In a study conducted by neuroscientists at the Swiss Federal Institute of Technology, it was discovered that there may be some potential in analyzing the specific neurons in control of bodily repair after a spinal cord injury, allowing these patients to walk after having experienced paralysis. In 2018, the neuroscientists explored the activity of the nerves of nine patients a few of which were completely paralyzed in the lower half of their body. While investigating, the scientists found that certain groups of neurons or networks were operating during the recovery period, while others remained dormant. However, this idea was still quite novel and required much more research, so they decided to take their study one step further and examine their findings within mice, replicating the injuries the humans faced.
Through the use of machine learning in the gene expression, the scientists learned that specific nerve cells connecting sensory and motor neurons inside the mice were being expressed and activated during the recovery process of learning to walk once again. When the scientists regulated the neurons through optogenetics and prohibited these nerve cells from being expressed, the mice were no longer able to walk. Although the use of optogenetics is currently not feasible within human bodies, the study is quite promising and can hopefully be conducted soon and applied in the medical field to accelerate the recovery process after a severe injury.
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