PolySciTech Products In Literature
PLGA-NH2 from PolySciTech used in testing nanoparticles for platinum-based anticancer therapy
Cisplatin is the first FDA-approved metal-based drug for the treatment of solid tumors as it uses platinum as an active agent. In the bloodstream, however, it reacts with glutathione which diminishes its effectiveness. Recently, researchers at the City University of New York used PLGA-NH2 (AI010) from PolySciTech to make Cy5.5 labeled nanoparticles for tracking purposes as part of their research in making nanoparticles for delivery of cisplatin. This research holds promise for improving treatments against cancer. Read more: Marek T. Wlodarczyk “Enhanced Platinum (II) Drug Delivery for Anti-cancer Therapy” PhD Dissertation City University of New York, 2021
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PLGA-PEG-COOH from PolySciTech used in development of carborane-loaded nanoparticles for prostate cancer treatment
PSMA is a marker that is overexpressed on cancer cells and can provide an attractive target for ligand-based therapies. Recently, researchers at the University of California San Francisco used PLGA-PEG-COOH (AI078) from PolySciTech to create PSMA-targeting nanoparticles loaded with carborane for boron neutron capture therapy against prostate cancer. This research holds promise to improve therapeutic options for cancer. Read more: Meher, Niranjan, Kyounghee Seo, Sinan Wang, Anil P. Bidkar, Miko Fogarty, Suchi Dhrona, Xiao Huang et al. "Synthesis and Preliminary Biological Assessment of Carborane-Loaded Theranostic Nanoparticles to Target Prostate-Specific Membrane Antigen." ACS Applied Materials & Interfaces (2021).
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Print what you want with the latest bioresorbable polymer technology. AKiNAfil™ bioresorbable PLGA polymers reformatted in standardized 1.7 mm filament available in a variety of lengths. The PLGA polymers are coformulated with FDA-GRAS and biocompatible acetyltriethylcitrate (ATEC) plasticizer for improved processability and provide for biorelevant degradation properties to be used in a wide array of biomedical applications. |
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Browse through our searchable list of research
that reference the use of PolySciTech products.
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PolySciTech Division of Akina, Inc. (www.polyscitech.com) provides a wide array of biodegradable polymers and other research supplies. Visit our website to find out more.
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