Y, Lewis DB, Wu JC.
Nat Rev Cardiol. 2020 Sep;17(9):543-558. doi: 10.1038/s41569-020-0413-9. 
Pulling at the heart: COVID-19, race/ethnicity and ongoing disparities.
Chin-Hong P, Alexander KM, Haynes N, Albert MA; Association of Black Cardiologists.
Nat Rev Cardiol. 2020 Sep;17(9):533-535. doi: 10.1038/s41569-020-0416-6.
Guidance for rebooting electrophysiology through the COVID-19 pandemic from the Heart Rhythm Society and the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology: Endorsed by the American College of Cardiology.
Lakkireddy DR, Chung MK, Deering TF, Gopinathannair R, Albert CM, Epstein LM, Harding CV, Hurwitz JL, Jeffery CC, Krahn AD, Kusumoto FM, Lampert R, Mansour M, Natale A, Patton KK, Seiler A, Shah MJ, Wang PJ, Russo AM.
Heart Rhythm. 2020 Sep;17(9):e242-e254. doi: 10.1016/j.hrthm.2020.06.012. 
Relative and Absolute Risk Reductions in Cardiovascular and Kidney Outcomes With Canagliflozin Across KDIGO Risk Categories: Findings From the CANVAS Program.
Neuen BL, Ohkuma T, Neal B, Matthews DR, de Zeeuw D, Mahaffey KW, Fulcher G, Blais J, Li MBiostat Q, Jardine MJ, Perkovic V, Wheeler DC.
Am J Kidney Dis. 2020 Sep 21:S0272-6386(20)30923-9. doi: 10.1053/j.ajkd.2020.06.018.
Decreased lymphatic HIF-2α accentuates lymphatic remodeling in lymphedema.
Jiang X, Tian W, Granucci EJ, Tu AB, Kim D, Dahms P, Pasupneti S, Peng G, Kim Y, Lim AH, Espinoza FH, Cribb M, Dixon JB, Rockson SG, Semenza GL, Nicolls MR.
J Clin Invest. 2020 Sep 21:136164. doi: 10.1172/JCI136164.
Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the CASCADE FH Registry.
de Ferranti SD, Shrader P, Linton MF, Knowles JW, Hudgins LC, Benuck I, Kindt I, O'Brien EC, Peterson AL, Ahmad ZS, Clauss S, Duell PB, Shapiro MD, Wilemon K, Gidding SS, Neal W.
J Pediatr. 2020 Sep 22:S0022-3476(20)31175-6. doi: 10.1016/j.jpeds.2020.09.042.
Avoiding misdiagnosis: expert consensus recommendations for the suspicion and diagnosis of transthyretin amyloidosis for the general practitioner.
Gertz M, Adams D, Ando Y, Beirão JM, Bokhari S, Coelho T, Comenzo RL, Damy T, Dorbala S, Drachman BM, Fontana M, Gillmore JD, Grogan M, Hawkins PN, Lousada I, Kristen AV, Ruberg FL, Suhr OB, Maurer MS, Nativi-Nicolau J, Quarta CC, Rapezzi C, Witteles R, Merlini G.
BMC Fam Pract. 2020 Sep 23;21(1):198. doi: 10.1186/s12875-020-01252-4.
Risk factors for early development of cardiac allograft vasculopathy by intravascular ultrasound.
Moayedi Y, Fan CPS, Tremblay-Gravel M, Miller RJ, Kawana M, Henricksen E, Parizo J, Wainwright R, Fearon WF, Ross HJ, Khush KK, Teuteberg JJ.
Clin Transplant. 2020 Sep 24:e14098. doi: 10.1111/ctr.14098.
Adjustment For Social Risk Factors Does Not Meaningfully Affect Performance On Medicare's MIPS Clinician Cost Measures.
Sandhu AT, Bhattacharya J, Lam J, Bounds S, Luo B, Moran D, Uwilingiyimana AS, Fenson D, Choradia N, Do R, Feinberg L, MaCurdy T, Nagavarapu S.
Health Aff (Millwood). 2020 Sep;39(9):1495-1503. doi: 10.1377/hlthaff.2020.00440.
Routine Revascularization Versus Initial Medical Therapy for Stable Ischemic Heart Disease: A Systematic Review and Meta-Analysis of Randomized Trials.
Bangalore S, Maron DJ, Stone GW, Hochman JS.
Circulation. 2020 Sep;142(9):841-857. doi: 10.1161/CIRCULATIONAHA.120.048194.
Single-Cell Transcriptomic Profiling of Vascular Smooth Muscle Cell Phenotype Modulation in Marfan Syndrome Aortic Aneurysm.
Pedroza AJ, Tashima Y, Shad R, Cheng P, Wirka R, Churovich S, Nakamura K, Yokoyama N, Cui JZ, Iosef C, Hiesinger W, Quertermous T, Fischbein MP.
Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):2195-2211. doi: 10.1161/ATVBAHA.120.314670. 
High-throughput Preparation of DNA, RNA, and Protein from Cryopreserved Human iPSCs for Multi-omics Analysis.
Zhang JX, Lau E, Paik DT, Zhuge Y, Wu JC.
Curr Protoc Stem Cell Biol. 2020 Sep;54(1):e114. doi: 10.1002/cpsc.114.
Opportunities and challenges of implementing computed tomography fractional flow reserve into clinical practice.
Nazir MS, Mittal TK, Weir-McCall J, Nieman K, Channon K, Nicol ED.
Heart. 2020 Sep;106(18):1387-1393. doi: 10.1136/heartjnl-2019-315607.
Cost-effectiveness of Canakinumab for Prevention of Recurrent Cardiovascular Events.
Yu J, Zhou Z, Mahaffey KW, Matthews DR, Neuen BL, Heerspink HJL, Jardine MJ, Li J, Perkovic V, Neal B, Arnott C.
Int J Cardiol. 2020 Sep 24:S0167-5273(20)33831-6. doi: 10.1016/j.ijcard.2020.09.050.
An assessment of the role of vinculin loss of function variants in inherited cardiomyopathy.
Hawley MH, Almontashiri N, Biesecker LG, Berger N, Chung WK, Garcia J, Grebe TA, Kelly MA, Lebo MS, Macaya D, Mei H, Platt J, Richard G, Ryan A, Thomson KL, Vatta M, Walsh R, Ware JS, Wheeler M, Zouk H, Mason-Suares H, Funke B.
Hum Mutat. 2020 Sep;41(9):1577-1587. doi: 10.1002/humu.24061. 
Healthy lifestyle and risk of incident heart failure with preserved and reduced ejection fraction among post-menopausal women: The Women's Health Initiative study.
Noel CA, LaMonte MJ, Roberts MB, Pearlman DH, Banack H, Allison M, Shadyab AH, Haring B, Laddu D, Martin LW, Nguyen PK, Manson JE, Eaton CB.
Prev Med. 2020 Sep;138:106155. doi: 10.1016/j.ypmed.2020.106155.
Evaluation of a Health Care Performance Improvement Initiative to Facilitate Optimal Clinical Outcomes in Patients Receiving Ventricular Assist Device Support.
Lockard KL, Dunn E, Kunz N, Pearsol A, Schaub RD Jr, Severyn DA, Lohmann D, McCall M, Morelli B, Teuteberg JJ, Kormos RL, Sciortino CM, Dew MA.
Prog Transplant. 2020 Sep 28:1526924820958129. doi: 10.1177/1526924820958129.
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program.
Klarin D, Verma SS, Judy R, Dikilitas O, Wolford BN, Paranjpe I, Levin MG, Pan C, Tcheandjieu C, Spin JM, Lynch J, Assimes TL, Nyrønning LÅ, Mattsson E, Edwards TL, Denny J, Larson E, Lee MTM, Carrell D, Zhang Y, Jarvik GP, Gharavi AG, Harley J, Mentch F, Pacheco JA, Hakonarson H, Skogholt AH, Thomas L, Gabrielsen ME, Hveem K, Nielsen JB, Zhou W, Fritsche L, Huang J, Natarajan P, Sun YV, DuVall SL, Rader DJ, Cho K, Chang KM, Wilson PWF, O'Donnell CJ, Kathiresan S, Scali ST, Berceli SA, Willer C, Jones GT, Bown MJ, Nadkarni G, Kullo IJ, Ritchie M, Damrauer SM, Tsao PS.
Circulation. 2020 Sep 28. doi: 10.1161/CIRCULATIONAHA.120.047544.
Incidence and outcomes of patients with atrial fibrillation and major bleeding complications: from the TREAT-AF study.
Perino AC, Kaiser DW, Lee RJ, Fan J, Askari M, Schmitt SK, Turakhia MP.J Interv Card Electrophysiol. 2020 Sep 28. doi: 10.1007/s10840-020-00873-0.
Mediators of the effects of canagliflozin on kidney protection in patients with type 2 diabetes.
Li J, Neal B, Perkovic V, de Zeeuw D, Neuen BL, Arnott C, Simpson R, Oh R, Mahaffey KW, Heerspink HJL.
Kidney Int. 2020 Sep;98(3):769-777. doi: 10.1016/j.kint.2020.04.051. 
Inpatient admissions and costs for adolescents and young adults with congenital heart defects in New York, 2009-2013.
Hsu WH, Sommerhalter KM, McGarry CE, Farr SL, Downing KF, Lui GK, Zaidi AN, Hsu DT, Van Zutphen AR.Birth Defects Res. 2020 Sep 29. doi: 10.1002/bdr2.1809. 
Single-cell protein expression of hiPSC-derived cardiomyocytes using Single-Cell Westerns.
Jabart E, Molho J, Sin K, Stansfield B, Kazmouz SG, Ventro D, Gardner K, Wu JC, Churko JM.
J Mol Cell Cardiol. 2020 Sep 30:S0022-2828(20)30292-3. doi: 10.1016/j.yjmcc.2020.09.012.
Early Change in Albuminuria with Canagliflozin Predicts Kidney and Cardiovascular Outcomes: A PostHoc Analysis from the CREDENCE Trial.
Oshima M, Neuen BL, Li J, Perkovic V, Charytan DM, de Zeeuw D, Edwards R, Greene T, Levin A, Mahaffey KW, De Nicola L, Pollock C, Rosenthal N, Wheeler DC, Jardine MJ, Heerspink HJL.J Am Soc Nephrol. 2020 Sep 30:ASN.2020050723. doi: 10.1681/ASN.2020050723. 
Cardiovascular CT in a world adrift.
Nieman K.
J Cardiovasc Comput Tomogr. 2020 Sep-Oct;14(5):381. doi: 10.1016/j.jcct.2020.08.002.
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