A 2016 systematic review of 74 articles assessed religion’s impact on mental health. It found an inverse association between religious practice and depression, anxiety, suicide, and substance use. It also found that religion improved the ability to cope with stress and hardship, depression, and anxiety. Finally, it found that youths who attended worship services and considered religion as important were less likely to use addictive substances.

A 2021 Turkish study examined the relationship between meaning in life and loneliness, as well as how religious coping habits mediated this relationship. Participants included 242 males and 360 females aged 18 and older from Turkey. Meaning in life was measured with the Presence of Meaning Scale, religious coping with the Religious Coping Scale, and loneliness with the revised UCLA Loneliness Scale. The study found that meaning in life had significant effects on loneliness and that religious coping strategies mediated this relationship.