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Institute for Addiction Science

Issue 37

IAS UPDATES
Welcome to the May Issue of the IAS Newsletter!

As the school year comes to an end, we’d like to take a moment to honor the exceptional addiction science students and early career researchers affiliated with the institute. CONGRATULATIONS STUDENTS AND GRADUATES! The team at IAS are committed to uplifting students and supporting their growth in the field and we are so proud of the work you have accomplished. In May, we plan to continue championing students through our education programming, build on our community outreach, and cultivate more impactful research that changes the course of addiction science.

EDUCATION UPDATES

On April 25th, IAS held the annual Early Career Addiction Showcase (ECASS). The event was a huge success with 8 presentations and 13 posters on various topics by students from multiple schools across USC. This event truly reflected the transdisciplinary nature of IAS and captured the spirit of IAS’s mission to inspire innovation in the field. Congratulations to the brilliant early career addiction researchers who contributed to this event! Click here to see descriptions of the presentations and posters. A big congratulations to the ECASS winners:
  • Meritorious Undergraduate Level Presentation : Ariana Coba Clementel
  • Undergraduate Level Presentation : Giselle Soto Rivas
  • Meritorious Masters/Post-Bac Level Presentation : Keegan Buch
  • Masters/Post-Bac Level Presentation : Griffin Riggs
  • Meritorious PhD Student Level Presentation : Siddhi Ganesh
  • PhD Student Level Presentation : Jesse Goldshear
  • Meritorious Post-Doctoral Level Presentation: Brigid Conn
  • Post-Doctoral Level Presentation: Emily Johnson
On April 27th, the current and prospective Addiction Science minor students were invited to mingle with IAS faculty and celebrate the end of the school year at the Minor in Addiction Science Social. We congratulated the Spring 2023 minor in Addiction Science graduates who will no doubt go on to make a lasting impact in solving the addiction crisis. Lianna Treitler is graduating with a B.A. in Psychology and plans to attend law school and work in the field of policy and advocacy. Giselle Soto Rivas is graduating with a B.A. in Health and Human Sciences and hopes to go to medical school after taking a gap year. And Jenae Cipolla is graduating with a B.A. in Psychology and plans to apply to clinical psychology doctoral programs in the near future. We are so proud of you, graduates! We can’t wait to see what you do next.



COMMUNITY ENGAGEMENT UPDATES

April’s Distinguished Speaker Series featured nationally recognized scholar, Joseph LaBrie, PhD. Dr. LaBrie spoke on the topic of “Rethinking Brief Substance Use Interventions: Including Novel Social Media Methods and Gamification to Increase Reach and Effectiveness.” He discussed the effectiveness of gamification in personalized normative feedback (PNF) interventions and posited that gamification can increase the efficacy of these interventions. Watch the talk here!

Our next Distinguished Speaker Series guest will be Julia Dilley, PhD, MES. Dr. Dilley is a Senior Research Scientist and Epidemiologist with Multnomah County Health Department and State of Oregon Public Health Division. Her current research focuses on the public health effects of law and policy around cannabis, alcohol, tobacco, and illicit drugs. Since 2016, she has co-chaired the nationwide Council of State & Territorial Epidemiologists (CSTE) Cannabis Subcommittee, leading efforts to identify the best measures and methods for cannabis-related public health monitoring. Her talk is titled: “Youth Cannabis Use and Risk Factors in the Pacific Northwest: Do Local Cannabis Retail Stores Affect Youth?” Learn more on May 10, 2023 at 12pm PDT. Register here.
 
On June 1, 2023, IAS and the Center for Behavior and Addiction Management (CBAM) will be screening a film titled “Swallow THIS: A Documentary About Methadone and COVID-19.” This documentary reveals how methadone clinic policy changes during the COVID-19 pandemic lead to liberating new ways for patients to receive methadone. This screening will feature a Q&A session with the film’s directors and an expert panel discussion. Be sure to register here!

FACULTY HIGHLIGHTS

Our mission at IAS is to support the success of addiction scientists in all levels of their career. From undergraduate student to faculty member and beyond. Denise Tran, PhD's story is a prime example of IAS’s aim in empowering addiction researchers. Dr. Tran started her career as a mentee to IAS member Dr. Eric Pedersen. She applied for an pilot award to collect pilot data which then turned into her project for her K01. Now she is an associate faculty member at USC Keck School of Medicine!  Kudos to you, Dr. Tran!

Congratulations as well to IAS member Cameron Kaplan, PhD on his promotion to Associate Professor of Medicine with Tenure! Not only that, Dr. Kaplan was also named the Interim Director of the Gehr Family Center for Health System Science and Innovation, a huge honor!  Dr. Kaplan is a health economist at the USC Schaeffer Center with a focus on the impact of health policy and insurance benefit design on healthcare utilization, health outcomes, and disparities. IAS is proud to have Dr. Kaplan as a member and we are thrilled to see his hard work and dedication be rewarded.

MISCELLANEOUS

The FDA has just approved Narcan nasal spray for over-the-counter (OTC), nonprescription, use – the first naloxone product approved for use without a prescription. This change will make the life-saving drug more accessible and will likely lead to an increase in overdose reversals in the US. According to the FDA, “Naloxone is a medication that rapidly reverses the effects of opioid overdose and is the standard treatment for opioid overdose.” With this approval, Narcan can be purchased in drug stores, convenient stores, gas stations, and grocery stores across the country. Read the full announcement here.

As always, we are very appreciative of your continued support of the Institute for Addiction Science and look forward to continuing to share our ongoing and upcoming projects and activities with you.

Warmest Regards,
Adam Leventhal, John Clapp, Daryl Davies, Ricky Bluthenthal, Terry Church, Vickie Williams, Loba Ojo, and Jillian Boelke
UPCOMING EVENTS AND MEETINGS
IAS 2022 Distinguished Speaker Series - May 2023 Speaker Event:



This talk will be in-person at the Soto Street Building Room 116

1845 N. Soto Street Los Angeles, CA 90032
Lunch and parking provided.
(Please see receptionist upon arrival and she will provide you with a parking permit to place on your dashboard.)

(virtual attendance via zoom will also be available)

Click here to register
 

Special film screening of “Swallow THIS:  A Documentary About Methadone and COVID-19”
 

Special film screening of “Swallow THIS:  A Documentary About Methadone and COVID-19”
 
Thursday, June 1, 2023
5:00pm – 7:00pm PDT (Doors open at 4:30pm)
 
USC Bovard Auditorium
3551 Trousdale Pkwy.
Los Angeles, CA
(Parking provided in the McCarthy Structure)
 
Please join IAS, UCLA’s Center for Behavioral and Addiction Medicine (CBAM), and directors – Marilena Marchetti and Helen Redmond –  for this special event!
 
This 30-minute documentary reveals what happened in methadone clinics du ring the pandemic.  Federal agencies lifted restrictions on take-home doses so every person was eligible for 14 or 28 days of medication.  Many patients experienced a liberation they never knew was possible.
 
There will also be a special Q&A discussion with the directors and expert panelists immediately following the film screening. 
 
Please share this with friends, colleagues, faculty, community partners, and students!  All are welcome to attend.
 
Registration is required.  Please click here to RSVP.
 

On June 9, 2023 there will be an Addiction Science Research Training Retreat at the California Endowment from 8:00am – 5:00pm PST. Hosted by Charles Drew with collaborators from UCLA and UCI, this 2nd annual event will feature five training programs in Southern California, two of which involve USC IAS.
  • Univ. Southern California Institute for Addiction Science
  • CA State Univ. San Bernardino Smoke and Tobacco Outreach and Prevention Scholars (STOPS) program
  • UCLA T32 Program in the Translational Neuroscience of Drug Abuse
  • UC Irvine T32 Training Program in Substance Use and Use disorders
  • Drew Medical University
Keynote Speakers:
  • Adam Leventhal, PhD – Director of USC Institute for Addiction Science
  • Wilson Compton, MD MPE – Deputy Director of the National Institute on Drug Abuse
We encourage you to invite any research trainees you work with to attend this retreat as this will be a wonderful opportunity for trainees to learn more about the addiction science research training programs that are going on in Southern California as well as network with other leaders in the field. There is no cost to attend and the invite is open to everyone, not just trainees. Email Vickie Williams at victoria.williams.0@usc.edu to RSVP.
 
FUNDING OPPORTUNITIES
FUNDING FOR HIGH IMPACT TRANDISCIPLINARY PROJECTS

As a reminder, IAS is requesting project ideas from any IAS participating faculty members to award seed funding that will lead to high impact transdisciplinary projects.  Projects that will advance any of IAS’s three missions—research, education, and community engagement and service—are encouraged.  These project pitches will require a brief one-page description and budget and should propose work that can be completed within 1-year, but serve as the basis for a longer-term initiative, as described here.      
 
 CALL FOR DEMONSTRATION & PILOT PROJECT PROPOSALS
using the new IAS Biobehavioral Research Facility
IAS is requesting proposals for demonstration projects using IAS’s newly renovated state-of-the-art 2,600 square foot clinical research space expressly designed for addiction science at the USC Health Science Campus.  This facility includes a room designed to be used a simulated bar, cannabis dispensary, or tobacco retail space; separate research participation suites with one-way mirrors equipped with ventilation to clear smoke for inhalational drug administration studies; reception and waiting area; offices and conference room; access biospecimen storage; and private patient counseling and exam space. 
 
A total of $100,000 will be awarded, divided amongst a cluster of demonstration or pilot projects using the space.  Projects proposing to use any component of the facility are welcomed.  Demonstration projects leveraging the simulated bar/tobacco retailer/cannabis dispensary space are especially encouraged that will provide an infrastructure to support new collaborative multi-investigator/multi-study collaborative research programs. The seed funding should be used as preliminary data to compete for subsequent larger external grants (e.g., NIH P50, P01, U54, R01, U01, R21, R03).
 
It is highly recommended that prospective applicants discuss their proposals with one of the translational and treatment development research program leaders - John Monterosso (johnrmon@usc.edu), Daryl Davies (ddavies@usc.edu), or Adam Leventhal (adam.leventhal@usc.edu) – while developing the proposal and budget.  This will help ensure synergy across submissions and optimize fit with funding priorities.
 
Guidelines and Submission
 
Components (all single spaced with 0.5” margins, 11pt font):
 
  • Cover page including: (a) the names, professional titles, affiliations (school/department), and email address of the PI and each investigator, (b) the title of the proposal
  • Biosketches or CVs of the PI and each investigator (<5 pages each).
  • A brief narrative describing (1-2 pages total):
    • Specific aims and scientific premise
    • An abbreviated overview of methods, including explaining how the facility will be used.
    • Rationale and plan of how the project will be used to compete for subsequent external funding
    • Explanation of how frequently you anticipate using the space
    • Total anticipated budget needed
 
Reporting.  All projects selected for funding will be required to submit a 6 month and annual progress report and present on the findings from the project upon completion at a future IAS Institute-Wide Meeting to Research Program Meeting.
 
Application Procedures.  Please send your application with all above components in single PDF document to Victoria.williams.0@usc.edu
IAS MEMBER RESEARCH CORNER

Below are selected publications from the previous month (April 2023) from faculty members and scholars of the Institute for Addiction Science. 

Barocas, J. A., Nall, S. K., Axelrath, S., Pladsen, C., Boyer, A., Kral, A. H., . . . Xia, M. (2023). Population-level health effects of involuntary displacement of people experiencing unsheltered homelessness who inject drugs in US cities. JAMA. doi:10.1001/jama.2023.4800

Davis, J. P., Pedersen, E. R., Borsari, B., Bowen, S., Owen, J., Sedano, A., . . . Bunyi, J. (2023). Development of a mobile mindfulness smartphone app for post-traumatic stress disorder and alcohol use problems for veterans: Beta test results and study protocol for a pilot randomized controlled trial. Contemporary Clinical Trials, 129, 107181. doi:10.1016/j.cct.2023.107181

Harlow, A. F., McConnell, R., Leventhal, A. M., Goodwin, R. D., & Barrington-Trimis, J. L. (2023). Racial, ethnic, and education differences in age of smoking initiation among young adults in the United States, 2002 to 2019. JAMA Network Open, 6(3). doi:10.1001/jamanetworkopen.2023.5742

Johnson, E., Axeen, S., Vosooghi, A., Lam, C. N., Bluthenthal, R., & Schneberk, T. (2023). Interrupted time series analysis: Patient characteristics and rates of opioid-use-disorder-related emergency department visits in the Los Angeles County Public Hospital system during COVID-19. Healthcare, 11(7), 979. doi:10.3390/healthcare11070979

Lee, B. P., & Terrault, N. A. (2023). Liver transplantation for alcohol-associated liver disease: A call for national standards of best practices to monitor and bridge disparities in access and outcomes. American Journal of Transplantation. doi:10.1016/j.ajt.2023.03.026

Oh, H., Du, J., Karcher, N. R., Van der Ven, E., DeVylder, J. E., Smith, L., & Koyanagi, A. (2023). The separate and joint effects of recent interpersonal abuse and cannabis use on psychotic experiences: Findings from students in Higher Education in the United States. Social Psychiatry and Psychiatric Epidemiology. doi:10.1007/s00127-023-02483-3

Rodgers, R. F., Smith, K., & Murray, S. B. (2023). Cognitive rigidity and restrictive eating disorders: Delineating the impact of low weight, low fat, weight suppression, acute negative energy balance, and chronic restriction. International Journal of Eating Disorders. doi:10.1002/eat.23937

Tran, D. D., Davis, J. P., Tucker, J. S., Bricker, J., Lee, D. S., Fitzke, R. E., & Pedersen, E. R. (2023). Cigarette smoking and depression among US veterans: Longitudinal associations with posttraumatic stress disorder. Nicotine and Tobacco Research. doi:10.1093/ntr/ntad064

Tran, D. D., Prince, M. A., Fitzke, R. E., Ring, C., Barrington-Trimis, J., & Pedersen, E. R. (2023). Preliminary development of the protective behavioral strategies for vaping scale. Addictive Behaviors, 144, 107728. doi:10.1016/j.addbeh.2023.107728

ADDICTION SCIENCE IN THE NEWS
This section highlights a few news articles from the month highlighting research or programming from an IAS member or IAS research program, as well as articles related to addiction science. 

Moderate Drinking Has No Health Benefits, Analysis of Decades of Research Finds 
The New York Times, April 4th, 2023 

As Mental Health Crisis Grows, More Doors Open to Care
The New York Times, April 11th, 2023

White House Designates Animal Sedative as an "Emerging Drug Threat"
The New York Times, April 12th. 2023

In Jails and Prisons, the White House Sees a Chance to Curtail Opioid Overdoses 
The New York Times, April 21st, 2023

This Is What Neuroscientists and Philosophers Understand About Addiction 
The New York Times, April 24th, 2023

Emergence of deadly fentanyl-xylazine combo 'tranq' worsens the addiction epidemic 
USC News, April 27th, 2023

Sounds from nature: A soothing remedy for gambling addiction 
Newswise, April 27th, 2023
JOB OPPORTUNITIES

Students needed to assist with research study:

The USC PEARL Lab is currently recruiting US veterans (aged 18-40) for a research study where we are testing whether a brief online intervention (a 20-minute interactive program viewable on phones) can help veterans reduce their drinking and seek more formal care for their alcohol use or behavioral health problems (like PTSD, depression). We are recruiting off social media and have a lot of potential participants ready to be enrolled. But due to the nature of online advertising, we need to call veterans and verify a few key pieces of information with them to ensure they are who they say they are (and not people just pretending to be veterans to get our incentives). We’re looking for students to help us make these calls, which take about 5 minutes. Nearly everyone we’ve called has “passed” this verification check so it’s just an extra precaution. Calls could be made anytime of the day, but we’ve found closer to the evening time works best to get ahold of participants. There is a script for the calls. Students will be interacting with participants so they will have needed to complete the CITI training. We’re looking for students who can start as soon as late April, with calls lasting likely through August.  Please contact Eric Pedersen at eric.pedersen@med.usc.edu.
 

The Tobacco Related Disease Research Program is looking to hire an Associate Program Officer.  The successful applicant will join a team of 8 other program officers, a director, and support staff in sunny Oakland, California.

The Associate Program Officer will play a key role in the development and management of research grant making activities and special projects within the Tobacco-Related Disease Research Program. The incumbent will have key responsibilities in managing external communications and program evaluation. The applicant should possess considerable expertise collecting and analyzing program review and outcomes data associated with nicotine or tobacco use. Advanced knowledge of or experience with addressing social determinants of health and advancing health equity is also required.
 

Marshall University has two open positions in their Psychology department. Marshall University is located in Huntington, WV, which is heavily impacted by the opioid epidemic. As such, there are excellent opportunities here for addictions researchers and clinicians, including some ongoing interdisciplinary efforts in both the university and the community. There are two tenure-track Assistant Professor positions available, with a third to be posted soon. The first position requires a degree in clinical or counseling psychology and includes teaching in the PsyD program as well as opportunities to work with undergraduates. The second is open regarding area, with a preference for individuals interested in teaching courses at all levels related to methodology and statistics. The third position should be posted soon and will also require a degree in clinical or counseling psychology and include teaching in our PsyD program. Please feel free to share this information with any students, post-docs, etc. who may be interested!
 

Research Team - Department of Population and Public Health Sciences
 
The Department of Population and Public Health Sciences is in search of: A dependable, flexible, and detail-oriented person is needed to join a research team at the University of Southern California to participate in new pilot studies related to substance use, including studies related to cannabis use during pregnancy. These studies are investigating harm reduction approaches to substance use, including how expanding cannabis legalization may worsen existing maternal health disparities.
 
Employment Involves:
(1) Data collection. Conducting one-on-one interviews and focus groups with study participants (e.g., people who inject drugs, women who use cannabis during pregnancy, young women who vape, health providers and midwives);
(2) Data analysis. Conducting data analysis (e.g., thematic analysis, grounded theory using ATLAS.ti);
(3) Project management. Supporting all study-related project and data management (e.g., Institutional Review Board submissions and related protocols, managing and storing data according to HIPAA, managing
transcription of data).
 
 
Excellent English writing and speaking skills are required, and bilingual in English and Spanish writing and speaking skills are ideal. The ideal candidate will have strong organizational capabilities, superb problem-solving skills, and a demonstrated ability to work independently while managing multiple tasks. Opportunities for mentorship and support in writing manuscript writing and peer-reviewed publications are available. Flexible hours on some evenings and weekends may be needed (e.g., conducting research interviews to accommodate study participants’ schedules). The majority of the work will be conducted remote from 9am-5pm Monday through Friday). Prior experience in a research environment is preferred.Bachelor’s or Master’s degree in the social sciences or in a health related field is preferred. 

For more information or to apply, please email Rachel Carmen Ceasar, PhD, Assistant Professor of Population and Public Health Sciences at rceasar@usc.edu. 

 
REMINDERS
Training Opportunities
Please let us know of any opportunities/needs you may have for a trainee on any of the research projects you are currently working on or are planning for!  We are always looking to match interested early career, graduate, or undergraduate level trainees with faculty who can provide a training/mentorship openings.  Please fill out this form to be added to our IAS database. 


Minor in Addiction Science - Registration is Open!

This minor is designed for students with an interest in addiction who plan to enter medical, pharmaceutical, social work, or other graduate programs, or who are interested in pursuing a career in which a background in addiction may prove beneficial. 

Courses and research are delivered from broad areas of expertise within - Preventive Medicine, Pharmacy, Social Work, and Psychology. Students will gain a real-world understanding and recognize that addictive behaviors exist within a complex environment involving commercial - economic, political, and sociocultural forces.



Masters in Addiction Science (MAS) is now accepting applicants!  Please share this information link to prospective students: www.tinyurl.com/USCMAS
GRANT ANNOUNCEMENTS
Title Release Date Code Issuing Org FOA/Notice #
Pathway to Independence Award in Tobacco Regulatory Research (K99/R00  - Independent Clinical Trial  Required ) 11/10/2022 K99/R00 ODP RFA-OD-22-026
Pathway to Independence Award in Tobacco Regulatory Research (K99/R00  - Independent Clinical Trial Not Allowed) 11/10/2022 K99/R00 ODP RFA-OD-22-025
Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 -  Independent Clinical Trial Required) 11/10/2022 K01 ODP RFA-OD-22-024
Mentored Research Scientist Career Development Award in Tobacco Regulatory Research (K01 - Independent Clinical Trial Not Allowed) 11/10/2022 K01 ODP RFA-OD-22-023
Notice of Special Interest (NOSI): Chemoproteomic Approaches for Discovery of Targets and Therapeutics to Treat Substance Use Disorders 11/7/2022 R03,F32,R21,
F31,R01,
K99/R00,
F30,K01
NIDA NOT-DA-24-005
Notice of Special Interest (NOSI) Targeting Epigenetic Regulators for Treating Addiction and Substance Use Disorders 11/3/2022 R03,R01,
K99/R00,R21,
F31,F30,F32,K01
NIDA NOT-DA-24-004
Targeting Inflammasomes in Substance Abuse and HIV (R21 Clinical Trial Not Allowed) 11/3/2022 R21 NIDA RFA-DA-24-004
Targeting Inflammasomes in Substance Abuse and HIV (R01 Clinical Trial Not Allowed) 11/3/2022 R01 NIDA RFA-DA-24-003
Notice of Special Interest (NOSI): Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R01, R21, R03) 11/2/2022 R01,R03,R21 NIDA NOT-DA-23-012
Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders (R21/R33 Clinical Trial Not Allowed) 11/1/2022 R21/R33 NIDA PAR-23-041
Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NIDA Populations of Interest 10/20/2022 R15,R21,R01,R03 NIDA NOT-DA-22-084
Advancing Adolescent Tobacco Cessation Intervention Research (R01 Clinical Trial Required) 10/3/2022 R01 NCI RFA-CA-22-043
NIDA REI: Reaching Equity at the Intersection of HIV and Substance Use: Novel Approaches to Address HIV Related Health Disparities in Underserved Racial and/or Ethnic Populations (R01 Clinical Trial Optional) 10/3/2022 R01 NIDA RFA-DA-23-061
Notice of Special Interest (NOSI): HEAL Initiative: Grand Opportunity in Medications Development for Substance-Use Disorders 9/29/2022 U01 NIDA NOT-DA-23-009
Notice of Special Interest (NOSI): Research on the Impact of Policy Changes and Emerging and Evolving Public Health Crises on NICHD Populations of Interest 9/14/2022 R15,R03,R01,R21 NICHD NOT-HD-22-038
Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional) 9/1/2022 U01 NIDA PAR-22-202
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