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M&I Newsletter
October 2022

Honors, Awards & Recognition...

Congratulations to Jennifer Bomberger for her appointment to professor with tenure.

Congratulations to the following Pioli lab member
  • Chris Park received a Convergence Scholarship to attend the 2022 American College of Rheumatology (ACR) Meeting in Philadelphia from the Rheumatology Research Foundation. Chris' abstract was also selected for Lightning poster/talk presentation at the ACR Meeting.
🖌 Design Contest


We are looking for a new M&I Department Newsletter logo!
In addition, we will feature contestant art in future editions.
Drawings will be done for both BioRender and mixed media entries as applicable. 

Submit entries to Microbiology.and.Immunology@dartmouth.edu

Prizes will include gift certificates up to $45.00
Recent Publications
 
Azizul Haque, Anudeep B. Pant

Resident memory CD8+ T cells in regional lymph nodes mediate immunity to metastatic melanoma
Aleksey K. Molodtsov, Nikhil Khatwani, Jennifer L. Vella, Yina H. Huang, Chao Cheng, Mary Jo Turk

The future of fungi: threats and opportunities.
Case NT, Berman J, Blehert DS, Cramer RA, Cuomo C, Currie CR, Ene IV, Fisher MC, Fritz-Laylin LK, Gerstein AC, Glass NL, Gow NAR, Gurr SJ, Hittinger CT, Hohl TM, Iliev ID, James TY, Jin H, Klein BS, Kronstad JW, Lorch JM, McGovern V, Mitchell AP, Segre JA, Shapiro RS, Sheppard DC, Sil A, Stajich JE, Stukenbrock EE, Taylor JW, Thompson D, Wright GD, Heitman J, Cowen LE
G3 (Bethesda). 2022 Sep 30; pii: jkac224. doi: 10.1093/g3journal/jkac224. Epub 2022 Sep 30.
PMID: 36179219

Optimal transcriptional regulation of dynamic bacterial responses to sudden drug exposures.
Schultz D, Stevanovic M, Tsimring LS
Biophys J. 2022 Sep 26; pii: S0006-3495(22)00778-0. doi: 10.1016/j.bpj.2022.09.028. Epub 2022 Sep 26.
PMID: 36168291

Maternally transferred mAbs protect neonatal mice from HSV-induced mortality and morbidity.
Backes IM, Byrd BK, Slein MD, Patel CD, Taylor SA, Garland CR, MacDonald SW, Balazs AB, Davis SC, Ackerman ME, Leib DA
J Exp Med. 2022 Dec 5;219(12) pii: e20220110. doi: 10.1084/jem.20220110. Epub 2022 Sep 26.
PMID: 36156707

Multifunctional Plant Virus Nanoparticles for Targeting Breast Cancer Tumors.
Shahgolzari M, Dianat-Moghadam H, Yavari A, Fiering SN, Hefferon K
Vaccines (Basel). 2022 Aug 30;10(9) pii: 1431. doi: 10.3390/vaccines10091431. Epub 2022 Aug 30.
PMID: 36146510

Proactive Immunotherapeutic Approaches against Inflammatory Breast Cancer May Improve Patient Outcomes.
Alonso-Miguel D, Fiering S, Arias-Pulido H
Cells. 2022 Sep 13;11(18) pii: 2850. doi: 10.3390/cells11182850. Epub 2022 Sep 13.
PMID: 36139425

Mitochondrial dysfunction triggers actin polymerization necessary for rapid glycolytic activation.
Chakrabarti R, Fung TS, Kang T, Elonkirjo PW, Suomalainen A, Usherwood EJ, Higgs HN
J Cell Biol. 2022 Nov 7;221(11) pii: e202201160. doi: 10.1083/jcb.202201160. Epub 2022 Sep 14.
PMID: 36102863

Post-partum female who woke up with hemiparesis.
Wira CR 3rd, Marcolini E, Bulsara KR
J Am Coll Emerg Physicians Open. 2022 Oct;3(5):e12807. doi: 10.1002/emp2.12807. Epub 2022 Sep 5.
PMID: 36090003

Intraspecies Signaling between Common Variants of Pseudomonas aeruginosa Increases Production of Quorum-Sensing-Controlled Virulence Factors
Dallas L. Mould, Nico J. Botelho, Deborah A. Hogan
DOI: 10.1128/mBio.01865-20

Analysis of CRISPR/Cas9 Guide RNA Efficiency and Specificity Against Genetically Diverse HIV-1 Isolates
Katherine J. Sessions, Yun Yue Chen, Christine A. Hodge, Taylor R. Hudson, Susan K. Eszterhas, Matthew S. Hayden, and Alexandra Howell
DOI: 10.1089/aid.2020.0055

Conditional antagonism in co-cultures of Pseudomonas aeruginosa and Candida albicans: An Intersection of etanol and phosphate signaling distilled from dual-seq transcriptomics
Georgia Doing, Katja Koeppen, Patricia Occipinti, Colleen E. Harty, Deborah A. Hogan
DOI: 10.1371/journal.pgen.1008783

Belly Fat Weakens Immune Fitness
Jose R Conejo-Garcia 1 2 3, Tyler J Curiel 4 5 6
Affiliations expand
PMID: 35929132

DOI: 10.1158/2159-8290.CD-22-0611

Selective delipidation of Mycobacterium bovis BCG retains antitumor efficacy against non-muscle invasive bladder cancer
Niannian Ji # 1 2, Meijun Long # 2 3, Andreu Garcia-Vilanova 4, Russell Ault 4, Juan I Moliva 5, Kizil A Yusoof 4, Neelam Mukherjee 1 2, Tyler J Curiel 1 6, Hong Dixon 7, Jordi B Torrelles 8, Robert S Svatek 9 10
Affiliations expand

PMID: 35748904 DOI: 10.1007/s00262-022-03236-y

Surface-Induced cAMP Signaling Requires Multiple Features of the Pseudomonas aeruginosa Type IV Pili
Sherry L Kuchma 1, George A O'Toole 1
Affiliations expand
PMID: 36073942 DOI: 10.1128/jb.00186-22


Send submissions to Brooke Therriault, Research Admin., using this link:  Science Artwork

Please send submissions in a high resolution format, and include a figure legend and credits.  The best submissions will join the M&I “walls of fame”!
Congratulations on new funding...
 
  • Tyler Curiel, Bladder cancer PD-L1 control of the DNA damage response: Basic mechanisms applied to novel treatments, R01 CA268641, 8/15/22
  • Tyler Curiel, Fine tuning IL2R-targeted cancer immunotherapies to improve effector and memory induction, Bladder Cancer Advocacy Network, 8/05/22
  • Yina Huang, CAR T platform to treat solid tumors, Celdara/ NIH/National Cancer Institute, 8/1/22
  • Ed Usherwood, Exploiting a novel regulator of immunometabolism to enhance immunotherapy, NIH/National Cancer Institute, 07/01/22
  • Deb Hogan, Complex inhibition of proteases produced by CF pathogens, CFF, 11/01/22
  • Sandeep Vellanki, postdoctoral fellow in the Cramer Lab, Complex inhibition of proteases produced by CF pathogens, CFF fellowship, 11/01/22
  • Robert Cramer, Home sputum collection for Aspergillus fumigatus detection in cystic fibrosis, CFF, 8/31/22
  • Chuck Wira, Supplement - Impact of Aging on Mucosal Immune Protection in the Female Reproductive, NIH/ National Institute on Aging, 9/5/22
  • Steve Fiering, Toward translation of a plant virus-based in situ vaccination nanotechnology, UCSD/NIH/National Cancer Institute, 8/22/22
  • Steve Fiering, Dual-pronged nano-drug delivery using plant virus-like particles, UCSD/NIH/National Cancer Institute,  9/15/22
  • James Bliska, Regulation of host innate and adaptive immunity by bacterial type III effectors, NIAID, 09/20/22
  • Bruce Stanton, Retrieval, Reprocessing, Normalization and Sharing of Gene Expression and Lung Microbiome Data Sets to Facilitate AI/ML Analysis Studies of Bacterial Lung Infections, NHLBI, 07/29/22
Neighborhood News...
Usherwood Lab happy in their new surroundings at 7 Rubin.  
     
Lori Dickerson, Sr. Research Admin., had a wonderful vacation in Portland with grandsons, Hugo & Sawyer!
Students and staff enjoying our September fall pop-up event.
Upcoming M&I Annual Pumpkin Fest!

Location:  Guarini Commons and Lawn


 
                        

                     
ADMINISTRATIVE UPDATES

As always, please send backup and inquiries to Microbiology.and.Immunology@dartmouth.edu  


 

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